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2-Chloro-4-methyl-3-nitropyridine

Product Name
2-Chloro-4-methyl-3-nitropyridine
CAS No.
23056-39-5
Chemical Name
2-Chloro-4-methyl-3-nitropyridine
Synonyms
2-Chloro-4-Methyl-3-NP;2-CHLORO-3-NITRO-4-PICOLINE;2-Chloro-3-nitro-4-picoline,98%;2-CHLORO-3-NITRO-4-METHYLPYRIDINE;2-CHLORO-4-METHYL-3-NITROPYRIDINE;3-Nitro-2-chloro-4-methylpyridine;2,Chloro-4-Methyl-3-3-nitropyridine;2-Chloro-4-methyl-3-nitropyridine>PYRIDINE, 2-CHLORO-4-METHYL-3-NITRO-;2-Chloro-4-methyl-3-nitropyridine 98+%
CBNumber
CB9304053
Molecular Formula
C6H5ClN2O2
Formula Weight
172.57
MOL File
23056-39-5.mol
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2-Chloro-4-methyl-3-nitropyridine Property

Melting point:
51-53 °C (lit.)
Boiling point:
279.6±35.0 °C(Predicted)
Density 
1.406±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
-1.80±0.10(Predicted)
form 
Powder
color 
Yellow to beige
Sensitive 
Hygroscopic
InChI
InChI=1S/C6H5ClN2O2/c1-4-2-3-8-6(7)5(4)9(10)11/h2-3H,1H3
InChIKey
JHARVUVBTAAPLA-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC(C)=C1[N+]([O-])=O
CAS DataBase Reference
23056-39-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-21/22
Safety Statements 
26-37/39-36/37/39-36
RIDADR 
UN2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
304360
Product name
2-Chloro-4-methyl-3-nitropyridine
Purity
99%
Packaging
1g
Price
$108
Updated
2023/01/07
TCI Chemical
Product number
C2012
Product name
2-Chloro-4-methyl-3-nitropyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
C2012
Product name
2-Chloro-4-methyl-3-nitropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$47
Updated
2024/03/01
Alfa Aesar
Product number
H26057
Product name
2-Chloro-4-methyl-3-nitropyridine, 97%
Packaging
1g
Price
$41
Updated
2021/12/16
Alfa Aesar
Product number
H26057
Product name
2-Chloro-4-methyl-3-nitropyridine, 97%
Packaging
5g
Price
$121
Updated
2021/12/16
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2-Chloro-4-methyl-3-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Chloro-4-methyl-3-nitropyridine is a cyclopropyldipyridodiazepinone derivative for use as non-nucleoside reverse transcriptase inhibitors.

Definition

2-Chloro-4-methyl-3-nitropyridine (2C4M3NP) is a nitropyridine derivative that could form an acceptor fragment of 2-adamantylamino-5-nitropyridine (AANP). This crystal shows a particularly large optical non-linearity. It is observed that the mean C-C (ring) bond distance calculated between the ring carbon atoms of 2C4M3NP is 1.387 Å. In X-ray data of pyridine, the mean C-C (ring) bond distance is 1.394 Å. The C-H bond distances are found to be 1.081 Å. The computed values of C-C (ring) and C-H are slightly higher than that of the experimental value. This is attributed to the substituents present in the pyridine. The C-C-C bond angle where the -Cl and -NO2 group is attached with the middle carbon is more than 120? while the C-C-C bond angle where the -CH3 is substituted is less than 120? in 2C4M3NP. The N-C-CH3 bond angle (116.3) is less than that of the C-C-CH3 (124.2) probably due to the weak hydrogen bond formed between the nitrogen and hydrogen of the methyl group[1].

General Description

Experimental FTIR and FT-Raman spectroscopic analysis of 2-chloro-4-methyl-3-nitropyridine was reported.

References

[1] Arjunan, V. , et al. "A comparative study on vibrational, conformational and electronic structure of 2-chloro-4-methyl-3-nitropyridine and 2-chloro-6-methylpyridine." Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy 92.none(2012):305-317.

2-Chloro-4-methyl-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-4-methyl-3-nitropyridine Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 2-Chloro-4-methyl-3-nitropyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Chloro-4-methyl-3-nitropyridine 23056-39-5
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Hebei Zhanyao Biotechnology Co. Ltd
Product
2-Chloro-4-methyl-3-nitropyridine 23056-39-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-15
Dideu Industries Group Limited
Product
2-Chloro-4-methyl-3-nitropyridine 23056-39-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-08

23056-39-5, 2-Chloro-4-methyl-3-nitropyridineRelated Search:


  • 2-Chloro-4-Methyl-3-NP
  • 2-CHLORO-4-METHYL-3-NITROPYRIDINE
  • 2-CHLORO-3-NITRO-4-METHYLPYRIDINE
  • 2-CHLORO-3-NITRO-4-PICOLINE
  • PYRIDINE, 2-CHLORO-4-METHYL-3-NITRO-
  • 2-CHLORO-3-NITRO-4-PICOLINE (2-CHLORO-4-METHYL-3-NITROPYRIDINE)
  • 3-Nitro-2-chloro-4-methylpyridine
  • 2-Chloro-3-nitro-4-picoline,98%
  • 2-Chloro-4-methyl-3-nitropyridine 98+%
  • 2,Chloro-4-Methyl-3-3-nitropyridine
  • 2-Chloro-4-methyl-3-nitropyridine&gt
  • 2-Chloro-4-methyl-3-nitropyridine ISO 9001:2015 REACH
  • 23056-39-5
  • C6H5ClN2O2
  • Pyridines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Halopyridines
  • Chloropyridines
  • Building Blocks
  • Non-nucleoside Reverse Transcriptase
  • Amines
  • Aromatics
  • Heterocycles
  • Pyridine
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Pyridine series
  • Heterocyclic Compounds
  • Pyridines
  • Chloropyridines
  • Halopyridines
  • Boronic Acid
  • C6Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Heterocycle-Pyridine series