ChemicalBook > CAS DataBase List > Triphenylmethyl Chloride

Triphenylmethyl Chloride

Product Name
Triphenylmethyl Chloride
CAS No.
76-83-5
Chemical Name
Triphenylmethyl Chloride
Synonyms
TRT-CL;TRITYL CHLORIDE;(ChloroMethanetriyl)tribenzene;CHLOROTRIPHENYLMETHANE;TRIPHENYLCHLOROMETHANE;[Chloro(diphenyl)methyl]benzene;TRITY CHLORIDE;TRIPHENYLCHLORMETHANE;chlorotriphenyl-methan;NSC 435
CBNumber
CB8669405
Molecular Formula
C19H15Cl
Formula Weight
278.78
MOL File
76-83-5.mol
More
Less

Triphenylmethyl Chloride Property

Melting point:
109-112 °C(lit.)
Boiling point:
230-235 °C20 mm Hg(lit.)
Density 
1.1088 (rough estimate)
refractive index 
1.6281 (estimate)
Flash point:
230-235°C/20mm
storage temp. 
Store below +30°C.
solubility 
chloroform: 0.1 g/mL, clear
form 
Powder or Crystals
color 
White to off-white or light yellow-beige
Water Solubility 
Insoluble in water. Soluble in chloroform, hexane, benzene, ether, acetone and tetrahydrofuran.
Sensitive 
Lachrymatory
BRN 
397363
CAS DataBase Reference
76-83-5(CAS DataBase Reference)
NIST Chemistry Reference
Triphenylmethyl chloride(76-83-5)
EPA Substance Registry System
Chlorotriphenylmethane (76-83-5)
More
Less

Safety

Hazard Codes 
C,N
Risk Statements 
34-50/53-14-36/37
Safety Statements 
26-36/37/39-45-61-27
RIDADR 
UN 3261 8/PG 3
WGK Germany 
3
RTECS 
PA6450000
F 
10-19-21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29036990
Hazardous Substances Data
76-83-5(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 5000 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
93000
Product name
Trityl chloride
Purity
purum, ≥97.0% (HPLC), ≥97.0% (AT)
Packaging
100g
Price
$50.7
Updated
2024/03/01
Sigma-Aldrich
Product number
93000
Product name
Trityl chloride
Purity
purum, ≥97.0% (HPLC), ≥97.0% (AT)
Packaging
5kg
Price
$1520
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08348
Product name
Chlorotriphenylmethane
Purity
for synthesis
Packaging
250g
Price
$67.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08348
Product name
Chlorotriphenylmethane
Purity
for synthesis
Packaging
1kg
Price
$264
Updated
2024/03/01
TCI Chemical
Product number
C0308
Product name
Trityl Chloride
Purity
>98.0%(T)
Packaging
25g
Price
$23
Updated
2024/03/01
More
Less

Triphenylmethyl Chloride Chemical Properties,Usage,Production

Chemical Properties

Triphenylmethyl chloride or trityl chloride (TrCl) is a white to yellow solid. Insoluble in water, easily soluble in benzene, carbon disulfide, petroleum ether, slightly soluble in alcohol and ether, and becomes trityl alcohol after absorbing water. It is an alkyl halide, sometimes used to introduce the trityl protecting group.

Uses

Trityl Chloride is an alkyl halide commonly used in organic synthesis to introduce the trityl protecting group. Trityl Chloride is used in the preparation of S-trityl-L-cysteine (STLC), a tight-bindin g inhibitor of Eg5 that prevents mitotic progression.

