Hyperforin . DCHA
- Product Name
- Hyperforin . DCHA
- CAS No.
- 238074-03-8
- Chemical Name
- Hyperforin . DCHA
- Synonyms
- Hyp-DCHA;C47H75NO4;Hyperforin . DCHA;Hyperforin (dicylcohexylammonium) salt;Hyperforin (stable Dicyclohexylammonium salt);Hyperforin (stable Dicyclohexylammonium salt)-RM;Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1);Hyperforin (dicyclohexylammonium) salt analytical standard;(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione;(1R,5S,6R,7S)-4-Hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione dicyclohexylamine
- CBNumber
- CB92650749
- Molecular Formula
- C47H75NO4
- Formula Weight
- 718.12
- MOL File
- 238074-03-8.mol
Hyperforin . DCHA Property
- storage temp.
- -20°C
- solubility
- DMSO: ≥10mg/mL
- form
- powder
- color
- white to off-white
Safety
- Hazard Codes
- C,N
- Risk Statements
- 22-34-50/53
- Safety Statements
- 26-36/37/39-45-60-61
- RIDADR
- UN 1759 8 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H400Very toxic to aquatic life
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1792
- Product name
- Hyperforin (dicyclohexylammonium) salt
- Packaging
- 1mg
- Price
- $353
- Updated
- 2024/03/01
- Product number
- 42891
- Product name
- Hyperforin (dicyclohexylammonium) salt
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $570
- Updated
- 2022/05/15
- Product number
- 19572
- Product name
- Hyperforin (dicyclohexylammonium salt)
- Purity
- ≥97%
- Packaging
- 500μg
- Price
- $134
- Updated
- 2024/03/01
- Product number
- 19572
- Product name
- Hyperforin (dicyclohexylammonium salt)
- Purity
- ≥97%
- Packaging
- 1mg
- Price
- $201
- Updated
- 2024/03/01
- Product number
- PHL89225
- Product name
- Hyperforin (stable Dicyclohexylammonium salt)
- Purity
- phyproof? Reference Substance
- Packaging
- 10mg
- Price
- $1000
- Updated
- 2024/03/01
Hyperforin . DCHA Chemical Properties,Usage,Production
Description
Hyperforin is a natural activator of the steroid X receptor (active at 0.1 to 0.5 μg/ml) and inhibitor of several cytochrome P450 (CYP) isoforms (IC50 = 10 μg/ml for CYP2D6). It can also inhibit microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50 = 1 μM), 5-lipoxygenase activating protein, and sirtuins.
Uses
Hyperforin Dicyclohexylammonium Salt is an inhibitor of monoamine uptake and TRPC6 agonist.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Stable salt of hyperforin. Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John′s wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake. It also is an activator of the pregnane X receptor (PXR), which serves as a key regulator of CYP3A4 transcription, a member of the cytochrome (CYP) P450 enzyme system. Recent studies have found other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.
storage
+4°C
Hyperforin . DCHA Preparation Products And Raw materials
Raw materials
Preparation Products
Hyperforin . DCHA Suppliers
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