ChemicalBook > CAS DataBase List > 4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER

4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER

Product Name
4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER
CAS No.
185312-82-7
Chemical Name
4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER
Synonyms
Methyl 4-bromo-2-chlorobenzoate;BENZOIC ACID,4-BROMO-2-CHLORO-,METHYL ESTER;Methyl 4-bromo-2-chlorobenzoate 98%;4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER
CBNumber
CB91485023
Molecular Formula
C8H6BrClO2
Formula Weight
249.49
MOL File
185312-82-7.mol
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4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER Property

Boiling point:
295.1±20.0 °C(Predicted)
Density 
1.604±0.06 g/cm3(Predicted)
refractive index 
1.5770 to 1.5810
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow to Light orange
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2883
Product name
Methyl 4-Bromo-2-chlorobenzoate
Purity
>98.0%(GC)
Packaging
1g
Price
$45
Updated
2025/07/31
TCI Chemical
Product number
M2883
Product name
Methyl 4-Bromo-2-chlorobenzoate
Purity
>98.0%(GC)
Packaging
5g
Price
$150
Updated
2025/07/31
TRC
Product number
M296540
Product name
Methyl 4-Bromo-2-chlorobenzoate
Packaging
50mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
119884
Product name
Methyl 4-bromo-2-chlorobenzoate
Purity
95+%
Packaging
10g
Price
$892
Updated
2021/12/16
AK Scientific
Product number
Z1776
Product name
Methyl 4-Bromo-2-chlorobenzoate
Packaging
100g
Price
$1011
Updated
2021/12/16
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4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

59748-90-2

185312-82-7

A. Methyl esterification: Dry hydrogen chloride gas was passed into a 100 ml methanol solution containing 10 g (42.5 mmol) of 4-bromo-2-chlorobenzoic acid until the solution began to reflux. The reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming that the reaction was essentially complete, the reaction mixture was concentrated under reduced pressure to give the crude product. The crude product was redissolved in ether and washed sequentially with deionized water (twice) and saturated sodium chloride solution. The organic phase was dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to afford 10 g of the light tan oily target product methyl 2-chloro-4-bromobenzoate in 94% yield.

References

[1] Patent: US5786325, 1998, A
[2] Patent: US6511974, 2003, B1
[3] Patent: US5932745, 1999, A
[4] Patent: US6831079, 2004, B1. Location in patent: Page/Page column 55

4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-2-CHLOROBENZOIC ACID METHYL ESTER Suppliers

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