ChemicalBook > CAS DataBase List > Doxylamine succinate

Doxylamine succinate

Product Name
Doxylamine succinate
CAS No.
562-10-7
Chemical Name
Doxylamine succinate
Synonyms
unisom;decapryn;hoggarn;alsadorm;gittalun;sedaplus;mereprine;DoxylaMineSuccinat;Decapryn succinate;DOXYLAMINE SUCCINATE
CBNumber
CB9416701
Molecular Formula
C21H28N2O5
Formula Weight
388.46
MOL File
562-10-7.mol
More
Less

Doxylamine succinate Property

Melting point:
95-98?C
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Very soluble in water, freely soluble in ethanol (96 per cent).
form 
Solid
color 
White to Off-White
Stability:
Stable, but may be light sensitive. Incompatible with strong oxidizing agents, acids, bases.
InChI
InChI=1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
InChIKey
KBAUFVUYFNWQFM-UHFFFAOYSA-N
SMILES
C(C)(OCCN(C)C)(C1=NC=CC=C1)C1C=CC=CC=1.C(C(=O)O)CC(=O)O
LogP
2.519 (est)
CAS DataBase Reference
562-10-7(CAS DataBase Reference)
IARC
3 (Vol. 79) 2001
EPA Substance Registry System
Doxylamine succinate (1:1) (562-10-7)
More
Less

Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-36/37/38-20/21/22-39/23/24/25-23/24/25-11
Safety Statements 
26-36/37-45-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
2
RTECS 
US9275000
HS Code 
2933399090
Toxicity
LD50 in mice, rabbits (mg/kg): 470, 250 orally; 62, 49 i.v.; in mice, male rats, female rats (mg/kg): 460, 440, 445 s.c. (Brown, Werner)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001562
Product name
Doxylamine hydrogen succinate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
60 mg
Price
$228
Updated
2025/07/31
Sigma-Aldrich
Product number
Y0001492
Product name
Doxylamine for system suitability
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
110 mg
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
D-045
Product name
Doxylamine succinate solution
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$51
Updated
2025/07/31
Sigma-Aldrich
Product number
1227006
Product name
Doxylamine succinate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
300mg
Price
$425
Updated
2025/07/31
TCI Chemical
Product number
D5583
Product name
Doxylamine Succinate
Packaging
5G
Price
$30
Updated
2025/07/31
More
Less

Doxylamine succinate Chemical Properties,Usage,Production

Chemical Properties

white to light cream powder

Uses

antihistaminic, hypnotic

Uses

Doxylamine succinate salt has been used as a therapeutic drug to check developmental toxicity.

Uses

H1 Histamine receptor antagonist. Antihistaminic; sedative; hypnotic.

Definition

ChEBI: Doxylamine succinate is an organic molecular entity.

brand name

Decapryn (Sanofi Aventis); Unisom (Pfizer).

General Description

The acid succinate salt (bisuccinate)of doxylamine, 2-[ -[2-(dimethylamino)ethoxy]- -methylbenzyl]pyridine bisuccinate (Decapryn Succinate), isa white to creamy-white powder with a characteristic odor.It is soluble in water (1:1), alcohol (1:2), and chloroform(1:2). A 1% solution has a pH of about 5.Doxylamine succinate is comparable in potency todiphenhydramine. It is indicated for the relief of seasonalrhinitis symptoms, but is also used as a nighttime sedative.Concurrent use of alcohol and other CNS depressantsshould be avoided.

General Description

White or creamy white powder. pH (1% aqueous solution) between 4.9 and 5.1.

Air & Water Reactions

Water soluble.

Health Hazard

SYMPTOMS: Symptoms of exposure to Doxylamine succinate may include drowsiness, excitability, nervousness, dizziness and sleeplessness.

Fire Hazard

Flash point data for Doxylamine succinate are not available. Doxylamine succinate is probably combustible.

Biochem/physiol Actions

H1 histamine receptor antagonist; hypnotic.Doxylamine suppresses histamine at the H1 receptor. It is associated with the short term management of insomnia and temporary relief of common cold symptoms. On the other hand, doxylamine intoxication is linked with rhabdomyolysis and secondary acute renal failure.Studies in mice show that doxylamine induces liver microsomal cytochrome P450 and other enzymes involved in thyroxine (T4) metabolism. In combination with pyridoxine hydrochloride, this drug is used to treat morning sickness.