Application

Triphenylmethyl Chloride acts as a protecting reagent for amines, alcohols, and thiols. It can be used as a catalyst:
Efficient method of tritylation of sensitive compounds and their subsequent detritylation.
In Ritter type synthesis of 1-amidoalkyl-2-naphtols through a one-pot three-component reaction of naphthol, aryl aldehydes and acetonitrile.
In the synthesis of 1,2,4,5-tetrasubstituted imidazoles via a one-pot multi-component reaction of benzil with aldehydes, primary amines, and ammonium acetate.
In the preparation of amido alkyl phenols via one-pot, multi-component reaction of phenols, aromatic aldehydes, and amides under solvent-free conditions.
In one-pot, multi-component synthesis of substituted piperidines using aromatic aldehydes, amines, and β-ketoesters.

Preparation

Triphenylmethyl Chloride may be prepared by the reaction of triphenylmethanol with acetyl chloride, or by the Friedel–Crafts alkylation of benzene with carbon tetrachloride to give the trityl chloride-aluminium chloride adduct, which is then hydrolyzed.

Purification Methods

Crystallise trityl chloride from iso-octane. Also crystallise it from 5 parts of pet ether (b 90-100o) and 1 part of acetyl chloride using 1.8g of solvent per g of chloride. Dry it in a desiccator over soda lime and paraffin wax. [Bachman Org Synth Coll Vol III 841 1955, Thomas & Rochow J Am Chem Soc 79 1843 1957, Moisel et al. J Am Chem Soc 108 4706 1986, Beilstein 5 H 750, 5 I 346, 5 II 615, 5 III 2315, 5 IV 2497.] It is moisture sensitive and LACHRYMATORY,

Triphenylmethyl Chloride Preparation Products And Raw materials

Raw materials

TRIPHENYL METHANE CHLORID

Preparation Products

1-Trityl-1H-imidazole-4-carboxylic acid N-Boc-S-Trityl-L-cysteine 1H-Imidazole-4-carbaldehyde 2-(AMINOMETHYL)CYCLOPROPANECARBOXYLIC ACID
More
Less

Triphenylmethyl Chloride Suppliers

Americas 1 Austria 1 Belgium 1 Canada 5 China 636 China Hong Kong 1 Europe 7 France 1 Germany 13 India 67 Italy 1 Japan 13 Poland 1 Slovakia 1 South Korea 2 Switzerland 9 United Kingdom 13 United States 60 Global 833
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
Richman Chemical Inc
Tel
--
Fax
--
Email
clk@RichmanChemical.com
Country
United States
ProdList
238
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Advanced ChemTech (a division of CreoSalus Inc.)
Tel
--
Fax
--
Email
info@advancedchemtech.com
Country
United States
ProdList
177
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
AAPPTEC
Tel
--
Fax
--
Email
info@aapptec.com
Country
United States
ProdList
533
Advantage
0
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Morre-Tec Industries, Inc.
Tel
--
Fax
--
Email
sales@morretec.com
Country
United States
ProdList
169
Advantage
64
Fine Chemicals Inc.
Tel
--
Fax
--
Email
info@finechemicalsinc.com
Country
United States
ProdList
25
Advantage
50
SLN Pharmachem
Tel
--
Fax
--
Email
slnpharmachem@vsnl.net
Country
United States
ProdList
188
Advantage
43
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Magical Scientific LLC
Tel
--
Fax
--
Country
United States
ProdList
703
Advantage
0
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Global ChemSources, Inc.
Tel
--
Fax
--
Email
sales@globalchemsources.com
Country
United States
ProdList
132
Advantage
30
Parish Chemical Company
Tel
--
Fax
--
Country
United States
ProdList
1248
Advantage
47
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Aceto Corporation
Tel
--
Fax
--
Email
contact@aceto.com
Country
United States
ProdList
2619
Advantage
75
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
Empire Chemicals
Tel
--
Fax
--
Email
global@empirechemicals.com
Country
United States
ProdList
190
Advantage
38
Dishman Europe Ltd
Tel
--
Fax
--
Email
info@dishman-europe.com
Country
United States
ProdList
622
Advantage
58
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
More
Less

