ChemicalBook > CAS DataBase List > 5-BROMO-2-METHOXY-3-CYANOPYRIDINE

5-BROMO-2-METHOXY-3-CYANOPYRIDINE

Product Name
5-BROMO-2-METHOXY-3-CYANOPYRIDINE
CAS No.
884495-39-0
Chemical Name
5-BROMO-2-METHOXY-3-CYANOPYRIDINE
Synonyms
5-BroMo-2-Methoxy-3-aMino...;5-Bromo-2-methoxypyridin-3-amine;5-bromo-6-methoxypyridin-4-amine;3-PyridinaMine,5-broMo-2-Methoxy-;5-BROMO-2-METHOXY-3-AMINOPYRIDINE;5-BROMO-2-METHOXY-3-CYANOPYRIDINE;2-methoxy-3-amino-5-bromopyridine;5-BroMo-2-(Methyloxy)-3-pyridinaMine;3-Amino-5-bromo-2-methoxypyridine,96%;3-Amino-5-bromo-2-methoxypyridine 98%
CBNumber
CB91471022
Molecular Formula
C6H7BrN2O
Formula Weight
203.04
MOL File
884495-39-0.mol
More
Less

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Property

Melting point:
53-55℃
Boiling point:
284.5±35.0 °C(Predicted)
Density 
1.622±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
1.98±0.20(Predicted)
Appearance
Off-white to light brown Solid
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C6H7BrN2O/c1-10-6-5(8)2-4(7)3-9-6/h2-3H,8H2,1H3
InChIKey
HJOOFLFWIISCAI-UHFFFAOYSA-N
SMILES
C1(OC)=NC=C(Br)C=C1N
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41-43
Safety Statements 
26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000451
Product name
5-Bromo-2-methoxypyridin-3-amine
Purity
Aldrich
Packaging
1g
Price
$463
Updated
2023/06/20
TRC
Product number
B699685
Product name
5-Bromo-2-methoxypyridin-3-amine
Packaging
50mg
Price
$60
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
Y14224
Product name
3-Amino-5-bromo-2-methoxypyridine
Purity
98%
Packaging
1g
Price
$5
Updated
2021/12/16
Matrix Scientific
Product number
048666
Product name
5-Bromo-2-methoxy-3-pyridinamine
Purity
95+%
Packaging
1g
Price
$10
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
Y14224
Product name
3-Amino-5-bromo-2-methoxypyridine
Purity
98%
Packaging
5g
Price
$15
Updated
2021/12/16
More
Less

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Chemical Properties,Usage,Production

Uses

3-Amino-5-bromo-2-methoxypyridine is used as pharmaceutical intermediate.

Synthesis

152684-30-5

884495-39-0

General procedure for the synthesis of 3-amino-5-bromo-2-methoxypyridine from 5-bromo-2-methoxy-3-nitropyridine: To a solution of 5-bromo-2-methoxy-3-nitropyridine (19.0 g, 82 mmol) in ethyl acetate (300 mL) was added tin (II) chloride dihydrate (74 g, 328 mmol). The reaction mixture was stirred and refluxed for 3 hours (note: an exothermic phenomenon occurs at the beginning of the reaction, which gradually subsides after about 10 minutes, at which time the heating bath can be temporarily removed). After completion of the reaction, the reaction mixture was cooled to room temperature and concentrated under reduced pressure to a light yellow slurry. The slurry was poured into water (300 mL), 6 N sodium hydroxide solution (300 mL), ice (300 g), and dichloromethane (300 mL) were added, and stirred for 2 hours until most of the solids were dissolved. A small amount of insoluble material was removed by filtration, the organic phase was separated, dried over anhydrous sodium sulfate, filtered and evaporated to dryness. The residual brown oil was solidified by grinding with hexane, filtered and dried under vacuum to give the target product 3-amino-5-bromo-2-methoxypyridine (13.40 g, 81% yield) as a light green solid. Mass spectrum (electrospray ionization) m/e: 202.8 [M+H]+.