Doxylamine succinate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Doxylamine succinate Suppliers

Americas 1 Belgium 1 Canada 4 China 196 Europe 3 Finland 1 France 1 Germany 9 India 91 Italy 2 Japan 1 Poland 1 Singapore 1 Spain 2 Switzerland 1 The Netherlands 1 United Kingdom 6 United States 39 Venezuela 1 Global 362
Jai Radhe Sales
Tel
+(91)-(79)-26431096/65255722
Fax
+(91)-(79)-26569884
Email
info@jairadhesales.com
Country
India
ProdList
397
Advantage
60
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
HONOUR LAB LTD
Tel
--
Fax
--
Email
info@honourlab.com
Country
India
ProdList
39
Advantage
58
Jayco Chemical Industries.
Tel
--
Fax
--
Email
info@jaycochemicals.com
Country
India
ProdList
10
Advantage
58
Sibram Pharmaceutical
Tel
--
Fax
--
Email
contact@sibram.com
Country
India
ProdList
136
Advantage
58
Vision Drugs Pvt. Ltd.
Tel
--
Fax
--
Email
mitra@visiondrugs.co.in
Country
India
ProdList
23
Advantage
58
Eastern Chemicals (Mumbai) Pvt., Ltd.
Tel
--
Fax
--
Email
info@ecmpl.com
Country
India
ProdList
104
Advantage
58
Cemex Pharma
Tel
--
Fax
--
Email
info@cemexpharma.com
Country
India
ProdList
21
Advantage
58
Vishal Pharma (Agency)
Tel
--
Fax
--
Email
info@vishalpharma.co.in
Country
India
ProdList
89
Advantage
58
Shreeji Pharma International
Tel
--
Fax
--
Country
India
ProdList
166
Advantage
58
Luconic Chemicals
Tel
--
Fax
--
Country
India
ProdList
72
Advantage
58
Novas International
Tel
--
Fax
--
Email
info@novasinternational.com
Country
India
ProdList
210
Advantage
58
BIOXERA PHARMA PRIVATE LTD
Tel
--
Fax
--
Email
info@bioxerapharma.com
Country
India
ProdList
9
Advantage
58
Nivon Specialties (India)
Tel
--
Fax
--
Email
info@nivonindia.com
Country
India
ProdList
154
Advantage
58
Abil Chempharma Pvt. Ltd.
Tel
--
Fax
--
Email
exports@abilchempharma.in
Country
India
ProdList
38
Advantage
58
Ayon PharmaChem
Tel
--
Fax
--
Email
bhargav@ayonpharmachem.com
Country
India
ProdList
303
Advantage
58
Vyshno Bio Sciences
Tel
--
Fax
--
Email
info@vyshnobio.com
Country
India
ProdList
239
Advantage
58
Dazzle Corporation
Tel
--
Fax
--
Email
enquiry@dazzlecorporation.co.in
Country
India
ProdList
209
Advantage
58
Sign Pharma Trade Services Pvt., Ltd.(SPTS)
Tel
--
Fax
--
Email
info@signpharma.com
Country
India
ProdList
160
Advantage
58
Pragati Raw Pharma Pvt., Ltd.
Tel
--
Fax
--
Country
India
ProdList
18
Advantage
58
Medvance Solution
Tel
--
Fax
--
Email
info@medvancesolutions.com
Country
India
ProdList
137
Advantage
58
Royal Trading Corporation
Tel
--
Fax
--
Country
India
ProdList
135
Advantage
58
Prism Consultancy
Tel
--
Fax
--
Email
info@prismconsultancy.biz
Country
India
ProdList
66
Advantage
58
Athos Chemicals
Tel
--
Fax
--
Email
export@athoschemicals.com
Country
India
ProdList
315
Advantage
58
Unnati Pharmaceuticals Pvt. Ltd.
Tel
--
Fax
--
Email
unnatipharma@gmail.com
Country
India
ProdList
86
Advantage
58
Vivimed Labs Ltd.
Tel
--
Fax
--
Email
info@vivimedlabs.com
Country
India
ProdList
32
Advantage
58
Global Chem Asia Pacific
Tel
--
Fax
--
Email
ghu@globalchem.in
Country
India
ProdList
255
Advantage
58
Lakshmi Farmachem
Tel
--
Fax
--
Email
info@lakshmifarmachem.com
Country
India
ProdList
44
Advantage
58
Anugraha Chemicals
Tel
--
Fax
--
Country
India
ProdList
11
Advantage
58
Clearsynth Labs
Tel
--
Fax
--
Email
fo@clearsynth.com
Country
India
ProdList
3887
Advantage
58
Chempro Pharma Pvt. Ltd.
Tel
--
Fax
--
Email
ankitsehgal@chemprogroup.net
Country
India
ProdList
170
Advantage
58
Ralington Pharma
Tel
--
Fax
--
Email
info@ralingtonpharma.com
Country
India
ProdList
312
Advantage
58
Rawia International HealthCare Pvt. Ltd.
Tel
--
Fax
--
Email
info@rawia.in
Country
India
ProdList
170
Advantage
58
Murli Krishna Exports Private Ltd.
Tel
--
Fax
--
Email
sales@mkepl.com
Country
India
ProdList
56
Advantage
58
Vipul Drugs Pvt., Ltd.
Tel
--
Fax
--
Country
India
ProdList
102
Advantage
58
Pharma Chemicals
Tel
--
Fax
--
Country
India
ProdList
130
Advantage
58
Aruvi Labs
Tel
--
Fax
--
Email
info@aruvilabs.com
Country
India
ProdList
68
Advantage
58
Aadivighnesh Chem Private Ltd.
Tel
--
Fax
--
Email
sales@aadivighnesh.com
Country
India
ProdList
119
Advantage
58
Esschem Pvt., Ltd.
Tel
--
Fax
--
Email
esschem@vsnl.com
Country
India
ProdList
96
Advantage
58
Rivashaa Agrotech Biopharma Pvt. Ltd.
Tel
--
Fax
--
Email
source@rivashaa.com
Country
India
ProdList
986
Advantage
58
Viraj Pharmaceuticals Pvt. Ltd.
Tel
--
Fax
--
Email
virajppl@gmail.com
Country
India
ProdList
162
Advantage
58
Placid Pharmachem
Tel
--
Fax
--
Email
parikshitjain@vsnl.com
Country
India
ProdList
115
Advantage
58
Shubham Pharmachem Pvt., Ltd.
Tel
--
Fax
--
Email
shubham@shubham.co.in
Country
India
ProdList
97
Advantage
58
Albios Lifesciences Private Limited
Tel
--
Fax
--
Email
info@albioslifesciences.com
Country
India
ProdList
51
Advantage
58
Aril Pharmaceuticals (Aril Biosciences Pvt. Ltd.)
Tel
--
Fax
--
Email
marketing@arilpharmaceuticals.com
Country
India
ProdList
67
Advantage
58
Samex Overseas
Tel
--
Fax
--
Country
India
ProdList
124
Advantage
58
SPB Pharma Chiemimpex
Tel
--
Fax
--
Email
sales@spbpharmachem.com
Country
India
ProdList
94
Advantage
58
Pharmaffiliates Analytics & Synthetics (P) Ltd.
Tel
--
Fax
--
Email
g@pharmaffiliates.com
Country
India
ProdList
631
Advantage
58
More
Less