View Lastest Price from Triphenylmethyl Chloride manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Triphenylmethyl Chloride 76-83-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-28
Hebei Mojin Biotechnology Co.,Ltd
Product
Triphenylmethyl Chloride 76-83-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-07-19
Jinan Finer Chemical Co., Ltd
Product
Triphenylmethyl chloride 76-83-5
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
200mt
Release date
2021-12-13

76-83-5, Triphenylmethyl ChlorideRelated Search:

Polyvinyl chloride Ammonium chloride Choline chloride Chloromethane Triphenylmethane Sodium chloride Potassium chloride Diethylstilbestrol Chlorodiphenylmethane Acetyl chloride Calcium chloride Benzyl chloride Benzyltriphenylphosphonium chloride Triphenylsilyl chloride Triphenylsilane TRIS(DIMETHYLSILOXY)ETHOXYSILANE 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester OlMesartan MedoxoMil Methyl Ether IMpurity

  • [Chloro(diphenyl)methyl]benzene
  • 1,1’,1’’-(chloromethylidyne)tris-benzen
  • 1,1’,1’’(-Chloromethylidyne)trisben-zene
  • chlorotriphenyl-methan
  • Methane, chlorotriphenyl-
  • CHLOROTRIPHENYLMETHANE
  • BENZENE, 1,1',1''-(CHLOROMETHYLIDYNE)TRIS-
  • TRT-CL
  • TRITY CHLORIDE
  • TRITYL CHLORIDE
  • TRIPHENYLMETHYL CHLORIDE
  • TRIPHENYLCHLORMETHANE
  • TRIPHENYLCHLOROMETHANE
  • Triphenylmethyl chloride,98%
  • Triphenylmethyl chloride,99%
  • alpha-chlorotriphenylmethane
  • Triphenylchloromethane pure
  • Chlorotrisphenylmethane
  • TriphenylMethyl chloride, 98% 100GR
  • TriphenylMethyl chloride, 98% 500GR
  • NSC 435
  • CHLOROTRIPHENYLMETHANE FOR SYNTHESIS
  • Chlorotriphenylmethane, 1,1',1''-(Chloromethanetriyl)tribenzene
  • Trityl chloride puruM, >=97.0% (HPLC), >=97.0% (AT)
  • Trityl chloride, polymer-bound 100-200 mesh, extent of labeling: ~1.1 mmol/g Cl loading
  • (ChloroMethanetriyl)tribenzene
  • Trityl Chloride 〔Chlorotriphenylmethane〕
  • Triphenylmethyl chloride≥ 99% (HPLC)
  • Trt-Cl Chlorotriphenylmethane Triphenylchloromethane Triphenylmethyl chloride
  • Chlortriphenylmethan
  • PH3C-CL
  • D-(-)-p-Hydroxyphenylglycine Dane Salt(M.K.)
  • syn. Nae Chlorotriphenylmethane
  • Trityl chloride (Triphenylchloromethane)
  • Triphenylmethyl chloride (Trityl chloride)
  • TryTylchloride
  • Chlorotriphenylmethane,98%
  • Triphenyl chloeomethane
  • Triphenylchloromethan
  • TRITYL CHLORIDE 98%
  • TRT-CL(TRITYLCHLORIDE)
  • Triphenylmethyl chlorideChlorotriphenylmethane
  • Chlorotriphenylmethane, Triphenylchloromethane, Triphenylmethyl chloride
  • [Chloro-di(phenyl)methyl]benzen
  • Trityl chloride ,99%
  • Chloromethylidynetrisbenzene
  • Tritylchloride-Assay
  • Co-Formula CFS-835
  • CFS-835
  • TritylChloride&gt
  • Trityl chloride, 99%, for synthesis
  • Triphenylmethyl chloride,97%
  • TriphenylMethyl chloride USP/EP/BP
  • Boscalid 188425-85-6
  • Trityl Chloride [TTC
  • Triphenylmet
  • Ttityl Chloride
  • TRITYL CHLORIDE(TTCL)