ChemicalBook > CAS DataBase List > Taurodeoxycholic acid sodium salt

Taurodeoxycholic acid sodium salt

Product Name
Taurodeoxycholic acid sodium salt
CAS No.
1180-95-6
Chemical Name
Taurodeoxycholic acid sodium salt
Synonyms
SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
CBNumber
CB9349065
Molecular Formula
C26H44NNaO6S
Formula Weight
521.69
MOL File
1180-95-6.mol
More
Less

Taurodeoxycholic acid sodium salt Property

Melting point:
168 °C (dec.)(lit.)
alpha 
33 º (c=3, water)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow
form 
Solid
pka
1.9
color 
White to Off-White
Water Solubility 
soluble
InChIKey
YXHRQQJFKOHLAP-UROAIUCXNA-M
CAS DataBase Reference
1180-95-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
37
Safety Statements 
24/25
WGK Germany 
3
F 
3-10
HS Code 
29242990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
580221
Product name
Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem
Purity
Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A
Packaging
5G
Price
$211
Updated
2025/07/31
Sigma-Aldrich
Product number
580221
Product name
Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem
Purity
Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A
Packaging
50g
Price
$807
Updated
2025/07/31
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt)
Purity
≥95%
Packaging
1g
Price
$35
Updated
2021/12/16
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt)
Purity
≥95%
Packaging
5g
Price
$88
Updated
2021/12/16
Cayman Chemical
Product number
15935
Product name
Taurodeoxycholic Acid (sodium salt)
Purity
≥95%
Packaging
25g
Price
$350
Updated
2021/12/16
More
Less

Taurodeoxycholic acid sodium salt Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystalline powder

Uses

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

in vivo

Taurodeoxycholate (1.25-5 mg/kg, p.o., 6 days) sodium salt ameliorates dextran sodium sulfate (DSS)-induced colitis in mice[9].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 50 mg/kg; i.p.; once daliy for 34 d) prevents neuropathology and associated behavioral deficits in the 3-nitropropionic acid rat model of Huntington's disease (HD) [10].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 500 mg/kg; s.c.; once every 3 d for 7 weeks) leads to a significant reduction in striatal neuropathology of the R6/2 transgenic HD mouse[11].
Taurodeoxycholate (0.5 mg/kg; i.v., once) sodium salt confers protection to C57BL/6N mice with sepsis, but does not protect TGR5 KO mice under sepsis[12].

Animal Model:A mouse colitis model (fed with 3% (w/v) DSS in drinking water for the first seven days and then switched to normal drinking water for an additional two days)[9]
Dosage:1.25, 2.5, and 5 mg/kg
Administration:Oral gavage (p.o.), from day 3 to day 8, once a day
Result:Prevented loss of body weight, shortening of the colon, production of pro-inflammatory cytokines, infiltration of pro-inflammatory cells, and mucosal ulceration in the colon.
Animal Model:Huntington's disease model in mouse[10]
Dosage:50 mg/kg
Administration: Intraperitoneal injection; once daliy for 34 d, injected 3-NP at 6 hr after Taurodeoxycholic acid treatment
Result:Reduced striatal atrophy, decreased striatal apoptosis, as well as fewer and smaller size ubiquitinated neuronal intranuclear huntingtin inclusions.
Significantly improved locomotor and sensorimotor deficits.
Animal Model:C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis[12]
Dosage:0.5 mg/kg
Administration:Intravenous injection, 30 min or 24 h after LPS injection
Result:Improved the survival rate of mice with sepsis.
Decreased liver and kidney damage in septic mice.
Ameliorated systemic inflammation and normalized blood pressure in septic mice.

Purification Methods

The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]

Taurodeoxycholic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Taurodeoxycholic acid sodium salt Suppliers

Belgium 1 Canada 1 China 273 Germany 1 India 7 Japan 2 New Zealand 1 Switzerland 3 United Kingdom 7 United States 26 Global 322
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Cato Research Chemicals Inc.
Tel
+86-020-81960175-877 4000-868-328
Email
tianwen.zhan@cato-chem.com
Country
United States
ProdList
10404
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
EBRATOR BIOCHEMICALS,INC.
Tel
--
Fax
--
Email
sales@ebtbio.com
Country
United States
ProdList
577
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Cambridge Isotope Laboratories, Inc.
Tel
--
Fax
--
Email
cilsales@isotope.com
Country
United States
ProdList
6598
Advantage
79
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Aceto Corporation
Tel
--
Fax
--
Email
contact@aceto.com
Country
United States
ProdList
2619
Advantage
75
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Research Plus, Inc.
Tel
--
Fax
--
Email
respls@aol.com
Country
United States
ProdList
3674
Advantage
51
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Steraloids Inc.
Tel
--
Fax
--
Email
sales@steraloids.com
Country
United States
ProdList
2357
Advantage
68
More
Less

