6-O-Benzylguanine

ChemicalBook > CAS DataBase List > 6-O-Benzylguanine

Product Name: 6-O-Benzylguanine
CAS No.: 19916-73-5
Chemical Name: 6-O-Benzylguanine
Synonyms: 6-benzylguanine;O6-BENZYLGUANINE;O6-Benzylguanine ,98%;6-(benzyloxy)-7H-purin-2-aMine;O6-BenzyL;NSC 637037;6-O-BENZYLGUANINE;6-BENZYLOXY GUANINE;6-oxo -benzylguanine;4 6-Benzyloxyguanine
CBNumber: CB9263934
Molecular Formula: C12H11N5O
Formula Weight: 241.25
MOL File: 19916-73-5.mol

Less

6-O-Benzylguanine Property

Melting point:: 193(dec.)
Boiling point:: 459.3±55.0 °C(Predicted)
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: methanol: 20 mg/mL
form: solid
pka: 7.47±0.20(Predicted)
color: Off-White to Light Yellow
CAS DataBase Reference: 19916-73-5(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B2292
Product name: O6-Benzylguanine
Purity: ≥98% (TLC), solid
Packaging: 50mg
Price: $107
Updated: 2024/03/01

Alfa Aesar

Product number: H60274
Product name: O6-Benzylguanine, 98%
Packaging: 250mg
Price: $47.65
Updated: 2024/03/01

Cayman Chemical

Product number: 16332
Product name: O6-Benzylguanine
Purity: ≥98%
Packaging: 10mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16332
Product name: O6-Benzylguanine
Purity: ≥98%
Packaging: 1g
Price: $699
Updated: 2024/03/01

Cayman Chemical

Product number: 16332
Product name: O6-Benzylguanine
Purity: ≥98%
Packaging: 50mg
Price: $56
Updated: 2024/03/01

Less

6-O-Benzylguanine Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.

Uses

O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Biochem/physiol Actions

O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma.

6-O-Benzylguanine Preparation Products And Raw materials

Raw materials

Acetonitrile N,N-Dimethylformamide Guanine Benzyl alcohol Tetraethylammonium Chloride 6-Chloroguanine Toluene Phosphorus oxychloride Ethyl acetate 1,2-Dichloroethane Hydrochloric acid Acetic acid Sodium hydroxide Activated carbon

Preparation Products

Less

6-O-Benzylguanine Suppliers

Canada 3 China 311 Czech Republic 1 Europe 2 Germany 5 India 12 South Korea 1 Switzerland 2 United Kingdom 11 United States 52 Global 400

Hunan Eurasian Pharmaceutical Co. Ltd.

Tel: 0592-5789919 13328776692
Email: 2851802016@qq.com
Country: China
ProdList: 66
Advantage: 58

Hubei Dingchengshijia Pharmaceutical Chemical Co.,Ltd

Tel: 027-50664927 13995564702
Email: 752154176@qq.com
Country: China
ProdList: 95
Advantage: 58

New Energy Chemicals

Tel: 0515-82159088 13770142076
Fax: 86-0515-8215909
Email: twl@njuchem.com
Country: China
ProdList: 205
Advantage: 65

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12458
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Yaqee Industrial Corporation Limited

Tel: +86-561-5269788, 5209788
Fax: +86-561-5209268
Country: China
ProdList: 40
Advantage: 66

Lianyungang Gabriel Bio-chem Technology Co., Ltd.

Tel: +86 (518) 8548-7361
Fax: +86 (518) 8561-1105
Email: lyggabriel@163.com
Country: China
ProdList: 20
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17987
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3296
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12990
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8618575662672 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9747
Advantage: 57

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 15343847665
Fax: QQ：3470079902
Email: huawenchem@163.com
Country: China
ProdList: 3206
Advantage: 55

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 010-53679529 13801208576
Fax: 010-64215766
Email: sales.2@chinazhongshuo.com
Country: China
ProdList: 97
Advantage: 65

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2893
Advantage: 58

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.

Tel: 18606289633 15862625988
Fax: 0512-58813106
Email: sales@clentchem.com
Country: China
ProdList: 192
Advantage: 60

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4687
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 021-50430803 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9352
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Nanjing Baifuli Technology Co., Ltd.

Tel: 25-25-58740604 15951658055
Fax: +86-25-58356858
Email: sales@unisyn.cn
Country: China
ProdList: 537
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

Sichuan Weibo Science and Technology Co., Ltd.

Tel: 028-87578473
Fax: +86 (28) 8757-8473
Email: ellnn@163.com
Country: China
ProdList: 50
Advantage: 60

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

Shanghai Medpep Co., Ltd

Tel: 021-65566949 13901795941
Fax: 86-21-51861665
Email: market@medpep.com
Country: China
ProdList: 176
Advantage: 66

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9906
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7876
Advantage: 55

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

RennoTech Co., Ltd.

Tel: 58353739
Fax: +86-25-58353700
Email: sales@rennotech.com
Country: China
ProdList: 95
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3924
Advantage: 50

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9986
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4928
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 1352-6885213 15637198702
Fax: 0371-63709726
Email: xpkchem@163.com
Country: China
ProdList: 3998
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Less

View Lastest Price from 6-O-Benzylguanine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 6-O-Benzylguanine 19916-73-5
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5ton
Release date: 2024-04-22

Henan Fengda Chemical Co., Ltd

Product: O6-Benzylguanine 19916-73-5
Price: US $122.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-11

airuikechemical co., ltd.

Product: O6-Benzylguanine 19916-73-5
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 20 tons
Release date: 2024-03-15

19916-73-5, 6-O-BenzylguanineRelated Search:

EC 2.6.1.2 6-Aminocaproic acid 2-Aminopurine Benzyltrimethylammonium chloride 6-Methoxyguanine Benzyl chloride 3-Aminophenol Tris(hydroxymethyl)aminomethane 6-Benzylaminopurine Glycine ALTRENOGEST Purine Guanine Acetaminophen Benzyltriethylammonium chloride 4-Methoxybenzylchloride Iminodibenzyl 6-Thioguanine

O(sup 6)benzylguanidine

O6-Benzylguanine ,98%

2-Amino-6-(benzyloxy)-9H-purine

6-(Benzyloxy)-1H-purin-2-amine

6-(benzyloxy)-7H-purin-2-aMine

6-(PhenylMethoxy)-9H-purin-2-aMine

NSC 637037

6-benzylguanine

6-oxo -benzylguanine

6-O-Benzylguanine(O6BG)

9H-Purin-2-amine,6-(phenylmethoxy)-

6-phenylmethoxy-7H-purin-2-amine

O6-BENZYLGUANINE

2-Amino-6-(benzyloxy)purine

2-amino-6-(phenylmethoxy)-9h-purine

Ganciclovir Impurity 12

6-O-BENZYLGUANINE

6-BENZYLOXY-9H-PURIN-2-AMINE

6-BENZYLOXY GUANINE

4 6-Benzyloxyguanine

6-BENZYLOXY GUANINE2-AMINO-6-BENZYLOXYPURINE

O6-BenzyL

2-((2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl dibenzoate

"2-Amino-6-(benzyloxy)purine, 2-Amino-6-(phenylmethoxy)-9H-purine"

19916-73-5

9916-73-5

Apoptosis and Cell Cycle

DNA Repair Regulators

DNA metabolism

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Alkylguanine-DNA alkyltransferase, mammalian DNA repair proteinApoptosis and Cell Cycle

DNA Repair Regulators

A to

DNA metabolism

Enzyme Inhibitors by Enzyme

Nucleotides and Nucleosides

Bases & Related Reagents

Nucleotides