References

[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0387
[2] Patent: WO2008/33854, 2008, A1. Location in patent: Page/Page column 74-75
[3] Patent: WO2014/22128, 2014, A1. Location in patent: Paragraph 0150
[4] Patent: US2014/234254, 2014, A1. Location in patent: Paragraph 0300; 0301; 0302
[5] Patent: CN103539777, 2016, B. Location in patent: Paragraph 0304; 0305

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-BROMO-2-METHOXY-3-CYANOPYRIDINE Suppliers

China 187 Germany 1 India 9 United Kingdom 2 United States 14 Global 213
Changzhou chennuo Biotechnology Co., Ltd
Tel
17768395970
Email
35015765@qq.com
Country
China
ProdList
45
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
ChangShu Haitian Fine Chemicals Co.,Ltd
Tel
13913622609
Fax
86-512-52893680
Email
974295387@qq.com
Country
China
ProdList
192
Advantage
61
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2806
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Shanghai Waytry Pharmas Co. Ltd.
Tel
021-50728690 18101878792
Fax
+86-21-50728690
Email
sales@waytrypharms.com
Country
China
ProdList
49
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
3991
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
354
Advantage
60
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Halogen Technology（xinzhou).Co., Ltd
Tel
86-0350 3026661 13935073081
Fax
86 0350 3026661
Country
China
ProdList
35
Advantage
55
Hebei Summedchem Co.,Ltd
Tel
0319-5801333-8008 15630992918
Email
sales@summedchem.com
Country
China
ProdList
965
Advantage
58
Jinan Mingya Medical Technology Co., Ltd.
Tel
0531-85828981
Fax
+86-531-85806006
Email
864598798@qq.com
Country
China
ProdList
588
Advantage
58
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2647
Advantage
55
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
488
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4641
Advantage
60
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Nanjing Duolong Bio-tech Co.,Ltd.
Tel
18905173768
Fax
025-83263139
Email
52513593@qq.com
Country
China
ProdList
2331
Advantage
50
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3280
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4161
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536 13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3282
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4193
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4610
Advantage
58
Beijing HuaYangZhicheng Technology Co., Ltd.
Tel
13716033033
Fax
010-56276266
Email
hanchochem@163.com
Country
China
ProdList
2960
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Shanghai LanRun Chemical Co., Ltd.
Tel
021-69515658 ; 69515628 13701998368
Fax
021-69515998
Email
longrunchem@163.com
Country
China
ProdList
3786
Advantage
50
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4613
Advantage
50
More
Less

View Lastest Price from 5-BROMO-2-METHOXY-3-CYANOPYRIDINE manufacturers

Dideu Industries Group Limited
Product
5-BROMO-2-METHOXY-3-CYANOPYRIDINE 884495-39-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Shaanxi Dideu Medichem Co. Ltd
Product
5-Bromo-2-methoxypyridin-3-amine 884495-39-0
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12
Career Henan Chemical Co
Product
5-BROMO-2-METHOXY-3-CYANOPYRIDINE 884495-39-0
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-19

884495-39-0, 5-BROMO-2-METHOXY-3-CYANOPYRIDINERelated Search:

3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE 3-Pyridinamine, 5-chloro-2-methoxy- 5-AMINO-3-BROMO-2-METHYLPYRIDINE 5-Chloro-2-methyl-3-nitropyridine 3-Bromo-2-methoxy-5-nitropyridine 5-AMINO-3-BROMO-2-METHOXYPYRIDINE 5-BROMO-2-METHOXY-4-METHYLPYRIDINE 5-BROMO-2-METHOXY-3-NITRO-PYRIDINE 3-BROMO-2-METHOXY-6-PICOLINE 3-BROMO-5-FLUORO-2-METHOXYPYRIDINE 2-Methoxy-3-nitropyridine 5-AMINO-2-METHOXY-3-METHYLPYRIDINE HCL 2-Methoxy-3-fluoro-5-bromopyridine 6-Chloro-2-methoxy-3-nitropyridine 2-METHOXY-3,5-DIBROMO-PYRIDINE 2-Methoxy-5-nitro-3-picoline 2-Methoxy-3-(trifluoromethyl)pyridine 3-Iodo-2-methoxypyridine

  • 5-BROMO-2-METHOXY-3-CYANOPYRIDINE
  • 5-BROMO-2-METHOXY-3-AMINOPYRIDINE
  • 5-BroMo-2-Methoxy-3-aMino...
  • 5-Bromo-2-methoxypyridin-3-amine
  • 3-PyridinaMine,5-broMo-2-Methoxy-
  • 5-BroMo-2-(Methyloxy)-3-pyridinaMine
  • 5-Bromo-2-methoxypyridin-3-amine, 3-Amino-5-bromopyridin-2-yl methyl ether
  • 3-Amino-5-bromopyridin-2-yl methyl ether
  • 2-methoxy-3-amino-5-bromopyridine
  • 3-Amino-5-bromo-2-methoxypyridine 98%
  • 3-Amino-5-bromo-2-methoxypyridine,96%
  • 5-bromo-6-methoxypyridin-4-amine
  • 5-BROMO-2-METHOXY-3-CYANOPYRIDINE ISO 9001：2015 REACH
  • 884495-39-0
  • Heterocycle-Pyridine series
  • Pyridine