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DMT-2′Fluoro-dU Phosphoramidite

Product Name
DMT-2′Fluoro-dU Phosphoramidite
CAS No.
146954-75-8
Chemical Name
DMT-2′Fluoro-dU Phosphoramidite
Synonyms
2‘-F-U amidite;2'-Fluoro-dU CEP;2’-F-dU Amidite;2’-F-rUPhosphoramidite;2'-F-U Phosphoramidite;2'-F-dU Phosphoramidite;5'-O-DMT-2'-fluoro-dU-CE;5'-O-DMT-2'-F-dU-3'-CEDPA;2'-Fluoro Uridine Amidite;DMT-2'-F-U Phosphoramidite
CBNumber
CB8500324
Molecular Formula
C39H46FN4O8P
Formula Weight
748.78
MOL File
146954-75-8.mol
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DMT-2′Fluoro-dU Phosphoramidite Property

storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
powder
pka
9.39±0.10(Predicted)
color 
white to off-white
InChI
InChI=1/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-24-10-22-41)52-36-33(51-37(35(36)40)43-23-21-34(45)42-38(43)46)25-49-39(28-11-8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-30/h7-9,11-21,23,26-27,33,35-37H,10,24-25H2,1-6H3,(H,42,45,46)/t33-,35-,36-,37-,53?/s3
InChIKey
HQHQPAYRJJMYQX-YOKGOYKLNA-N
SMILES
N1(C=CC(=O)NC1=O)[C@@H]1O[C@H](COC(C2=CC=CC=C2)(C2C=CC(=CC=2)OC)C2=CC=C(C=C2)OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]1F |&1:8,10,36,51,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U211280
Product name
DMT-2′Fluoro-dU Phosphoramidite
Purity
configured for PerkinElmer, configured for Polygen
Packaging
1G
Price
$206
Updated
2024/03/01
Sigma-Aldrich
Product number
U211250
Product name
DMT-2′Fluoro-dU Phosphoramidite
Purity
configured for (?KTA? and OligoPilot?)
Packaging
1G
Price
$219
Updated
2024/03/01
Sigma-Aldrich
Product number
U211200
Product name
DMT-2′Fluoro-dU Phosphoramidite
Purity
≥99% (31P-NMR)
Packaging
100g
Price
$8200
Updated
2024/03/01
Sigma-Aldrich
Product number
U211200
Product name
DMT-2′Fluoro-dU Phosphoramidite
Purity
≥99% (31P-NMR)
Packaging
500g
Price
$36650
Updated
2024/03/01
Sigma-Aldrich
Product number
U211280
Product name
DMT-2′Fluoro-dU Phosphoramidite
Purity
configured for PerkinElmer, configured for Polygen
Packaging
2g
Price
$383
Updated
2024/03/01
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DMT-2′Fluoro-dU Phosphoramidite Chemical Properties,Usage,Production

Uses

5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidite (DMT-2′Fluoro-dU Phosphoramidite) is a uridine phosphoramidite consisting of a fluorine in the 2' position, and the compound is used in the synthesis of DNA.

Definition

DMT-2′Fluoro-dU Phosphoramidite is also known as 2'-F-U CE-Phosphoramidite. 2'-F-RNA oligonucleotides adopt an A-form helix on hybridisation to a target. Whereas a hydroxyl group of RNA is a hydrogen bond donor, fluorine appears to be a weak acceptor. These features of 2'-F-RNA oligonucleotides lead to certain interesting properties. For example, it was demonstrated that oligonucleotides hybridise to a RNA oligonucleotide in the following order of increasing stability: DNA < RNA < 2'-OMe-RNA < 2'-F-RNA

DMT-2′Fluoro-dU Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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DMT-2′Fluoro-dU Phosphoramidite Suppliers

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View Lastest Price from DMT-2′Fluoro-dU Phosphoramidite manufacturers

