1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

ChemicalBook > CAS DataBase List > 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

Uses

Product Name: 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
CAS No.: 446292-08-6
Chemical Name: 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
Synonyms: (S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione;Rivaroxaban-5;C22HjgNzO6;Rivaroxaban G;Rivaroxaban ImpVI;2-Amino-13-picoline;Rivaroxaban Intermediate5;Rivaroxaban EP Impurity G;Rivaroxaban Impurities365;RivaroxabanInterMediates-01
CBNumber: CB92468058
Molecular Formula: C22H19N3O6
Formula Weight: 421.4
MOL File: 446292-08-6.mol

Less

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Property

Melting point:: 213-215°C
Boiling point:: 702.9±55.0 °C(Predicted)
Density: 1.465±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 0.99±0.20(Predicted)
form: Solid
color: White to Off-White
Water Solubility: 12mg/L at 20℃
LogP: -0.2 at 25℃

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: P385850
Product name: 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
Packaging: 25mg
Price: $120
Updated: 2021/12/16

TRC

Product number: P385850
Product name: 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
Packaging: 50mg
Price: $155
Updated: 2021/12/16

TRC

Product number: P385850
Product name: 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
Packaging: 100mg
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: Z6156
Product name: 1H-Isoindole-1,3(2H)-dione,2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
Packaging: 25g
Price: $901
Updated: 2021/12/16

Matrix Scientific

Product number: 092112
Product name: (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)isoindoline-1,3-dione
Purity: 95+%
Packaging: 1g
Price: $975
Updated: 2021/12/16

Less

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Chemical Properties,Usage,Production

Uses

1H-isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- is an important intermediate for the synthesis of rivaroxaban, which is an anticoagulant and the first orally active direct factor Xa inhibitor.

Chemical Properties

White Solid

Uses

Rivaroxaban intermediate.

Flammability and Explosibility

Non flammable

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Suppliers

Canada 1 China 274 India 21 United Kingdom 1 United States 9 Global 306

Suzhou lipin Chemical Co., Ltd

Tel: 0512-0512-67509664 19888480046
Country: China
ProdList: 121
Advantage: 58

Harway Pharma CO., LTD

Tel: 0546-5612566 13793982289
Fax: 0546-5180666
Email: lucy@harwaypharma.com
Country: China
ProdList: 41
Advantage: 58

Jiangxi taisinor Co., Ltd.

Tel: 13576915071
Email: taisinor@vip.163.com
Country: China
ProdList: 7
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2882
Advantage: 65

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Anhui Lianchuang Biological Medicine Co.,Ltd

Tel: 0551-68779238 18056025720
Email: sales3@lcywhx.com
Country: China
ProdList: 168
Advantage: 57

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4550
Advantage: 62

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4979
Advantage: 50

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9901
Advantage: 58

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4673
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Acesys Pharmatech

Tel: 18860950986
Email: tangmanman@zenjipharma.com
Country: China
ProdList: 1735
Advantage: 55

Bsisun HK Imoprt And Export Company Limited

Tel: +86-18068513926
Fax: 0086-519-85153711
Country: China
ProdList: 1280
Advantage: 55

Hunan Furui Biopharma Technology Co., Ltd.

Tel: 15902102743
Fax: 0731-57805668
Email: shelley@furuipharma.com
Country: China
ProdList: 425
Advantage: 55

Shanghai Twisun Bio-pharm Co.,Ltd

Tel: +86-21-33282107
Fax: +86-21-37285115
Country: China
ProdList: 107
Advantage: 60

Beijin Yangguang Furui Chemical co.,Ltd.

Tel: 010-57495520 13521095525
Email: zhw512@foxmail.com
Country: China
ProdList: 490
Advantage: 55

Changzhou EFC Chemistry&Science Co.,Ltd

Tel: 18136598690 18136597130
Fax: 86-0519-89617886
Country: China
ProdList: 235
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

ChemStrong Scientific Co.,Ltd

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Hefei TianRui Pharmaceutical Chemistry Co., Ltd.

Tel: 0551-68933033 13956024211
Fax: 0551-68935833
Email: trchem@163.com
Country: China
ProdList: 90
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Shanghai SE Pharm Co., Ltd

Tel: 18112588827
Email: sales4@sepharm.com.cn
Country: China
ProdList: 306
Advantage: 60

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6719
Advantage: 55

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10287
Advantage: 55

Changzhou Yuanda Pharmaceutical Chemical Co., Ltd.

Tel: 0519-83984084
Fax: 0519-88776993
Email: sales@ydpharm.com
Country: China
ProdList: 119
Advantage: 60

Shanghai AECOM Biotechnology Co. , Ltd.

Tel: 021-021-20956531 18116226605
Fax: 021-20956532
Email: sui@neosunpharm.com
Country: China
ProdList: 350
Advantage: 55

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5950
Advantage: 50

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9767
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9972
Advantage: 58

Guangzhou Ciming Biological Technology Co., Ltd.

