Ethyl thiophene-3-carboxylate
- Product Name
- Ethyl thiophene-3-carboxylate
- CAS No.
- 5751-80-4
- Chemical Name
- Ethyl thiophene-3-carboxylate
- Synonyms
- THOO2;3-thenoate;ethyl 3-thenoate;RARECHEM AL BI 0549;ETHYL 3-THIENYLACETATE;ETHYL 3-THIOPHENEACETATE;ETHYL THIOPHENE-3-ACETATE;Thiophene -3-ethyl forMate;Ethyl thiophen-3-carboxylate;ETHYL THIOPHENE-3-CARBOXYLATE
- CBNumber
- CB8737087
- Molecular Formula
- C7H8O2S
- Formula Weight
- 156.2
- MOL File
- 5751-80-4.mol
Ethyl thiophene-3-carboxylate Property
- Boiling point:
- 97-98 °C (8 mmHg)
- Density
- 1.12
- refractive index
- 1.509-1.511
- Flash point:
- 103 °C
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- Water Solubility
- Soluble in water.
Safety
- Safety Statements
- 24/25-23
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E1082
- Product name
- Ethyl 3-Thiophenecarboxylate
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- E1082
- Product name
- Ethyl 3-Thiophenecarboxylate
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $121
- Updated
- 2025/07/31
- Product number
- E818128
- Product name
- EthylThiophene-3-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- E818128
- Product name
- EthylThiophene-3-carboxylate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- JK172772
- Product name
- Ethylthiophene-3-carboxylate
- Purity
- 98%
- Packaging
- 25g
- Price
- $490
- Updated
- 2021/12/16
Ethyl thiophene-3-carboxylate Chemical Properties,Usage,Production
Chemical Properties
Colorless liquid
Uses
Ethyl thiophene-3-carboxylate is used as an intermediate in organic syntheses
Synthesis
64-17-5
88-13-1
5751-80-4
Thirteen mL (200 mmol) of thionyl chloride was added slowly and dropwise at 0 °C to a 100 mL ethanol solution containing 9 g (70 mmol) of 3-thiophenecarboxylic acid and 86 mg (0.7 mmol) of 4-dimethylaminopyridine. The reaction mixture was gradually warmed from 0 °C to room temperature over 48 h with continuous stirring. Subsequently, the reaction solution was evaporated to dryness. The resulting residue was purified by silica column chromatography with the eluent being a 1:1 heptane/dichloromethane solvent mixture. Finally 10 g (91% yield) of ethyl thiophene-3-carboxylate was obtained.
References
[1] Patent: WO2004/113331, 2004, A1. Location in patent: Page 38-39
[2] Organic Process Research and Development, 2017, vol. 21, # 7, p. 947 - 955
[3] Organic Letters, 2008, vol. 10, # 9, p. 1851 - 1854
[4] Angewandte Chemie - International Edition, 2017, vol. 56, # 33, p. 9924 - 9929
[5] Angew. Chem., 2017, vol. 129, p. 10056 - 10061,6
Ethyl thiophene-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl thiophene-3-carboxylate Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from Ethyl thiophene-3-carboxylate manufacturers
- Product
- Ethyl thiophene-3-carboxylate 5751-80-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97-99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-18