ChemicalBook > CAS DataBase List > 2-Amino-5-fluoropyridine

2-Amino-5-fluoropyridine

Product Name
2-Amino-5-fluoropyridine
CAS No.
21717-96-4
Chemical Name
2-Amino-5-fluoropyridine
Synonyms
5-FLUOROPYRIDIN-2-AMINE;2-Amino-5-fL;Risdiplam Impurity 13;Amino-5-fluoropyridine;5-FLUORO-2-PYRIDINAMINE;5-fluoro-2-aminepyridin;5-FLUORO-2-AMINOPYRIDINE;2-Amino-5-fluoropyridine;2-Amine-5-fluoropyridine;2-Amino-5-fluoroypyridine
CBNumber
CB8471590
Molecular Formula
C5H5FN2
Formula Weight
112.11
MOL File
21717-96-4.mol
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2-Amino-5-fluoropyridine Property

Melting point:
93-97 °C (lit.)
Boiling point:
125 °C
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
4.62±0.13(Predicted)
form 
Powder
color 
White to orange
BRN 
385938
InChI
InChI=1S/C5H5FN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey
YJTXQLYMECWULH-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(F)C=C1
CAS DataBase Reference
21717-96-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
26-36-45-36/37/39-27
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
518689
Product name
2-Amino-5-fluoropyridine
Purity
97%
Packaging
1g
Price
$35.04
Updated
2024/03/01
Sigma-Aldrich
Product number
518689
Product name
2-Amino-5-fluoropyridine
Purity
97%
Packaging
5g
Price
$230
Updated
2023/06/20
TCI Chemical
Product number
A1664
Product name
2-Amino-5-fluoropyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$58
Updated
2024/03/01
TCI Chemical
Product number
A1664
Product name
2-Amino-5-fluoropyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$173
Updated
2024/03/01
Alfa Aesar
Product number
L20010
Product name
2-Amino-5-fluoropyridine, 97%
Packaging
1g
Price
$95.65
Updated
2024/03/01
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2-Amino-5-fluoropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Amino-5-fluoropyridine is used in chemical microarrays to identify ligands that binds pathogenic cells. Acts as a reagent in the preparation of heterocyclic compounds as integrase inhibiting antiviral agents.

Definition

ChEBI: 2-Amino-5-fluoropyridine is a dihydropyridine.

Synthesis

2-Amino-5-fluoropyridine is an important intermediate for the synthesis of LBM415 which is the peptide deformylas inhibitor. Using 2-aminopyridine as raw material and via nitrification, amino acetylation, reduction of nitro, diazolization, Schiemann reaction and hydrolysis of acetyl.

References

[1] E. S. HAND, D. C. BAKER. “ChemInform Abstract: Syntheses of 2-Chloro- and 2-Amino-5-fluoropyridines and Isolation of a Novel Difluoroboryl Imidate.” ChemInform 21 19 (1990).

2-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials

Xylene Isoamyl nitrite Ethanol Acetic anhydride 2-Amino-5-nitropyridine Palladium Fluoroboric acid Benzene

Preparation Products

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2-Amino-5-fluoropyridine Suppliers

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View Lastest Price from 2-Amino-5-fluoropyridine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Amino-5-fluoropyridine 21717-96-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-20
Hebei Mujin Biotechnology Co.,Ltd
Product
2-Amino-5-fluoropyridine 21717-96-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-30
Hebei Weibang Biotechnology Co., Ltd
Product
2-Amino-5-fluoropyridine 21717-96-4
Price
US $8.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28

21717-96-4, 2-Amino-5-fluoropyridineRelated Search:

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  • 5-FLUORO-2-PYRIDINAMINE
  • 5-FLUOROPYRIDIN-2-AMINE
  • 5-FLUORO-PYRIDIN-2-YL-AMINE
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  • 2-AMINO-5-FLUOROPYRIDINE, 98+%
  • 2-AMINO-5-FLUOROPYRIDINE 5-FLUORO-PYRIDIN-2-YLAMINE
  • 2-Amino-5-fL
  • 2-Amino-5-fluoropyridine ,97%
  • 2-Amino-5-fluoropyridine
  • 5-fluoro-2-aminepyridin
  • Pyridine, 2-aMino-5-fluoro- (8CI)
  • 2-aMino-5-fluoride pyridine
  • (5-fluoro-2-pyridyl)amine
  • 2-Amino-5-fluoropyridine &gt
  • 2-Pyridinamine, 5-fluoro-
  • 2-Amino-5-fluoropyridine ISO 9001：2015 REACH
  • 2-Amine-5-fluoropyridine
  • Amino-5-fluoropyridine
  • Risdiplam Impurity 13
  • 21717-96-4
  • 152043-90-3
  • 2171-96-4
  • 504-29-8
  • Halopyridines
  • Fluoropyridines
  • Building Blocks
  • C5
  • Pyridines
  • Heterocyclic Building Blocks
  • Boronic Acid
  • C5
  • Heterocyclic Building Blocks
  • Fluorine series
  • Amino-pyridine series
  • blocks
  • FluoroCompounds
  • Heterocycles
  • Pyridines
  • Pyridine
  • Pyridine series
  • Pyridines derivates
  • Fluorin-contained pyridine series
  • Fluoropyridines
  • Halopyridines