Tel: 020-38082199,29065168,38082986,29878298,29866629,4000192398
Fax: +86 (20)38082986
Country: China
ProdList: 831
Advantage: 60

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7715
Advantage: 55

FarmaSino Pharmaceuticals (Anhui) Co.,Ltd.

Tel: +86-18512541987
Fax: 0555-5963572
Email: hll@farmasino.com
Country: China
ProdList: 241
Advantage: 60

Anqing CHICO Pharmaceutical Co., Ltd.

Tel: 13585175604 13585175604
Fax: +86-25-52261140
Email: sales@chicopharm.com
Country: China
ProdList: 496
Advantage: 65

Wuhan Kai Lun new material Chemical Co Ltd

Tel: 025-87787262
Fax: 025-87787262
Country: China
ProdList: 496
Advantage: 58

Shanghai Synchem Pharma Co., ltd

Tel: 021-61984905-1 18016477331
Email: synchempharma@aliyun.com
Country: China
ProdList: 6454
Advantage: 55

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-50266790 Q3382968513
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 3168
Advantage: 55

CHMA Chemical Technology (Shanghai) Co., Ltd

Tel: 021-61556450 15800904410
Fax: 021-61556450
Country: China
ProdList: 2837
Advantage: 58

Jinan Putubio Tech Co., Ltd.

Tel: +86 (531) 8099-2215
Fax: +86 (531) 8099-2215
Email: putubio@outlook.com
Country: China
ProdList: 1261
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9638
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3496
Advantage: 58

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9934
Advantage: 55

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: order@changyanchem.com
Country: China
ProdList: 5008
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9604
Advantage: 55

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 1649
Advantage: 55

Less

View Lastest Price from 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- manufacturers

Changzhou Rokechem Technology Co., Ltd.

Product: 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4- morpholinyl)phenyl]-5- oxazolidinyl]methyl]-1H-isoindole- 1,3(2H)-dione 446292-08-6
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99%
Supply Ability: 1-10000kgs
Release date: 2023-05-25

Xinxiang Hongqi District Houyuan Trading Co.,Ltd

Product: 1H-ISOindole-1,3(2H) -Dione, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHolinyl)PHENYL] -5-OXAZolidinyl]METHYL]- 446292-08-6
Price: US $30.00-28.00/Kg
Min. Order: 1Kg
Purity: 99.0% up
Supply Ability: 50 tons per month
Release date: 2022-10-06

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione 446292-08-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

446292-08-6, 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-Related Search:

Rivaroxaban Metabolite 8 AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 2-ThiophenecarboxaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 5-R-Rivaroxaban Rivaroxaban POLYSTYRENE IODOSOACETATE 1,2-Cyclohexanedione (S)-(+)-Epichlorohydrin 4-(4-NITROPHENYL)MORPHOLIN-3-ONE (S)-(+)-Glycidyl Phthalimide 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE 5-Chloro-2-thiophenecarboxylic Acid m-(Trifluoromethyl)phenylacetic acid

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

(S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione

2-({(5S)-2-oxo-3-[4-(3-oxoMorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}Methyl)-1H-isoindole-1,3(2H)-dione

RivaroxabanInterMediates-01

4-[4-[(5S)-5-PhthaliMidoMethyl-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone

2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione

Rivaroxaban Intermediate5

Rivaroxaban Phthalimido Impurity

2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}

2 - [[(5S) -2- oxo-3- [4- (3-oxo - (morpholin-4-yl)) phenyl] -5-oxazolidinyl] methyl] lH- isoindole -1,3 (2H) - dione

2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

(R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione

Rivaroxaban ImpVI

Rivaroxaban impurity 4/2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione

2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dion

Rivaroxaban-5

Rivaroxaban G

(S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione (Rivaroxaban)

Rivaroxaban EP Impurity G

2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-1H-ISOINDOLE-1,3(2H)-DIONE CAS: 446292-08-6

Rivaroxaban PTH Imp/Rivaroxaban EP Impurity G

2-Amino-13-picoline

2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazoli...

Rivaroxaban Impurities365

Rivaroxaban EP Impurity GQ: What is Rivaroxaban EP Impurity G Q: What is the CAS Number of Rivaroxaban EP Impurity G Q: What is the storage condition of Rivaroxaban EP Impurity G Q: What are the applications of Rivaroxaban EP Impurity G

TIANFUCHEM--446292-08-6---1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

(S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazoli

4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone (or) 1H-isoindole-1,3 (2H)-Dione, 2-[[(5S)-2-Oxo-3-[4-(3-Oxo-4Morpholinyl)Phenyl]-5-Oxazolidinyl]methyl

2-[[(5S)-2-Oxo-3-[4-(3-oxo -4-morpholinyl)phenyl]-5-o xazolidinyl]methyl]-1H-isoi ndole-1,3(2H)

C22HjgNzO6

2- [(5S) -2-oxo-3- [4- (3-oxo-4-morphinyl) phenyl] -5-oxazolyl] methyl] -1H-isoindole-1,3 (2H) - dione

Intermediate of Rivaroxaban 3

446292-08-6

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Intermediate of Rivaroxaban