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Amlodipine

Product Name
Amlodipine
CAS No.
88150-42-9
Chemical Name
Amlodipine
Synonyms
AmL;Isti;LOTREL;Pelmec;besylate;UK-48340;AMlopres;Amlodipin;Intervask;AMLODIPINE
CBNumber
CB9366505
Molecular Formula
C20H25ClN2O5
Formula Weight
408.88
MOL File
88150-42-9.mol
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Amlodipine Property

Melting point:
178-179°C
Boiling point:
527.2±50.0 °C(Predicted)
Density 
1.227±0.06 g/cm3(Predicted)
RTECS 
US7968329
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
pKa 8.6 (Uncertain)
form 
Almost white crystal powder
Water Solubility 
75.3 mg/L
CAS DataBase Reference
88150-42-9(CAS DataBase Reference)
EPA Substance Registry System
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester (88150-42-9)
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Safety

HazardClass 
IRRITANT
HazardClass 
6.1
Hazardous Substances Data
88150-42-9(Hazardous Substances Data)
Toxicity
TDLo orl-chd: 400 mg/kg:BPR AJEMEN 18,581,2000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
1g
Price
$111
Updated
2021/03/22
Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
5g
Price
$422
Updated
2021/03/22
Cayman Chemical
Product number
14838
Product name
Amlodipine
Purity
≥98%
Packaging
5g
Price
$330
Updated
2021/03/22
Cayman Chemical
Product number
14838
Product name
Amlodipine
Purity
≥98%
Packaging
1g
Price
$88
Updated
2021/03/22
Alfa Aesar
Product number
J62242
Product name
Amlodipine, 97+%
Packaging
10g
Price
$550
Updated
2021/03/22
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Amlodipine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Uses

anti-hypertensive;calcium channel blocker

Uses

A deuterated dihydropyridine calcium channel blocker.;Application of Labeled APIs: Labeled Amlodipine, intended for use as an internal standard for the quantification of Amlodipine by GC- or LC-mass spectrometry.

Definition

ChEBI: A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

brand name

Norvasc (Pfizer).

General Description

Amlodipine, 2-[, for the treatment of hypertension. Amlodipineis also marketed as a combination therapy with atorvastatinunder the tradename Norvasc for the management of highcholesterol and high blood pressure.

Hazard

Human systemic effects.

Safety Profile

Human systemic effects. Whenheated to decomposition it emits toxic vapors of NOx andCl-.

Amlodipine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Amlodipine manufacturers

Jinan Ande Pharmaceutical Co.,Ltd.
Product
Amlodipine 88150-42-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500
Release date
2021-08-09
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Amlodipine 88150-42-9
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg/month
Release date
2021-11-26
Hebei Guanlang Biotechnology Co., Ltd.
Product
Amlodipine 88150-42-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-10-28

88150-42-9, AmlodipineRelated Search:


  • 3,5-pyridinedicarboxylicacid,1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor
  • Amlodipine base (crystalline)
  • (R)-3-ethyl 5-methyl 2
  • 3-ethyl5-methylester
  • LOTREL
  • methyl ethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • AMLODIPINE
  • AMLODIPINE BASE
  • Amlodipin
  • besylate
  • AMLODIPINE MM(CRM STANDARD)
  • Amlodipine&Int
  • AmlodipineBesylate/Maleate
  • 3,5-Pyridinedicarboxylic acid, 2-(2-aminoethoxy)methyl-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
  • ethyl methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Pelmec
  • Racemic Amlodipine
  • 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor 3-ethyl 5-methyl ester
  • 3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Amlodipine Besilate Imp.(EP)
  • 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl O5-methyl ester
  • Amlodipine besilate (JAN)
  • Amlodipine besylate (USAN)
  • Isti
  • O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Amlodipine, >=99%
  • (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • 4-(2-chloro-phenyl-2(3-(1,3-dioxo-l,3-dihydro-isoindol-2yl-prpionyl)6-methyl-pyridin3, 5-dicarboxylic acid-ethyl-ethyl ester 5-methyl ester (p-2) of RS amlodipine besylate
  • AMlodipine besylate, >95%
  • Amlodipine Besylate IMP
  • phytoxanthin
  • Amlodipine (base and/or unspecified salts)
  • AMLODIPINE (BASE & SALTS)
  • Amlodipine ( Amlodipine Benzenesulfonate)
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 5-methyl 3-ethyl ester
  • UK-48340
  • UK-48340-11
  • 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl ester
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
  • 2-Methyl-4-(2-chlorophenyl)-6-[[(2-aminoethyl)oxy]methyl]-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-ethyl ester
  • 4-(2-Chlorophenyl)-2-methyl-6-(2-aminoethoxymethyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-ethyl ester
  • 4-(2-Chlorophenyl)-6-methyl-2-(2-aminoethoxymethyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
  • 3-ethyl 5-Methyl (4S)-2-[(2-aMinoethoxy)Methyl]-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • AMlodipine(Norvasc)
  • AMlodiping Besylate
  • (R,S)-AMlodipine
  • AMlopres
  • Intervask
  • 2-((2-Aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
  • AMLODIPINE (RS)-3-ETHYL-5-METHYL-2[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE
  • AMlodipine-d4 Maleate
  • [2H4]-Amlodipine besylate
  • AmL
  • odipine besyL
  • Amlodipine Solution in Methanol, 100μg/mL
  • Amlodipine USP/EP/BP
  • 88150-42-9
  • 38150-49-9