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2-Fluoro-3-nitrobenzoic acid

Product Name
2-Fluoro-3-nitrobenzoic acid
CAS No.
317-46-4
Chemical Name
2-Fluoro-3-nitrobenzoic acid
Synonyms
2-FLUORO-3-NITROBENZOIC ACID;Benzoic acid,2-fluoro-3-nitro-;3-Carboxy-2-fluoronitrobenzene;2-Fluoro-3-nitrobenzoic acid 99%;2-Fluoro-3-nitrobenzoic acid+B244;3-Pyridinecarboxylic acid, 4-aMino-
CBNumber
CB9412637
Molecular Formula
C7H4FNO4
Formula Weight
185.11
MOL File
317-46-4.mol
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2-Fluoro-3-nitrobenzoic acid Property

Melting point:
138 - 140°C
Boiling point:
347.6±27.0 °C(Predicted)
Density 
1.568±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
2.32±0.20(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
Slightly soluble in water.
Sensitive 
Air Sensitive
Stability:
Hygroscopic
InChI
InChI=1S/C7H4FNO4/c8-6-4(7(10)11)2-1-3-5(6)9(12)13/h1-3H,(H,10,11)
InChIKey
WLGUSLGYTNJJFV-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=CC([N+]([O-])=O)=C1F
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H63235
Product name
2-Fluoro-3-nitrobenzoic acid, 97%
Packaging
1g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
H63235
Product name
2-Fluoro-3-nitrobenzoic acid, 97%
Packaging
5g
Price
$115.65
Updated
2024/03/01
TRC
Product number
F621923
Product name
2-Fluoro-3-nitrobenzoicAcid
Packaging
5g
Price
$75
Updated
2021/12/16
TRC
Product number
F621923
Product name
2-Fluoro-3-nitrobenzoicAcid
Packaging
10g
Price
$90
Updated
2021/12/16
AK Scientific
Product number
X4498
Product name
2-Fluoro-3-nitrobenzoicacid
Packaging
25g
Price
$101
Updated
2021/12/16
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2-Fluoro-3-nitrobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow crystalline powder

Uses

2-Fluoro-3-nitrobenzoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

Concentrated sulfuric acid (195 ml) was added carefully and stirred to a solution of 2-fluoro-3-nitrotoluene (100 g, 645 mmol) in acetic acid (1000 ml). The mixture was warmed up to 95° C. The chromium trioxide solution (226 g, 2.25 mol) in water (200 ml) was added dropwise while stirring for over 2 h. After addition, the mixture was heated by stirring for another 3 h, allowed to cool down to room temperature, and poured into water (3 L). The mixture was extracted with ethyl acetate (3.x.1 L), the combined organic layers were dried over Na2SO4and concentrated under reduced pressure to afford a light green solid, which was washed with dichloromethane (3.x.300 ml) and dried under vacuum to afford 2-Fluoro-3-nitrobenzoic acid was obtained as a light yellow solid (75 g, 62.8percent). 1H NMR (300 MHz, DMSO) δ ppm 8.27 (m, 1H), 8.15 (m, 1H), 7.48 (m, 1H).

2-Fluoro-3-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluoro-3-nitrobenzoic acid Suppliers

Atlantic Research Chemicals Ltd.
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United Kingdom
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Apollo Scientific Ltd.
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Apin Chemicals Limited (UK)
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Eurolabs Limited
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Apin Chemicals Ltd.
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United Kingdom
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View Lastest Price from 2-Fluoro-3-nitrobenzoic acid manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-FLUORO-3-NITROBENZOIC ACID 317-46-4
Price
US $20.00-6.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
3 tons
Release date
2023-10-24
Hebei Mojin Biotechnology Co.,Ltd
Product
2-FLUORO-3-NITROBENZOIC ACID 317-46-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-09
Hebei Mojin Biotechnology Co., Ltd
Product
2-FLUORO-3-NITROBENZOIC ACID 317-46-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-10