ChemicalBook > CAS DataBase List > BIG ENDOTHELIN-1 (1-39) (RAT)
BIG ENDOTHELIN-1 (1-39) (RAT)
- Product Name
- BIG ENDOTHELIN-1 (1-39) (RAT)
- CAS No.
- 135842-15-8
- Chemical Name
- BIG ENDOTHELIN-1 (1-39) (RAT)
- Synonyms
- BIG ET-1 (1-39) (RAT);BIG ENDOTHELIN 39 RAT;BIG ENDOTHELIN-1 (RAT, 1-39);BIG ENDOTHELIN-1 (1-39) (RAT);CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER;H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER-OH;CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER: CSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGSPSRSDISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
- CBNumber
- CB8671013
- Molecular Formula
- C192H292N50O58S5
- Formula Weight
- 4389
- MOL File
- Mol file
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BIG ENDOTHELIN-1 (1-39) (RAT) Property
- storage temp.
- −20°C
- form
- Solid
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E7265
- Product name
- Big Endothelin 39 rat
- Purity
- ≥97% (HPLC)
- Packaging
- 0.1mg
- Price
- $574
- Updated
- 2025/07/31
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BIG ENDOTHELIN-1 (1-39) (RAT) Chemical Properties,Usage,Production
Description
Big endothelin-1(1-39) (RAT) is a 39 amino acid peptide, which is synthesized and secreted by vascular smooth muscle and endothelium cells. It is produced as an inactive enzyme, and is cleaved and activated by serine and aspartic proteases and metalloproteinases. Activated form is called ET-1, which is a potent vasoconstrictor. ET-1 is also produced by the action of endothelin converting enzyme (ECE) on big-ET-1. In guinea pigs, big-ET-1 causes the release of prostanoids and thromboxanes.
Uses
Big endothelin-1(1-39) (RAT) has been used for charting of a standard curve in the study of the role of ET-1 in ventricular dilatation.
Biological Activity
Precursor of Endothelin-1; vasoconstrictor activity appears to be due to its conversion to endothelin 1 by endothelin converting enzyme in the tissue.
BIG ENDOTHELIN-1 (1-39) (RAT) Preparation Products And Raw materials
Raw materials
Preparation Products
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BIG ENDOTHELIN-1 (1-39) (RAT) Suppliers
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