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Hyperforin . DCHA

Product Name
Hyperforin . DCHA
CAS No.
238074-03-8
Chemical Name
Hyperforin . DCHA
Synonyms
Hyp-DCHA;C47H75NO4;Hyperforin . DCHA;Hyperforin (dicylcohexylammonium) salt;Hyperforin (stable Dicyclohexylammonium salt);Hyperforin (stable Dicyclohexylammonium salt)-RM;Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1);Hyperforin (dicyclohexylammonium) salt analytical standard;(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione;(1R,5S,6R,7S)-4-Hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione dicyclohexylamine
CBNumber
CB92650749
Molecular Formula
C47H75NO4
Formula Weight
718.12
MOL File
238074-03-8.mol
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Hyperforin . DCHA Property

storage temp. 
-20°C
solubility 
DMSO: ≥10mg/mL
form 
powder
color 
white to off-white
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Safety

Hazard Codes 
C,N
Risk Statements 
22-34-50/53
Safety Statements 
26-36/37/39-45-60-61
RIDADR 
UN 1759 8 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H400Very toxic to aquatic life

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H1792
Product name
Hyperforin (dicyclohexylammonium) salt
Packaging
1mg
Price
$353
Updated
2024/03/01
Sigma-Aldrich
Product number
42891
Product name
Hyperforin (dicyclohexylammonium) salt
Purity
analytical standard
Packaging
5mg
Price
$570
Updated
2022/05/15
Cayman Chemical
Product number
19572
Product name
Hyperforin (dicyclohexylammonium salt)
Purity
≥97%
Packaging
500μg
Price
$134
Updated
2024/03/01
Cayman Chemical
Product number
19572
Product name
Hyperforin (dicyclohexylammonium salt)
Purity
≥97%
Packaging
1mg
Price
$201
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL89225
Product name
Hyperforin (stable Dicyclohexylammonium salt)
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$1000
Updated
2024/03/01
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Hyperforin . DCHA Chemical Properties,Usage,Production

Description

Hyperforin is a natural activator of the steroid X receptor (active at 0.1 to 0.5 μg/ml) and inhibitor of several cytochrome P450 (CYP) isoforms (IC50 = 10 μg/ml for CYP2D6). It can also inhibit microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50 = 1 μM), 5-lipoxygenase activating protein, and sirtuins.

Uses

Hyperforin Dicyclohexylammonium Salt is an inhibitor of monoamine uptake and TRPC6 agonist.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Stable salt of hyperforin. Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John′s wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake. It also is an activator of the pregnane X receptor (PXR), which serves as a key regulator of CYP3A4 transcription, a member of the cytochrome (CYP) P450 enzyme system. Recent studies have found other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.

storage

+4°C

Hyperforin . DCHA Preparation Products And Raw materials

Raw materials

Preparation Products

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Hyperforin . DCHA Suppliers

China 44 France 1 United Kingdom 2 United States 9 Global 56
TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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Aladdin Scientific
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sales@aladdinsci.com
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United States
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United States Biological
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United States
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Cayman Chemical Company
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
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United States Biological
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chemicals@usbio.net
Country
United States
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Creative Enzymes
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MedChemExpress
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238074-03-8, Hyperforin . DCHARelated Search:

protopseudohypericin Hypericin PROTOHYPERICIN Original Hypericin Standard HYPERFORIN ADHYPERFORIN Pseudohypericin protohypericin HYPERICIN Hypericin Standard alpha-Terpineol alpha-Cyperone beta-Eudesmol Hydroxyecdysone 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one MOSLOFLAVONE (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one HYPERICINHYPERFORIN 2-[[5,7-Dihydroxy-8-(1-oxoisobutyl)-2,2-dimethyl-2H-1-benzopyran-6-yl]methyl]-3,5-dihydroxy-6-(1-oxoisobutyl)-4,4-dimethyl-2,5-cyclohexadien-1-one ADHYPERFORIN(SH)

  • Hyp-DCHA
  • Hyperforin (stable Dicyclohexylammonium salt)
  • Hyperforin . DCHA
  • C47H75NO4
  • Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1)
  • Hyperforin (dicylcohexylammonium) salt
  • Hyperforin (dicyclohexylammonium) salt analytical standard
  • N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
  • (1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
  • (1R,5S,6R,7S)-4-Hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione dicyclohexylamine
  • Hyperforin (stable Dicyclohexylammonium salt)-RM
  • 238074-03-8
  • C35H52O4C12H23N