Alarelin Acetate
- Product Name
- Alarelin Acetate
- CAS No.
- 79561-22-1
- Chemical Name
- Alarelin Acetate
- Synonyms
- Alarelin Acetate;(DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR (SEA BREAM);ALARELIN;SURFAGON;Allah Lin;Alareline Acetate;Alarelin impurity;Alarelin USP/EP/BP;Alarelin DiAcetate;Alarelin acetate salt
- CBNumber
- CB9119598
- Molecular Formula
- C58H82N16O14
- Formula Weight
- 1227.39
- MOL File
- 79561-22-1.mol
Alarelin Acetate Property
- storage temp.
- −20°C
- solubility
- ≥128.7 mg/mL in DMSO; ≥128.6 mg/mL in EtOH; ≥128.8 mg/mL in H2O
- form
- powder
- Sequence
- Glu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
- InChIKey
- IMRONVSKLHSCMF-VWCBMNBRNA-N
N-Bromosuccinimide Price
- Product number
- BA164142
- Product name
- Alarelin Acetate
- Packaging
- 10mg
- Price
- $97
- Updated
- 2021/12/16
- Product number
- CS-1172
- Product name
- Alarelin(Acetate)
- Purity
- 99.43%
- Packaging
- 10mg
- Price
- $108
- Updated
- 2021/12/16
- Product number
- A3151
- Product name
- AlarelinAcetate
- Packaging
- 50mg
- Price
- $137
- Updated
- 2021/12/16
- Product number
- BA164142
- Product name
- Alarelin Acetate
- Packaging
- 50mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FA64933
- Product name
- Alarelin Acetate
- Packaging
- 100mg
- Price
- $150
- Updated
- 2021/12/16
Alarelin Acetate Chemical Properties,Usage,Production
Biological Activity
alarelin (gonadotrophin-releasing hormone) is a synthetic gnrh agonist. alarelin is found in higher amounts than that of lh-rh in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. alarelin is known for its induction of ovulation and is used to treat endmometriosis. alarelin acetate is the acetate form of a hypothalamic peptide that stimulates the release of fsh and lh from the pituitary gland.
Cytotoxicity
Cell Assay
The cells are trypsinized in a solution of 2.5 g/L trypsin and seeded in a 96-well plate. After the cells are grown for 24 h to approximately 800 g/L subconfluent state, 0.1 mL medium containing 2.5% calf serum and various concentrations (0.001, 0.1, 10 μM) of alarelin is added to each well, respectively, and incubated for 24 h in a CO2 incubator. Each concentration is tested in at least 12 wells. Briefly, 15 μL of MTT solution is added to each well and incubated for 4 h. Then, the medium and MTT are removed and 150 μL of DMSO is added to each well and shaken for 10 min to dissolve the crystal. The OD is determined at 490 nm using an ELISA reader.
Animal Administration
Rats: Male Sprague-Dawley rats are divided into two groups. In Group I: Gastric acid secretion is measured in a chambered stomach. Briefly, the abdomen is incised, and both the stomach and duodemun are exposed and tied respectively; then 1.5 mL 0.9% sodium chloride (containing Alarelin, 2 μg/kg) is infused into the each chambered stomach. After 15, 30, 45, 60 min, the gastric juice is drew out of the chambered stomach and the pH is measured in the ABL-500 respectively. The control is infused saline instead of Alarelin. In Group II: After anaesthetized, 2 mL Alarelin (2 μg/kg) is administered into the tail vein. The control is injected the saline instead of Alarelin. Then, the stomach and duodenum are tied and infused 1.5 mL saline immediately. After 15, 30, 45, 60 min, the gastric juice is also drew out of the chambered stomach and the pH is measured in the ABL-500 respectively.
Alarelin Acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Alarelin Acetate Suppliers
View Lastest Price from Alarelin Acetate manufacturers
- Product
- Alarelin 79561-22-1
- Price
- US $30.00/box
- Min. Order
- 1box
- Purity
- 98%
- Supply Ability
- 5000 box
- Release date
- 2024-03-20
- Product
- Alarelin Acetate 79561-22-1
- Price
- US $26.00-22.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 100000box
- Release date
- 2024-05-17
- Product
- Alarelin Acetate 79561-22-1
- Price
- US $75.00-750.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-01