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Boc-5-aminopentanoic acid

Product Name
Boc-5-aminopentanoic acid
CAS No.
27219-07-4
Chemical Name
Boc-5-aminopentanoic acid
Synonyms
BOC-5-AVA-OH;BOC-5-AMINOVALERIC ACID;5-(TERT-BUTOXYCARBONYLAMINO)VALERIC ACID;BOC-APE(5)-OH;Boc-5-Ava-OH 97%;BOC-NH-(CH2)4-COOH;RARECHEM EM WB 0073;Boc-d-aMinovaleric acid;5-(BOC-AMINO)VALERIC ACID;N-BOC-5-AMINOVALERIC ACID
CBNumber
CB8379946
Molecular Formula
C10H19NO4
Formula Weight
217.26
MOL File
27219-07-4.mol
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Boc-5-aminopentanoic acid Property

Melting point:
48-52 °C(lit.)
Boiling point:
160-168 °C0.8 mm Hg(lit.)
Density 
1.1518 (rough estimate)
refractive index 
1.4500 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Powder
pka
4.72±0.10(Predicted)
color 
Off-white
BRN 
2048862
CAS DataBase Reference
27219-07-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
10-21
HazardClass 
IRRITANT
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
475351
Product name
Boc-5-Ava-OH
Purity
97%
Packaging
5g
Price
$166
Updated
2023/06/20
Sigma-Aldrich
Product number
475351
Product name
Boc-5-Ava-OH
Purity
97%
Packaging
25g
Price
$658
Updated
2023/06/20
TCI Chemical
Product number
B2895
Product name
N-(tert-Butoxycarbonyl)-5-aminovaleric Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$89
Updated
2024/03/01
TCI Chemical
Product number
B2895
Product name
N-(tert-Butoxycarbonyl)-5-aminovaleric Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$301
Updated
2024/03/01
Alfa Aesar
Product number
H66168
Product name
5-(Boc-amino)valeric acid, 95%
Packaging
1g
Price
$26.7
Updated
2023/06/20
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Boc-5-aminopentanoic acid Chemical Properties,Usage,Production

Description

Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

solid

Uses

Boc-5-aminovaleric acid can be used to synthesize inhibitors of bacterial quorum seining and biofilm formation. It can also be used to synthesize diblock and triblock copolymers.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 2424, 1983 DOI: 10.1021/jo00162a028

Boc-5-aminopentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-5-aminopentanoic acid Suppliers

Americas 1 China 138 Europe 1 France 1 Germany 5 India 3 Japan 3 Switzerland 1 United Kingdom 2 United States 17 Global 172
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from Boc-5-aminopentanoic acid manufacturers

Career Henan Chemical Co
Product
Boc-5-aminopentanoic acid 27219-07-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-07

27219-07-4, Boc-5-aminopentanoic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Folic acid Glycine ALTRENOGEST 5-AMINOVALERIC ACID MAGNESIUM DIPROPYLACETATE HYDRATE Estradiol valerate 2-Propylpentanoic acid Pivalic acid N-Carbobenzyloxyglycine 1-(Boc-amino)cyclopropanecarboxylic acid BOC-HYP(BZL)-OH BOC-L-2-AMINOADIPIC ACID Boc-Hyp-OH (3S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid BOC-L-Proline N-Boc-trans-4-Hydroxy-L-proline methyl ester Fmoc-Orn(Boc)-OH

  • N-T-BUTOXYCARBONYL-5-AMINOPENTANOIC ACID
  • N-DELTA-T-BUTOXYCARBONYL-DELTA-AMINOVALERIC ACID
  • N-BOC-5-AMINOPENTANOIC ACID
  • N-BOC-5-AMINOVALERIC ACID
  • PENTANOIC ACID, 5-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-
  • RARECHEM EM WB 0073
  • 5-(TERT-BUTOXYCARBONYLAMINO)VALERIC ACID
  • 5-(TERT-BUTOXYCARBONYLAMINO)PENTANOIC ACID
  • 5-(BOC-AMINO)PENTANOIC ACID
  • 5-(BOC-AMINO)VALERIC ACID
  • 5-[(tert-Butyloxycarbonyl)amino]pentanoic acid
  • 5-[[(1,1-Dimethylethyl)oxy]carbonyl]aminopentanoic acid
  • BOC-NH-(CH2)4-COOH
  • BOC-APE(5)-OH
  • BOC-5-AMINOVALERIC ACID
  • BOC-5-AVA-OH
  • BOC-5-AMINOPENTANOIC ACID
  • BOC-DELTA-AMINOVALERIC ACID
  • Boc-5-AMinovaleric acid Boc-5-AMinovaleric acid
  • 5-(Boc-amino)pentanoic acid, 5-(Boc-amino)valeric acid
  • 5-(tert-Butoxycarbonylamino)pentanoic Acid N-Boc-5-aminovaleric Acid N-Boc-5-aminopentanoic Acid
  • Boc-d-aMinovaleric acid
  • N-(tert-Butoxycarbonyl)-5-aMinovaleric Acid
  • Boc-5-Ava-OH 97%
  • Boc-2-amino-5-phenylpentanoic acid DCHA
  • <i>N</i>-(<i>tert</i>-Butoxycarbonyl)-5-aminovaleric Acid
  • Boc-5-aminovaleric acid≥ 97% (HPLC)
  • 5-(Boc-amino)valeric AcidN-Boc-5-aminovaleric Acid
  • N-(tert-Butoxycarbonyl)-5-aminop
  • (Tert-Butoxy)Carbonyl 5-Ava-OH
  • N-(tert-Butoxycarbonyl)-5-aminovaleric Acid &gt
  • 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
  • 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoicaci
  • N-(tert-Butoxycarbonyl)-5-aminopentanoic Acid
  • Boc-5-aminopentanoic acid USP/EP/BP
  • tert-butyl 1-phenyl-2,9,12,15-tetraoxaheptadecan-17-oate
  • 5-[[(1,1-Dimethylethoxy)carbonyl]amino]pentanoic acid
  • PROTAC Linkers,Inhibitor,protac,Boc NH C4 acid,inhibit,BocNHC4acid,Boc-NH-C-4-acid,linker
  • 5-(N-BOC-Amino)pentanoic acid
  • 27219-07-4
  • CH33CO2CNHCH24CO2H
  • CARBOXYLIC ACID
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • Specialty Synthesis
  • Linear Core Amino Acids