4'-Hydroxy-3'-nitroacetophenone
- Product Name
- 4'-Hydroxy-3'-nitroacetophenone
- CAS No.
- 6322-56-1
- Chemical Name
- 4'-Hydroxy-3'-nitroacetophenone
- Synonyms
- 1-(4-hydroxy-3-nitrophenyl)ethan-1-one;NSC 32113;2-Nitro-4-acetylphenol;Formoterol Impurity 68;4-ACETYL-2-NITRO-PHENOL;Acetophenone Impurity 8;-Hydroxy-3-nitroacetophenone;4-HYDROXY-3-NITROACETOPHENONE;3-NITRO-4-HYDROXY ACETOPHENONE;3'-NITRO-4'-HYDROXYACETOPHENONE
- CBNumber
- CB9114043
- Molecular Formula
- C8H7NO4
- Formula Weight
- 181.15
- MOL File
- 6322-56-1.mol
4'-Hydroxy-3'-nitroacetophenone Property
- Melting point:
- 132-135 °C(lit.)
- Boiling point:
- 314.24°C (rough estimate)
- Density
- 1.4283 (rough estimate)
- refractive index
- 1.5468 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate
- form
- powder to crystal
- pka
- 5.18±0.14(Predicted)
- color
- Light yellow to Amber to Dark green
- BRN
- 1959078
- CAS DataBase Reference
- 6322-56-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Hydroxy-3-nitroacetophenone(6322-56-1)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29147000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 330256
- Product name
- 4′-Hydroxy-3′-nitroacetophenone
- Purity
- 98%
- Packaging
- 1g
- Price
- $42.9
- Updated
- 2023/01/07
- Product number
- H0968
- Product name
- 4'-Hydroxy-3'-nitroacetophenone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- H948610
- Product name
- 4’-Hydroxy-3’-nitroacetophenone,>95%
- Packaging
- 2g
- Price
- $800
- Updated
- 2021/12/16
- Product number
- H948610
- Product name
- 4’-Hydroxy-3’-nitroacetophenone,>95%
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- JK117789
- Product name
- 4'-Hydroxy-3'-nitroacetophenone
- Purity
- 98%
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
4'-Hydroxy-3'-nitroacetophenone Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
4’-Hydroxy-3’-nitroacetophenone, >95% (cas# 6322-56-1) is a compound useful in organic synthesis.
Uses
4′-Hydroxy-3′-nitroacetophenone may be used in chemical synthesis.
Preparation
Preparation by nitration of 4-hydroxyacetophenone.
Synthesis
99-93-4
6322-56-1
The general procedure for the synthesis of 4'-hydroxy-3'-nitroacetophenone from p-hydroxyacetophenone was as follows: phenol (94 mg, 1 mmol) was dissolved in 3 mL of glacial acetic acid in a 50 mL test tube. Solid Y(NO3)3-6H2O (383 mg, 1 mmol) was then added and the reaction mixture was shaken continuously for 10 min at room temperature. The reaction process was monitored by thin layer chromatography (TLC) in petroleum ether with 10% ethyl acetate. After completion of the reaction, 30 mL of ice-cold water was added to the reaction mixture and allowed to stand for 15 min. The solid product was collected by filtration and washed with distilled water. The resulting solid product was used for analysis without further purification. The experimental methods for synthesizing compounds 2a-2e are detailed in Supporting Information.
References
[1] Synthetic Communications, 1997, vol. 27, # 19, p. 3301 - 3311
[2] Synlett, 2003, # 2, p. 191 - 194
[3] Synthetic Communications, 2008, vol. 38, # 19, p. 3366 - 3374
[4] Chinese Chemical Letters, 2011, vol. 22, # 7, p. 827 - 830
[5] Synthetic Communications, 1998, vol. 28, # 15, p. 2773 - 2781
4'-Hydroxy-3'-nitroacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4'-Hydroxy-3'-nitroacetophenone manufacturers
- Product
- 4'-Hydroxy-3'-nitroacetophenone 6322-56-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28
- Product
- 4'-Hydroxy-3'-nitroacetophenone 6322-56-1
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 4'-Hydroxy-3'-nitroacetophenone 6322-56-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10