View Lastest Price from Doxylamine succinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Doxylamine succinate 562-10-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2021-07-23
Baoji Guokang Healthchem Co., Ltd.
Product
Doxylamine succinate 562-10-7
Price
US $483.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000Kg
Release date
2021-06-03
Hebei Yanxi Chemical Co., Ltd.
Product
Doxylamine succinate 562-10-7
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-08

562-10-7, Doxylamine succinateRelated Search:

Metroprolol succinate DOXYLAMINE Dimethyl sulfate iron succinate Dimethyl carbonate Dimethyl ether Succinic acid Dimethyl fumarate Chlorodimethylphenylsilane ETHANE Disodium succinate Dimethyl sulfoxide Ethoxyquin 6alpha-Methylprednisolone sodium succinate Dimethyl sulfide N,N-Dimethylformamide 1-PYRIDIN-2-YL-ETHANOL 1-PHENYL-1-(2-PYRIDYL)ETHANOL

  • LABOTEST-BB LT00244822
  • DOXYLAMINE SUCCINATE
  • DOXYLAMINE SUCCINATE SALT
  • 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-pyridinsuccinate(1
  • 2-(alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl)pyridinesuccinate
  • 2-dimethylaminoethoxyphenylmethyl-2-picolinesuccinate
  • alsadorm
  • decapryn
  • decarpynsuccinate(1:1)
  • dimethylaminoethoxy-methyl-benzyl-pyridinesuccinate
  • DoxylaMineSuccinat
  • Doxylamine Succinate (300 mg)
  • Decapryn succinate
  • DOXYLAMINESUCCINATE,USP
  • N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)ethanamine
  • Doxylaminhydrogensuccinat
  • N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine succinate
  • DOXLAMINE SUCCINATE USP
  • [(3-carboxypropanoyl)oxy]diMethyl{2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl}aMinyl
  • Butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)
  • Doxylamine for system suitability
  • Doxylamine succinate solution
  • doxylaminesuccinate(1:1)
  • gittalun
  • hoggarn
  • mereprine
  • phenyl2-pyridylmethyl-beta-n,n-dimethylaminoethylethersuccinate
  • sedaplus
  • unisom
  • N,N-DIMETHYL-2-[1-PHENYL-1-(2-PYRIDINYL)ETHOXY]ETHENAMINE SUCCINATE
  • Doxylamine hydrogen succinate CRS
  • Doxylamine for system suitability CRS
  • Doxylaminesuccinatesal
  • N,N-Dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine Succinate
  • Doxylamine succinate USP/EP/BP
  • doxl amine succinate
  • Doxylamine succinateQ: What is Doxylamine succinate Q: What is the CAS Number of Doxylamine succinate Q: What is the storage condition of Doxylamine succinate Q: What are the applications of Doxylamine succinate
  • Doxylamine Succinate (1227006)
  • Docylamine succinate
  • N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine (Doxylamine succinate)
  • Butanedioic acid, compd. withN,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)OTHER CA INDEX NAMES:Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-,butanedioate (1:1)
  • Doxylamine succinate in methanol
  • Doxylamine succinate, 10 mM in DMSO
  • Doxylamine Hydrogen Succinate 1.0 mg/ml in Methanol (as free base)
  • Doxylamine.succinate, 1mg/ml in Methanol (as free base)
  • 562-10-7
  • C17H22N2OC4H6O4
  • API
  • DECAPRYN
  • Other APIs
  • Antagonists
  • Histaminergics
  • Neurotransmitters
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals