SB-756050
- Product Name
- SB-756050
- CAS No.
- 447410-57-3
- Chemical Name
- SB-756050
- Synonyms
- SB-756050;SB-756050, >98%;SB756050;SB 756050;SB-756050;1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane;1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-;G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
- CBNumber
- CB93162605
- Molecular Formula
- C21H28N2O8S2
- Formula Weight
- 500.59
- MOL File
- 447410-57-3.mol
SB-756050 Property
- Boiling point:
- 653.1±65.0 °C(Predicted)
- Density
- 1.328±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.25 mg/ml; DMSO: 10 mg/ml
- form
- A crystalline solid
- pka
- -6.97±0.20(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27998
- Product name
- SB-756050
- Packaging
- 50mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 27998
- Product name
- SB-756050
- Packaging
- 100mg
- Price
- $208
- Updated
- 2024/03/01
- Product number
- 27998
- Product name
- SB-756050
- Packaging
- 10mg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- CS-6960
- Product name
- SB756050
- Purity
- 99.32%
- Packaging
- 10mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-6960
- Product name
- SB756050
- Purity
- 99.32%
- Packaging
- 25mg
- Price
- $135
- Updated
- 2021/12/16
SB-756050 Chemical Properties,Usage,Production
Description
SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.
SB-756050 Preparation Products And Raw materials
Raw materials
Preparation Products
SB-756050 Suppliers
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