R&D Scientific Inc.
Product
5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidit 146954-75-8
Price
US $1550.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-02-10
SHANGHAI NOVRIBO BIOTECH
Product
2'-F-dU CE Phosphoramidite 146954-75-8
Price
US $100.00/kg
Min. Order
0.009999999776482582kg
Purity
99%
Supply Ability
5tons
Release date
2023-03-21
Hefei Huana Biomedical Technology Co.,Ltd.
Product
5'-O-DMT-2'-fluoro-dU-CE 146954-75-8
Price
US $0.00/mg
Min. Order
100mg
Purity
≥99%
Supply Ability
20tons
Release date
2023-03-09

146954-75-8, DMT-2′Fluoro-dU PhosphoramiditeRelated Search:

3-Chloropropyltrimethoxysilane Doxifluridine 1-beta-D-Arabinofuranosyluracil Pseudouridine 3-Chloropropyltriethoxysilane 3-Aminopropyltriethoxysilane Floxuridine 5-Fluorouridine DMT-dG(ib) Phosphoramidite DMT-dA(bz) Phosphoramidite DMT-2'O-Methyl-rU Phosphoramidite DMT-2'O-TBDMS-rA(bz) Phosphoramidite DMT-dG(dmf) Phosphoramidite 3'-TBDMS-ibu-rG Phosphoramidite Ac-rC Phosphoramidite Uridine DMT-2′Fluoro-dU Phosphoramidite

  • 3-({[(2-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-5-(2,4-DIOXO-3H-PYRIMIDIN-1-YL)-4-FLUOROOXOLAN
  • 2'-Fluoro-5'-O-DMT-2'-deoxyuridine-3'-CE-Phosphoramidite
  • 5'-DMT-2'-F-rU Phosphoramidite
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
  • 2'-Deoxy-2'-fluoro-5'-O-DMT-Uridine Phosphoramidite
  • DMT-2'-F-DU AMIDITE 0.25G, AB, SINGLE
  • DMT-2'-F-dU Amidite 0.25g, 89, Single
  • 2’-F-rUPhosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-F-dU-3'-CEDPA
  • 2'-F-dU Phosphoramidite
  • 2'-Deoxy-2'-fluoro-5'-O-DMT-Uridine-3'-CED PhosphoraMidite
  • DMT-2′Fluoro-dU Phosphoramidite
  • 5'-O-DMT-2'-Fluoro-2'-deoxyuridine 3'-CE phosphoramidite
  • 2'-Fluoro-dU CEP
  • Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • 5'-Dimethoxytrityl-deoxyUridine, 2'-fluoro-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 2'-Fluoro-N2-Isobutyryl-5'-O-DMT-2'-Deoxyguanosine-3'-CE-Phosphoramidite
  • 5'-DMTr-2'-F-3'-O-CEP-URIDINE
  • 5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidite
  • 5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidit
  • 2‘-F-U amidite
  • DMT-2'-F-U Phosphoramidite
  • DMT-2’-F-dU-CE Phosphoramidite
  • 5'-O-DMT-2'-fluoro-dU-CE
  • Inhibitor,Nucleoside Antimetabolite/Analog,DMT2′FluorodU Phosphoramidite,inhibit,DMT 2′Fluoro dU Phosphoramidite
  • 5'-O-DMT-2'-F-2'-Deoxy Uridine -3’-Cyanoethyl Phosphoramidite
  • 2'-Fluoro Uridine Amidite
  • 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-tetrahydrofuran-3-yl]oxy-(diisopropylamino)phosphanyl]oxypropanenitrile
  • DMTr-2'-F-dU-3'-CE-Phosphoramidite
  • 2’-F-dU Amidite
  • 5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyuridine-3'-CE-Phosphoramidite
  • 5'-ODMT-2'-Fluoro uridine-3'-OCEPA
  • 2'-F-U Phosphoramidite
  • DMT-2'-F-dU-CE Phosphoramidite
  • 5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
  • 5'-O-DMT-2'-F-Deoxyuridine-CE Phosphoramidit
  • 146954-75-8
  • Amidite