NOURSEOTHRICIN SULFATE
- Product Name
- NOURSEOTHRICIN SULFATE
- CAS No.
- 96736-11-7
- Chemical Name
- NOURSEOTHRICIN SULFATE
- Synonyms
- STREPTOTHRICIN;NOURSEOTHRICIN SULFATE;Streptothricin sulfate;NOURSEOTHRICIN SULPHATE;UDVWKDBCMFLRQW-TWRCRAKCSA-N;NOURSEOTHRICIN SULFATE 90+%;nourseothricin,sulfate(salt);Nourseothricin (NTC) Sulfate;Nourseothricin (streptothricin) sulfate;Nourseothricin Sulfate (Streptothricin Sulfate)
- CBNumber
- CB8667052
- Molecular Formula
- C44H82N18O21S
- Formula Weight
- 1231.29488
- MOL File
- 96736-11-7.mol
NOURSEOTHRICIN SULFATE Property
- storage temp.
- 2-8°C
- solubility
- H2O: soluble200mg/mL
- form
- solid
- color
- white to light brown
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- RD4240000
- F
- 10
- HS Code
- 2941900000
N-Bromosuccinimide Price
- Product number
- 74667
- Product name
- Nourseothricin sulfate
- Purity
- ≥85% (HPLC)
- Packaging
- 10mg
- Price
- $301
- Updated
- 2024/03/01
- Product number
- 74667
- Product name
- Nourseothricin sulfate
- Purity
- ≥85% (HPLC)
- Packaging
- 100mg
- Price
- $2190
- Updated
- 2024/03/01
- Product number
- H37154
- Product name
- Nourseothricin sulfate
- Packaging
- 100mg
- Price
- $163
- Updated
- 2024/03/01
- Product number
- H37154
- Product name
- Nourseothricin sulfate
- Packaging
- 1g
- Price
- $906
- Updated
- 2024/03/01
- Product number
- 16227
- Product name
- Nourseothricin (sulfate)
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
NOURSEOTHRICIN SULFATE Chemical Properties,Usage,Production
Uses
Streptothricin sulfate is a broad spectrum antibacterial compound with antiviral activity.
Biological Activity
nourseothricin is a broad-spectrum antibiotic.nourseothricin is a broad-spectrum antibiotic derived from streptomyces noursei.
in vitro
nourseothricin, represents a mixture of streptothricins, mainly d and f. although very slowly, nourseothricin was found to be able to pass the outer membrane through the porin pores. it has been also shown that nourseothricin was able to generate some channels into the outer membrane. moreover, resistant strains containing a streptothricin-inactivating acetyl transferase exhibited an additional protecting system, namely a reduced penetrability of the outer membrane. in addition, such strains indeed could be rendered sensitive via damaging the barrier function of the outer membrane [1].
in vivo
animal study showed that nourseothricin was preferentially excreted via kidney and signs of nephrotoxicity could be seen. renal handling of nourseothricin was characterized on renal cortical slices under various experimental conditions. following administration the renal tubular transport system for organic anions was not influenced by nourseothricin. there was a high degree of accumulation of nourseothricin in renal cortical slices. in contrast to pah accumulation, there was no influence of nitrogen atmosphere, probenecid or trishydroxyaminomethane on nourseothricin accumulation. age dependent differences in nourseothricin accumulation did not exist [2].
References
[1] seltmann g. resistance of escherichia coli to nourseothricin (streptothricin): sensitization of resistant strains by abolition of its outer membrane resistance. zentralbl bakteriol. 1992 jan;276(2):143-51.
[2] brunlich h, hoffmann h, bocker h. renal handling of nourseothricin. pharmazie. 1988 mar;43(3):200-2.
NOURSEOTHRICIN SULFATE Preparation Products And Raw materials
Raw materials
Preparation Products
NOURSEOTHRICIN SULFATE Suppliers
View Lastest Price from NOURSEOTHRICIN SULFATE manufacturers
- Product
- NOURSEOTHRICIN SULFATE 96736-11-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25