6-O-Benzylguanine
- Product Name
- 6-O-Benzylguanine
- CAS No.
- 19916-73-5
- Chemical Name
- 6-O-Benzylguanine
- Synonyms
- 6-benzylguanine;O6-BENZYLGUANINE;O6-Benzylguanine ,98%;6-(benzyloxy)-7H-purin-2-aMine;O6-BenzyL;NSC 637037;6-O-BENZYLGUANINE;6-BENZYLOXY GUANINE;6-oxo -benzylguanine;4 6-Benzyloxyguanine
- CBNumber
- CB9263934
- Molecular Formula
- C12H11N5O
- Formula Weight
- 241.25
- MOL File
- 19916-73-5.mol
6-O-Benzylguanine Property
- Melting point:
- 193(dec.)
- Boiling point:
- 459.3±55.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- methanol: 20 mg/mL
- form
- solid
- pka
- 7.47±0.20(Predicted)
- color
- Off-White to Light Yellow
- CAS DataBase Reference
- 19916-73-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B2292
- Product name
- O6-Benzylguanine
- Purity
- ≥98% (TLC), solid
- Packaging
- 50mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- H60274
- Product name
- O6-Benzylguanine, 98%
- Packaging
- 250mg
- Price
- $47.65
- Updated
- 2024/03/01
- Product number
- 16332
- Product name
- O6-Benzylguanine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 16332
- Product name
- O6-Benzylguanine
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $699
- Updated
- 2024/03/01
- Product number
- 16332
- Product name
- O6-Benzylguanine
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $56
- Updated
- 2024/03/01
6-O-Benzylguanine Chemical Properties,Usage,Production
Chemical Properties
Light Yellow Solid
Uses
An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.
Uses
O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Biochem/physiol Actions
O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma.
6-O-Benzylguanine Preparation Products And Raw materials
Raw materials
Preparation Products
6-O-Benzylguanine Suppliers
View Lastest Price from 6-O-Benzylguanine manufacturers
- Product
- 6-O-Benzylguanine 19916-73-5
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5ton
- Release date
- 2024-04-22
- Product
- O6-Benzylguanine 19916-73-5
- Price
- US $122.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-11
- Product
- O6-Benzylguanine 19916-73-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 20 tons
- Release date
- 2024-03-15