2-Amino-4-chloro-3-nitropyridine
Description Reference- Product Name
- 2-Amino-4-chloro-3-nitropyridine
- CAS No.
- 6980-08-1
- Chemical Name
- 2-Amino-4-chloro-3-nitropyridine
- Synonyms
- 4-Chloro-3-nitropyridin-2-amine;0/1/80;2-AMINO-4-CHLORO-3-NITROPYRIDINE;2-PyridinaMine, 4-chloro-3-nitro-;4-Chloro-3-nitro-pyridin-2-ylaMine;2-Amino-4-chloro-3-nitropyridine ISO 9001:2015 REACH
- CBNumber
- CB8445690
- Molecular Formula
- C5H4ClN3O2
- Formula Weight
- 173.56
- MOL File
- 6980-08-1.mol
2-Amino-4-chloro-3-nitropyridine Property
- Melting point:
- 174-176°C
- Boiling point:
- 329.0±37.0 °C(Predicted)
- Density
- 1.596±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Soluble in dimethyl formamide, dimethyl sulfoxide, hot ethanol, ethyl acetate and hot methanol.
- pka
- 1.31±0.47(Predicted)
- form
- Solid
- color
- Yellow
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H64678
- Product name
- 2-Amino-4-chloro-3-nitropyridine, 95%
- Packaging
- 1g
- Price
- $76.65
- Updated
- 2024/03/01
- Product number
- H64678
- Product name
- 2-Amino-4-chloro-3-nitropyridine, 95%
- Packaging
- 5g
- Price
- $279.65
- Updated
- 2024/03/01
- Product number
- H64678
- Product name
- 2-Amino-4-chloro-3-nitropyridine, 95%
- Packaging
- 250mg
- Price
- $33.5
- Updated
- 2023/06/20
- Product number
- A603485
- Product name
- 2-Amino-4-chloro-3-nitropyridine
- Packaging
- 50mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- A1376-52
- Product name
- 2-Amino-4-chloro-3-nitropyridine
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
2-Amino-4-chloro-3-nitropyridine Chemical Properties,Usage,Production
Description
It is usually used as the intermediate or raw material in organic synthesis and pharmaceutical industry. Specifically, this chemical can act as the intermediate in the synthesis of 5-amino-azaoxindole derivatives.1 Moreover, this substance may be involved in the preparation of pharmaceutically active compounds that can be used in the treatment of proliferative disorders, as well as other diseases or conditions in which aurora kinase and/or FLT3 activity is implicated.2 In addition, this chemical has been demonstrated to function as the intermediate in the synthesis of 1-deaza-6-methylthiopurine ribonucleoside, which is proved to exhibit cytotoxicty.3 Besides, 2-amino-4-chloro-3-nitropyridine can be utilized to fabricate central nervous system (CNS) active compounds.4
Reference
- Tzvetkov, N. T.; Muller, C. E., Facile synthesis of 5-aminoand 7-amino-6-azaoxindole derivatives. Tetrahedron Lett. 2012, 53, 5597-5601.
- Julian Blagg; Bavetsias; Moore; Linardopoulos, pharmaceutically active compounds. US Patent US 9447092 B2 2016.
- JMontgomery, J. A.; Hewson, K., 1-DEAZA-6-METHYLTHIOPURINE RIBONUCLEOSIDE. J. Med. Chem. 1966, 9, 354-+.
- JHarry Louis Yale; Sheehan, J. T., CNS active compounds US Patent 4022897 1977.
Chemical Properties
Bright Yellow Needles
Uses
2-Amino-4-chloro-3-nitropyridine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
2-Amino-4-chloro-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-4-chloro-3-nitropyridine manufacturers
- Product
- 2-Amino-4-chloro-3-nitropyridine 6980-08-1
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2-AMino-4-chloro-3-nitropyridine 6980-08-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2019-12-27
- Product
- 2-Amino-4-chloro-3-nitropyridine 6980-08-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-03