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ChemicalBook > CAS DataBase List > 2-Amino-4-chloro-3-nitropyridine

2-Amino-4-chloro-3-nitropyridine

Description Reference
Product Name
2-Amino-4-chloro-3-nitropyridine
CAS No.
6980-08-1
Chemical Name
2-Amino-4-chloro-3-nitropyridine
Synonyms
4-Chloro-3-nitropyridin-2-amine;0/1/80;2-AMINO-4-CHLORO-3-NITROPYRIDINE;2-PyridinaMine, 4-chloro-3-nitro-;4-Chloro-3-nitro-pyridin-2-ylaMine;2-Amino-4-chloro-3-nitropyridine ISO 9001:2015 REACH
CBNumber
CB8445690
Molecular Formula
C5H4ClN3O2
Formula Weight
173.56
MOL File
6980-08-1.mol
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2-Amino-4-chloro-3-nitropyridine Property

Melting point:
174-176°C
Boiling point:
329.0±37.0 °C(Predicted)
Density 
1.596±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Soluble in dimethyl formamide, dimethyl sulfoxide, hot ethanol, ethyl acetate and hot methanol.
pka
1.31±0.47(Predicted)
form 
Solid
color 
Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H64678
Product name
2-Amino-4-chloro-3-nitropyridine, 95%
Packaging
1g
Price
$76.65
Updated
2024/03/01
Alfa Aesar
Product number
H64678
Product name
2-Amino-4-chloro-3-nitropyridine, 95%
Packaging
5g
Price
$279.65
Updated
2024/03/01
Alfa Aesar
Product number
H64678
Product name
2-Amino-4-chloro-3-nitropyridine, 95%
Packaging
250mg
Price
$33.5
Updated
2023/06/20
TRC
Product number
A603485
Product name
2-Amino-4-chloro-3-nitropyridine
Packaging
50mg
Price
$105
Updated
2021/12/16
Usbiological
Product number
A1376-52
Product name
2-Amino-4-chloro-3-nitropyridine
Packaging
100mg
Price
$460
Updated
2021/12/16
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2-Amino-4-chloro-3-nitropyridine Chemical Properties,Usage,Production

Description

It is usually used as the intermediate or raw material in organic synthesis and pharmaceutical industry. Specifically, this chemical can act as the intermediate in the synthesis of 5-amino-azaoxindole derivatives.1 Moreover, this substance may be involved in the preparation of pharmaceutically active compounds that can be used in the treatment of proliferative disorders, as well as other diseases or conditions in which aurora kinase and/or FLT3 activity is implicated.2 In addition, this chemical has been demonstrated to function as the intermediate in the synthesis of 1-deaza-6-methylthiopurine ribonucleoside, which is proved to exhibit cytotoxicty.3 Besides, 2-amino-4-chloro-3-nitropyridine can be utilized to fabricate central nervous system (CNS) active compounds.4

Reference

  1. Tzvetkov, N. T.; Muller, C. E., Facile synthesis of 5-aminoand 7-amino-6-azaoxindole derivatives. Tetrahedron Lett. 2012, 53, 5597-5601.
  2. Julian Blagg; Bavetsias; Moore; Linardopoulos, pharmaceutically active compounds. US Patent US 9447092 B2 2016.
  3. JMontgomery, J. A.; Hewson, K., 1-DEAZA-6-METHYLTHIOPURINE RIBONUCLEOSIDE. J. Med. Chem. 1966, 9, 354-+.
  4. JHarry Louis Yale; Sheehan, J. T., CNS active compounds US Patent 4022897 1977.

Chemical Properties

Bright Yellow Needles

Uses

2-Amino-4-chloro-3-nitropyridine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

2-Amino-4-chloro-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-4-chloro-3-nitropyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Amino-4-chloro-3-nitropyridine 6980-08-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Shaanxi Dideu Medichem Co. Ltd
Product
2-AMino-4-chloro-3-nitropyridine 6980-08-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2019-12-27
Dideu Industries Group Limited
Product
2-Amino-4-chloro-3-nitropyridine 6980-08-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-03

6980-08-1, 2-Amino-4-chloro-3-nitropyridineRelated Search:


  • 2-AMINO-4-CHLORO-3-NITROPYRIDINE
  • 4-Chloro-3-nitropyridin-2-amine
  • 4-Chloro-3-nitro-pyridin-2-ylaMine
  • 2-PyridinaMine, 4-chloro-3-nitro-
  • 2-Amino-4-chloro-3-nitropyridine ISO 9001:2015 REACH
  • 0/1/80
  • 6980-08-1
  • 8/1/6980
  • 6980-8-1
  • 6980-08-6
  • 6980/8/1
  • 6980-80-1
  • 60.980-08-1
  • Heterocycle-Pyridine series
  • Amines
  • Aromatics
  • Heterocycles
  • Pyridines
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides
  • API intermediates