ChemicalBook > CAS DataBase List > NOURSEOTHRICIN SULFATE

NOURSEOTHRICIN SULFATE

Product Name
NOURSEOTHRICIN SULFATE
CAS No.
96736-11-7
Chemical Name
NOURSEOTHRICIN SULFATE
Synonyms
STREPTOTHRICIN;NOURSEOTHRICIN SULFATE;Streptothricin sulfate;NOURSEOTHRICIN SULPHATE;UDVWKDBCMFLRQW-TWRCRAKCSA-N;NOURSEOTHRICIN SULFATE 90+%;nourseothricin,sulfate(salt);Nourseothricin (NTC) Sulfate;Nourseothricin (streptothricin) sulfate;Nourseothricin Sulfate (Streptothricin Sulfate)
CBNumber
CB8667052
Molecular Formula
C44H82N18O21S
Formula Weight
1231.29488
MOL File
96736-11-7.mol
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NOURSEOTHRICIN SULFATE Property

storage temp. 
2-8°C
solubility 
H2O: soluble200mg/mL
form 
solid
color 
white to light brown
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
RD4240000
10
HS Code 
2941900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
74667
Product name
Nourseothricin sulfate
Purity
≥85% (HPLC)
Packaging
10mg
Price
$301
Updated
2024/03/01
Sigma-Aldrich
Product number
74667
Product name
Nourseothricin sulfate
Purity
≥85% (HPLC)
Packaging
100mg
Price
$2190
Updated
2024/03/01
Alfa Aesar
Product number
H37154
Product name
Nourseothricin sulfate
Packaging
100mg
Price
$163
Updated
2024/03/01
Alfa Aesar
Product number
H37154
Product name
Nourseothricin sulfate
Packaging
1g
Price
$906
Updated
2024/03/01
Cayman Chemical
Product number
16227
Product name
Nourseothricin (sulfate)
Packaging
1mg
Price
$32
Updated
2024/03/01
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NOURSEOTHRICIN SULFATE Chemical Properties,Usage,Production

Uses

Streptothricin sulfate is a broad spectrum antibacterial compound with antiviral activity.

Biological Activity

nourseothricin is a broad-spectrum antibiotic.nourseothricin is a broad-spectrum antibiotic derived from streptomyces noursei.

in vitro

nourseothricin, represents a mixture of streptothricins, mainly d and f. although very slowly, nourseothricin was found to be able to pass the outer membrane through the porin pores. it has been also shown that nourseothricin was able to generate some channels into the outer membrane. moreover, resistant strains containing a streptothricin-inactivating acetyl transferase exhibited an additional protecting system, namely a reduced penetrability of the outer membrane. in addition, such strains indeed could be rendered sensitive via damaging the barrier function of the outer membrane [1].

in vivo

animal study showed that nourseothricin was preferentially excreted via kidney and signs of nephrotoxicity could be seen. renal handling of nourseothricin was characterized on renal cortical slices under various experimental conditions. following administration the renal tubular transport system for organic anions was not influenced by nourseothricin. there was a high degree of accumulation of nourseothricin in renal cortical slices. in contrast to pah accumulation, there was no influence of nitrogen atmosphere, probenecid or trishydroxyaminomethane on nourseothricin accumulation. age dependent differences in nourseothricin accumulation did not exist [2].

References

[1] seltmann g. resistance of escherichia coli to nourseothricin (streptothricin): sensitization of resistant strains by abolition of its outer membrane resistance. zentralbl bakteriol. 1992 jan;276(2):143-51.
[2] brunlich h, hoffmann h, bocker h. renal handling of nourseothricin. pharmazie. 1988 mar;43(3):200-2.

NOURSEOTHRICIN SULFATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NOURSEOTHRICIN SULFATE manufacturers

Career Henan Chemical Co
Product
NOURSEOTHRICIN SULFATE 96736-11-7
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

96736-11-7, NOURSEOTHRICIN SULFATERelated Search:


  • STREPTOTHRICIN
  • NOURSEOTHRICIN SULFATE
  • NOURSEOTHRICIN SULPHATE
  • nourseothricin,sulfate(salt)
  • NOURSEOTHRICIN SULFATE 90+%
  • Streptothricin sulfate
  • Nourseothricin (streptothricin) sulfate
  • UDVWKDBCMFLRQW-TWRCRAKCSA-N
  • [5-(3,6-diaminohexanoylamino)-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate
  • [5-[[3-amino-6-(3,6-diaminohexanoylamino)hexanoyl]amino]-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate
  • Nourseothricin Sulfate (Streptothricin Sulfate)
  • Nourseothricin (NTC) Sulfate
  • Inhibitor,Streptothricin,Fungal,Nourseothricin sulfate,Bacterial,Antibiotic,Nourseothricin,inhibit
  • (5ξ)-4-O-Carbamoyl-2-deoxy-2-{[(3S)-3,6-diaminohexanoyl]amino}-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-α-L-lyxo-hexopyranosylamine
  • 96736-11-7
  • C44H82N18O21S
  • C31H58N12O10C19H34N8O8H2SO4
  • Antibiotics N-S
  • Antibiotics A to Z
  • Antibiotics
  • BioChemical