BIG ENDOTHELIN-1 (1-39) (RAT)

Product Name: BIG ENDOTHELIN-1 (1-39) (RAT)
CAS No.: 135842-15-8
Chemical Name: BIG ENDOTHELIN-1 (1-39) (RAT)
Synonyms: BIG ET-1 (1-39) (RAT);BIG ENDOTHELIN 39 RAT;BIG ENDOTHELIN-1 (RAT, 1-39);BIG ENDOTHELIN-1 (1-39) (RAT);CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER;H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER-OH;CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER: CSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGSPSRSDISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
CBNumber: CB8671013
Molecular Formula: C192H292N50O58S5
Formula Weight: 4389
MOL File: Mol file

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BIG ENDOTHELIN-1 (1-39) (RAT) Property

storage temp.: −20°C
form: Solid

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E7265
Product name: Big Endothelin 39 rat
Purity: ≥97% (HPLC)
Packaging: 0.1mg
Price: $742
Updated: 2024/03/01

Alfa Aesar

Product number: J66662
Product name: Big Endothelin-1 (1-39), rat
Packaging: 0.5mg
Price: $372
Updated: 2021/12/16

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BIG ENDOTHELIN-1 (1-39) (RAT) Chemical Properties,Usage,Production

Description

Big endothelin-1(1-39) (RAT) is a 39 amino acid peptide, which is synthesized and secreted by vascular smooth muscle and endothelium cells. It is produced as an inactive enzyme, and is cleaved and activated by serine and aspartic proteases and metalloproteinases. Activated form is called ET-1, which is a potent vasoconstrictor. ET-1 is also produced by the action of endothelin converting enzyme (ECE) on big-ET-1. In guinea pigs, big-ET-1 causes the release of prostanoids and thromboxanes.

Uses

Big endothelin-1(1-39) (RAT) has been used for charting of a standard curve in the study of the role of ET-1 in ventricular dilatation.

Biological Activity

Precursor of Endothelin-1; vasoconstrictor activity appears to be due to its conversion to endothelin 1 by endothelin converting enzyme in the tissue.

BIG ENDOTHELIN-1 (1-39) (RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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BIG ENDOTHELIN-1 (1-39) (RAT) Suppliers

China 12 Japan 1 Switzerland 3 United States 3 Global 19

GL Biochem (Shanghai) Ltd

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Nanjing Leon Biological Technology Co., Ltd.

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Nanjing Peptide Biotech Ltd.

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Hangzhou Peptidego Biotech Co.,Ltd.

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Wuxi Helen Biotechnology Co., Ltd.,

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TCI (Shanghai) Chemical Trading Co., Ltd.

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Hangzhou Sinoda Pharmaceutical Technology Co. LTD

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Shanghai Toyang Biotechnology Co., LTD

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135842-15-8, BIG ENDOTHELIN-1 (1-39) (RAT)Related Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Cupric acetylacetonate METHYL ISOCYANOACETATE Tris(2,4-pentanedionato)chroMiuM(III) Aluminum acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) 2,4-PENTANEDIONE, SILVER DERIVATIVE PHENYLSELENOL TERT-BUTYL ISOCYANIDE Ferric acetylacetonate Ethyl isocyanoacetate COBALT(II) ACETYLACETONATE Benzyl isocyanide N-BUTYLISOCYANIDE

CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER: CSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGSPSRSDISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11

H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER-OH

CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER

BIG ENDOTHELIN-1 (1-39) (RAT)

BIG ENDOTHELIN-1 (RAT, 1-39)

BIG ENDOTHELIN 39 RAT

BIG ET-1 (1-39) (RAT)

135842-15-8

C192H292N50O58S5

BioChemical

Amino Acids and Peptides

Biochemicals and Reagents

Precursors

Peptides

Endothelins

Peptides for Cell Biology

Precursors