View Lastest Price from Taurodeoxycholic acid sodium salt manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
Taurodeoxycholic acid sodium salt 1180-95-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97%min
Supply Ability
2000KGS
Release date
2025-08-16
Anhuyan (Hainan) Biotechnology Co., LTD
Product
Taurodeoxycholic acid sodium salt 1180-95-6
Price
US $2.00/g
Min. Order
1g
Purity
99.99
Supply Ability
10000
Release date
2025-06-05
Shaanxi Xianhe Biotech Co., Ltd
Product
Sodium taurodeoxycholate 1180-95-6
Price
US $0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
1000KG
Release date
2025-04-22

1180-95-6, Taurodeoxycholic acid sodium saltRelated Search:

Taurine 2-aminoethanesulphonamide monohydrochloride GLYCOCHOLIC ACID SODIUM SALT Tauroursodeoxycholate Sodium deoxycholate TAUROCHOLIC ACID SODIUM SALT HYDRATE Tauroursodeoxycholic acid TAUROURSODEOXYCHOLIC ACID SODIUM SALT TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Sodium taurodeoxycholate hydrate TAUROHYODEOXYCHOLIC ACID SODIUM SALT Sodium taurocholate taurohyodeoxycholic acid Taurohyodeoxycholic acid sodium salt hydrate Taurodeoxycholic acid sodium salt SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Sodium cholate Sodium tauroglycocholate

  • TAURODEOXYCHOLIC ACID SODIUM
  • TAURODEOXYCHOLIC ACID SODIUM SALT
  • Taurodeoxycholic acid sodium salt hydrate
  • SODIUM TAURODEOXYCHOLATE
  • SODIUM TAURODEOXYCHOLATE SODIUM SALT
  • SODIUM TAURODESOXYCHOLATE SODIUM SALT
  • 2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT
  • 5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM
  • 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
  • 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
  • sodium 2-[[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
  • Ethanesulfonic acid, 2-(3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-ylamino-, monosodium salt
  • sodium taurodeoxylate
  • Ursodeoxycholic Impurity 16
  • sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
  • Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
  • Cholane, ethanesulfonic acid deriv.
  • Sodium deoxytaurocholate
  • Sodium taurodesoxycholate
  • Taurodeoxycholate sodium
  • Taurodeoxycholic acid sodium salt hydrate,97%
  • 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid sodium salt
  • 2-[(3α,12α-Dihydroxy-24-oxo-5β-cholane)-24-ylamino]ethanesulfonic acid sodium salt
  • 3α,12α-Dihydroxy-24-[[2-(sodiooxysulfonyl)ethyl]amino]-5β-cholane-24-one
  • N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)taurine sodium salt
  • N-[2-(Sodiooxysulfonyl)ethyl]-3α,12α-dihydroxy-5β-cholane-24-oic amide
  • Sodium tarurodeoxycholate
  • 2-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-ylamino)ethanesulfonic acid sodium salt
  • Sodium Taurodeoxycholic acid
  • Taurodeoxycholic acid sodium salt ,97%
  • Taurodeoxychloic Acid SodiuM Salt
  • SodiuM taurodeoxycholat
  • N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine MonosodiuM Salt
  • SodiuM 3α,12α-Dihydroxy-5β-cholanoyltaurate
  • SODIUM TAUROUSODEOXYCHOLATE
  • Taurodeoxycholate sodium salt
  • Ethanesulfonic Acid,2-[[(3A,5B,12A-3,12-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Monosodium Salt
  • Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate
  • Taurodeoxycholic acid sodium saltr
  • Taurodeoxycholic acid sodium salt ISO 9001：2015 REACH
  • Taurodeoxycholicacid (Crude)
  • sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-o...
  • Sodium taurodeoxycholate, hydrate, ≥95% (HPLC)
  • )-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
  • 12B1
  • 5B2
  • sodium 2-[[(3B1
  • Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97%
  • Urosodeoxycholic Acid Impurity 16
  • 5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
  • Sodium taurine deoxycholate
  • Taurodeoxycholate sodium salt, 10 mM in DMSO
  • Taurodeoxycholic Acid Sodium Salt (Sodium Taurodeoxycholate)
  • TAURODEOXYCHOLIC ACID SODIUM SALT-2,2,4,4-d4 ACID
  • 1180-95-6
  • C26H44NNaO6SxH2O
  • C26H44NO6S種a
  • Anionic