ChemicalBook > CAS DataBase List > Tetrahydrothiophen-3-one

Tetrahydrothiophen-3-one

Product Name
Tetrahydrothiophen-3-one
CAS No.
1003-04-9
Chemical Name
Tetrahydrothiophen-3-one
Synonyms
dihydrothiophen-3(2h)-one;Dihydro-3-(2H)-thiophenone;4,5-DIHYDRO-3(2H)-THIOPHENONE;TETRAHYDROTHIOPHENE-3-ONE;FEMA 3266;Tetrahydro-thienone;3-thiolanone;Thiolan-3-one;3-THIOPHANONE;Thiolane-3-one
CBNumber
CB8423034
Molecular Formula
C4H6OS
Formula Weight
102.15
MOL File
1003-04-9.mol
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Tetrahydrothiophen-3-one Property

Boiling point:
175 °C(lit.)
Density 
1.194 g/mL at 25 °C(lit.)
vapor density 
>1 (vs air)
refractive index 
n20/D 1.528(lit.)
FEMA 
3266 | 4,5-DIHYDRO-3(2H)THIOPHENONE
Flash point:
171 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
form 
Liquid
Specific Gravity
1.194
color 
Colorless to pale yellow
Odor
at 0.10 % in dipropylene glycol. garlic meaty green vegetables clams buttery
Odor Type
alliaceous
JECFA Number
498
BRN 
105201
LogP
-0.29
CAS DataBase Reference
1003-04-9(CAS DataBase Reference)
NIST Chemistry Reference
Dihydro-3-(2H)-thiophenone(1003-04-9)
EPA Substance Registry System
3(2H)-Thiophenone, dihydro- (1003-04-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-36/37/39
RIDADR 
UN 3334
WGK Germany 
3
F 
8-13
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W326607
Product name
4,5-Dihydro-3(2H)-thiophenone
Purity
≥98%, FG
Packaging
250g
Price
$745
Updated
2024/03/01
Sigma-Aldrich
Product number
W326607
Product name
4,5-Dihydro-3(2H)-thiophenone
Purity
≥98%, FG
Packaging
1kg
Price
$2800
Updated
2024/03/01
Sigma-Aldrich
Product number
264784
Product name
4,5-Dihydro-3(2H)-thiophenone
Purity
98%
Packaging
25g
Price
$35.4
Updated
2024/03/01
Sigma-Aldrich
Product number
264784
Product name
4,5-Dihydro-3(2H)-thiophenone
Purity
98%
Packaging
5g
Price
$28.8
Updated
2023/06/20
Sigma-Aldrich
Product number
W326607
Product name
4,5-Dihydro-3(2H)-thiophenone
Purity
≥98%, FG
Packaging
25g
Price
$179
Updated
2023/01/07
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Tetrahydrothiophen-3-one Chemical Properties,Usage,Production

Description

Tetrahydro-thiophene-3-one is a heterocyclic nonaromatic ketone. It has a garlic meaty, green vegetable, buttery odor. It is present in cooked beef, coffee, roast filbert, and roasted peanut.
Tetrahydro-thiophene-3-one is used as a food flavoring agent. It is also a valuable organic substance key that opens the synthetic access to numerous derivatives of thiophene.

Chemical Properties

Clear light yellow liquid

Chemical Properties

4,5-Dihydro-3-(2H)thiophenone has a garlic meaty, green vegetable, buttery odor. It is a heterocyclic nonaromatic ketone.

Occurrence

Reported found in cooked beef, coffee, roasted filberts and roasted peanuts.

Uses

4,5-Dihydro-3(2H)-thiophenone is a volatile organic sulfur compound (VOSC) produced by basidiomycetous yeasts.

Uses

Used for blending soft drinks, beverage, meat products, confectionery, and milk product flavors.

Preparation

From 4-methoxycarboxyl-3-oxothiophane treated with 10% sulfuric acid.

