5-Hydroxyindole

Product Name: 5-Hydroxyindole
CAS No.: 1953-54-4
Chemical Name: 5-Hydroxyindole
Synonyms: 1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
CBNumber: CB9151600
Molecular Formula: C8H7NO
Formula Weight: 133.15
MOL File: 1953-54-4.mol

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5-Hydroxyindole Property

Melting point:: 106-108 °C(lit.)
Boiling point:: 245.66°C (rough estimate)
Density: 1.1475 (rough estimate)
refractive index: 1.5260 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: 38g/l
form: Crystalline Needles or Powder
pka: 9.98±0.40(Predicted)
color: beige
Sensitive: Light Sensitive
BRN: 112349
CAS DataBase Reference: 1953-54-4(CAS DataBase Reference)
NIST Chemistry Reference: Indol-5-ol(1953-54-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: NM2430000
HazardClass: IRRITANT, KEEP COLD
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H31859
Product name: 5-Hydroxyindole
Purity: 97%
Packaging: 1g
Price: $68.5
Updated: 2024/03/01

TCI Chemical

Product number: H0252
Product name: 5-Hydroxyindole
Purity: >98.0%(GC)
Packaging: 100mg
Price: $18
Updated: 2024/03/01

TCI Chemical

Product number: H0252
Product name: 5-Hydroxyindole
Purity: >98.0%(GC)
Packaging: 1g
Price: $57
Updated: 2024/03/01

Alfa Aesar

Product number: L00858
Product name: 5-Hydroxyindole, 98+%
Packaging: 1g
Price: $50.65
Updated: 2024/03/01

Alfa Aesar

Product number: L00858
Product name: 5-Hydroxyindole, 98+%
Packaging: 5g
Price: $185.65
Updated: 2024/03/01

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5-Hydroxyindole Chemical Properties,Usage,Production

Chemical Properties

beige to brown crystalline needles or powder

Uses

• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6

Uses

5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.

Definition

ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017

5-Hydroxyindole Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitrophenol potassium ferricyanide Palladium Benzyl bromide N,N-Dimethylformamide dimethyl acetal

Preparation Products

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5-Hydroxyindole Suppliers

Americas 1 Belgium 1 Canada 1 China 293 Europe 3 Germany 5 India 22 Japan 4 Slovakia 1 Switzerland 6 Ukraine 1 United Kingdom 18 United States 75 Global 431

Molekula Limited

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Manchester Organics

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Apollo Scientific Ltd.

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Apin Chemicals Limited (UK)

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Leancare Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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ARIAC - Armenian Institute of Applied Chemistry

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MOLEKULA Ltd.

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ETA SCIENTIFIC Co.,Ltd

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UK GREEN SCIENTIFIC CO.,LIMITED

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Fluorochem Ltd

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Fluorochem Ltd.

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Apin Chemicals Ltd.

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VWR International

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MDA Chemicals Ltd.

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Fulcrum Scientific Ltd.

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Eurolabs Limited

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View Lastest Price from 5-Hydroxyindole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 5-Hydroxyindole 1953-54-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-22

Hebei Weibang Biotechnology Co., Ltd

Product: 5-Hydroxyindole 1953-54-4
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Hebei Chuanghai Biotechnology Co,.LTD

Product: 5-Hydroxyindole 1953-54-4
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 1 ton
Release date: 2024-08-21

1953-54-4, 5-HydroxyindoleRelated Search:

Indole-3-acetic acid Indole-3-butyric acid Chrysin Indometacin 5-HYDROXYOXINDOLE 2,3-DIHYDROINDOL-5-OL 5-Methoxyindole-3-carboxaldehyde 5,6-Dimethoxyindole 5-Methoxyindole 5-METHOXY-2-METHYLINDOLE 5-BENZYLOXYGRAMINE Melatonine DL-5-HYDROXYTRYPTOPHAN 5-Benzyloxyindole 5-Methoxytryptamine 7-HYDROXYINDOLE 5-METHOXY-DL-TRYPTOPHAN 4-HYDROXYINDOLE

5-Hydroxy-1H-indole

Hydroxy-5 indole

hydroxy-5indole

TIMTEC-BB SBB004214

1H-INDOL-5-OL

5-HYDROXYINDOLE

5-INDOLOL

INDOL-5-OL

Hydroxyindole,98%

5-hdroxyindole

5-HYDROXYINDOLE 99%

5-Hydroxyindole, 98+%

5-HYDROXYINDOLE (5OHI)

5-Hydroxyindole,97%

5-Hydroxyindole,5-Hydroxyindole, 5-Indolol

5-Hydroxyindole, 97% 1GR

5-carboxylindoline 2,3-dihydro-1h-indole-5-carboxylic Acid Indoline-5-carboxylic acid in stock Factory

5-Hydroxy-1H-indole 98%

NSC 87503

5-Hydroxyindoline

5-Hydroxyindole&gt

5-Hydroxyindole ISO 9001：2015 REACH

5-Hydroxyindole?New

5-Hydroxyindole, ≥ 98.0%

1953-54-4

1593-54-4

1953-94-4

Building Blocks

Indoles

Simple Indoles

Heterocyclic Building Blocks

Heterocycle-Indole series

Building Blocks

C7 to C9

Chemical Synthesis

Heterocyclic Building Blocks

Indoles

Simple Indoles

pharmacetical

Indole

indole derivative

Indoles and derivatives

blocks

IndolesOxindoles