Cyclopropane-1-carboximidamide hydrochloride

Uses

Product Name: Cyclopropane-1-carboximidamide hydrochloride
CAS No.: 57297-29-7
Chemical Name: Cyclopropane-1-carboximidamide hydrochloride
Synonyms: CYCLOPROPANECARBOXIMIDAMIDE HYDROCHLORIDE;Cyclopropanecarboximidamide;CYCLOPROPYLCARBAMIDINE HYDROCHLORIDE;BUTTPARK 43\57-26;CYCLOPROPYL CARBAMIDINE HCL;cyclopropanecarbamidine, HCl;Cyclopropancecarboxamidine HCl;Cyclopropancecarboxamidine HCI;Cyclopropanecarboximidamide, HCl;Cyclopropaneamidine hydrochloride
CBNumber: CB8387657
Molecular Formula: C4H9ClN2
Formula Weight: 120.58
MOL File: 57297-29-7.mol

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Cyclopropane-1-carboximidamide hydrochloride Property

Melting point:: 123 °C
storage temp.: Inert atmosphere,Room Temperature
Water Solubility: Soluble in water
form: powder to crystal
color: White to Almost white
Sensitive: Hygroscopic
BRN: 4507255
InChI: InChI=1S/C4H8N2.ClH/c5-4(6)3-1-2-3;/h3H,1-2H2,(H3,5,6);1H
InChIKey: JRYOZJIRAVZGMV-UHFFFAOYSA-N
SMILES: C1(C(N)=N)CC1.[H]Cl
CAS DataBase Reference: 57297-29-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-37/39
WGK Germany: 3
Hazard Note: Irritant/Hygroscopic
HazardClass: IRRITANT
HS Code: 29252900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 735647
Product name: Cyclopropaneamidine hydrochloride
Purity: 97%
Packaging: 5g
Price: $26.5
Updated: 2025/07/31

TCI Chemical

Product number: C2344
Product name: Cyclopropanecarboxamidine Hydrochloride
Purity: >98.0%(N)
Packaging: 1g
Price: $25
Updated: 2025/07/31

TCI Chemical

Product number: C2344
Product name: Cyclopropanecarboxamidine Hydrochloride
Purity: >98.0%(N)
Packaging: 5g
Price: $51
Updated: 2025/07/31

TRC

Product number: C992053
Product name: CyclopropanecarboximidamideHydrochloride
Packaging: 1g
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC12149
Product name: Cyclopropancecarboxamidine HCl
Packaging: 25g
Price: $150
Updated: 2021/12/16

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Cyclopropane-1-carboximidamide hydrochloride Chemical Properties,Usage,Production

Uses

Cyproteramidine hydrochloride is a non-selective protease inhibitor that can be used to inhibit the activity of a variety of enzymes.

Chemical Properties

white to light yellow crystal powde

Synthesis

5500-21-0

57297-29-7

The general procedure for the synthesis of cyclopropanecarboxamidine hydrochloride from cyclopropanecarbonitrile is as follows: in a 1 L reactor equipped with thermocouples, underground gas feed lines, hydrogen chloride cylinders, cylinder balancing device, and a nitrogen bubbler, the reactor was first flushed with nitrogen. Cyclopropanecarbonitrile (100 g, 1.5 mol), methanol (48 g, 1.5 mol) and toluene (400 mL) were then added. The reaction mixture was maintained at 15 °C under slight positive nitrogen pressure while anhydrous hydrogen chloride (57 g, 1.55 mol) was slowly added under the surface of the reaction mixture over a period of 2 hours. After addition, the reaction mixture was stirred at 23°C for 16 hours. Nitrogen was bubbled through the reaction mixture below the surface to purge the excess hydrogen chloride while the effluent was expelled through a water scrubber, a process that lasted for 2 hours. The mixture was cooled to 5 °C and then a methanol solution of ammonia (240 mL 7M solution, 1.7 mol) was added over 10 min, during which the temperature was kept below 25 °C. After standing for 1 h, the excess methanol was removed by distillation under reduced pressure. The product obtained was filtered and washed with toluene (100 mL) and finally dried by suction to give 170 g (94% yield) of cyclopropanecarboxamidine hydrochloride as a solid. The 1H NMR (DMSO-J6) data of the product were as follows: δ 8.8 (br s, 4H), 1.84 (m, 1H), 1.1 (m, 4H).

References

[1] Patent: WO2006/121648, 2006, A2. Location in patent: Page/Page column 22-23
[2] Patent: WO2011/58478, 2011, A1. Location in patent: Page/Page column 31
[3] Patent: WO2009/81112, 2009, A2. Location in patent: Page/Page column 113-114
[4] Patent: WO2010/92339, 2010, A1. Location in patent: Page/Page column 83
[5] Patent: US2003/139415, 2003, A1

Cyclopropane-1-carboximidamide hydrochloride Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Ethanol Sodium chloride Toluene Diethyl ether Ammonium chloride Methanol Sodium hydroxide Cyclopropanecarbonitrile Sulfuric acid Ammonia

Preparation Products

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Cyclopropane-1-carboximidamide hydrochloride Suppliers

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View Lastest Price from Cyclopropane-1-carboximidamide hydrochloride manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Cyclopropane-1-carboximidamide HCl 57297-29-7
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-09-08

Career Henan Chemical Co

Product: Cyclopropane-1-carboximidamide hydrochloride 57297-29-7
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

57297-29-7, Cyclopropane-1-carboximidamide hydrochlorideRelated Search:

Formamidine hydrochloride Methyl cyclopropane carboxylate Cyclopropylboronic acid Thiodiazole copper DITHIANON Levomepromazine hydrochloride Topotecan hydrochloride Benzamidine hydrochloride Amitraz 3,3'-Dimethylbenzidine dihydrochloride Cyclopropane Formamidine acetate Cyclopropanecarboxamidoxime,monohydrochloride CYCLOPROPANECARBOXAMIDINE Carboximidamide Cyclopropane-1-carboximidamide hydrochloride

Cyclopropancecarboxamidine HCl

Clcyopropylcarbamidinehydrochloride

Cyclopropylcarbamidinehydrochloride,97%

CYCLOPROPANECARBAMIDINE HYDROCHLORIDE

Cyclopropanecarboximidamide

CYCLOPROPYL CARBAMIDINE HCL

CYCLOPROPYLCARBAMIDINE HYDROCHLORIDE

CYCLOPROPANECARBOXAMIDINE HYDROCHLORIDE

CYCLOPROPANECARBOXIMIDAMIDE HYDROCHLORIDE

CYCLOPROPANE-1-CARBOXIMIDAMIDE HYDROCHLORIDE

BUTTPARK 43\57-26

cyclopropanecarbamidine, HCl

Cyclopropylcarbamidineydrochloride

Cyclopropylcarboxamidine hydrochloride, 97%

Cyclopropane-1-carboxiMidaMide HCl

Cyclopropanecarboximidamide hydrochloride, Carbamimidoylcyclopropane hydrochloride

Cyclopropaneamidine hydrochloride

Cyclopropyl-1-carbamidine hydrochloride

Cyclopropanecarboximidamide, hydrochloride (1:1)

Cyclopropaneamidine hydrochloride≥ 98%(N)

Cyclopropancecarboxamidine HCI

[amino(cyclopropyl)methylidene]ammonium

Cyclopropanecarboxamidine Hydrochloride &gt

Cyclopropanecarboximidamide, HCl

hydrogen cyclopropanecarboximidamide chloride

57297-29-7

C4H9N2

C4H8N2HCl

Cycloalkanes

Ring Systems