Taste threshold values

Taste characteristics at 15 ppm: onion, garlic, cooked meaty with vegetables nuances

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 2229, 1946 DOI: 10.1021/ja01215a034

References

[1] George A. Burdock (2010) Fenaroli's Handbook of Flavor Ingredients, Sixth Edition
[2] https://pubchem.ncbi.nlm.nih.gov
[3] Patent 0127121 A1: Process for the preparation of tetrahydro-thiophen-3-one

Tetrahydrothiophen-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tetrahydrothiophen-3-one manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Tetrahydrothiophen-3-one 1003-04-9
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-11-18
Hebei Weibang Biotechnology Co., Ltd
Product
Tetrahydrothiophen-3-one 1003-04-9
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
JINING XINHE CHEMICAL CO., LTD
Product
Tetrahydrothiophen-3-one 1003-04-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.99%
Supply Ability
10ton
Release date
2024-07-15

1003-04-9, Tetrahydrothiophen-3-oneRelated Search:

Sulfolane Tetrahydrothiophene Thiophene 2-Bromothiophene 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine Tetrahydro-4H-pyran-4-one TETRAHYDROTHIOPYRAN-4-OL 97 1-Tetralone Tetrahydrothiopyran-4-carbaldehyde Tetrahydrofurfuryl alcohol 1,2,3,4-TETRAHYDROISOQUINOLINE TETRAHYDRO-THIOPHEN-3-OL Tetrahydro-2H-thiopyran-4-amine 1,1-Dioxo-tetrahydro-thiopyran-4-one Tetrahydrothiopyran-4-one 2H-Thiopyran-4-methanol, tetrahydro- 2-Thiophenecarboxylic acid, tetrahydro- Tetrahydrothiopyran-4-one oxiMe

  • 3-Oxotetrahydrothiophene
  • 3-Thiacyclopentanone
  • dihydro-3(2h)-thiophenon
  • Dihydro-3-Thiophenone
  • Thiolan-3-one
  • 4,5-DIHYDRO-3(2H)-THIOPHENONE
  • 3-THIOPHANONE
  • dihydrothiophen-3(2h)-one
  • DIHYDRO-THIOPHEN-3-ONE
  • Dihydro-3-(2H)-thiophenone
  • FEMA 3266
  • TETRAHYDRO-3-THIOPHENONE
  • TETRAHYDROTHIOPHENE-3-ONE
  • TETRAHYDROTHIOPHEN-3-ONE
  • TIMTEC-BB SBB007947
  • 4 5-DIHYDRO-3(2H)THIOPHENONE 98+%
  • Tetrahydrothiophen-3-one, 97+%
  • Tetrahydro-thienone
  • 4,5-Dihydro-3(2H)-thiophenone≥ 99% (GC)
  • 3-thiolanone
  • 3-Thiophanone, Tetrahydrothiophen-3-one
  • 3(2H)-dihydrothiophenone
  • 3(2H)-Thiophenone, dihydro-
  • 3’-Tetrahydrothiophenone
  • 3-Oxo-2,3,4,5-tetrahydrothiophene
  • 4,5-Dihydrothiophen-3(2H)-one
  • Thiolane-3-one
  • Tetrahydrothiophene-3-one 3-Thiophanone
  • 1,2,3,4-tetrahydrothiophen-3-one
  • Thiolan-3-onedihydrothiophen-3(2h)-one
  • Tetrahydrothiophen-3-one >=98.0%
  • 3-Oxotetrahydrothiophene, Thiolan-3-one, 3-Oxothiolane
  • Fourtetrahydro thiophene-3- ketone
  • Tetrahydrothiophen-3-one, 98%, 98%
  • Tetrahydrothiophe<i>N</i>-3-one
  • 4,5-Dihydro-3(2H)-thiophenone 98%
  • 4,5-Dihydro-3(2H)-thiophenone&gt
  • etrahydrothiophen-3-one
  • Tetrahydrothiophene 3-1
  • Tetrahydrothiophen-3-one USP/EP/BP
  • Tetrohydro Thienone
  • High Quality Tetrahydrothiophen-3-One CAS 1003-04-9
  • High purity CAS 1003-04-9 Tetrahydrothiophen-3-one in stock
  • Phenylacetaldehyde 122-78-1
  • 4,5-Dihydro-3-(2H)-thiophenone(Tetrahydrothiophen-3-One)
  • Tetrahydrothiophen 3 one,Tetrahydrothiophen3one
  • Thiophene-3-ketone
  • 1003-04-9
  • 63996-36-2
  • 1003-04-09
  • C4H6OS
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  • Heterocyclic Building Blocks
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  • Thiophene&Benzothiophene
  • thiophene Flavor
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