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Methyl 2-methoxy-5-sulfamoylbenzoate

Product Name
Methyl 2-methoxy-5-sulfamoylbenzoate
CAS No.
33045-52-2
Chemical Name
Methyl 2-methoxy-5-sulfamoylbenzoate
Synonyms
Sulpride Impurity B;Methyl2-Methoxy-5-S;Sulpiride EP Impurity B;Sulpiride Impurity B(EP);Sulpiride impurity B CRS;2-Methoxy-5-sulfamoylbenzoic;methyl 5-sulphamoyl-o-anisate;Sulpiride impurity B (S2192000);Methyl[5-Amino Sulfonyl-2-Methoxy];Methyl 2-Methoxy-5-sulphamoylbenzoa
CBNumber
CB9455786
Molecular Formula
C9H11NO5S
Formula Weight
245.25
MOL File
33045-52-2.mol
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Methyl 2-methoxy-5-sulfamoylbenzoate Property

Melting point:
175-177 °C (lit.)
Boiling point:
439.8±55.0 °C(Predicted)
Density 
1.360±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.94±0.60(Predicted)
color 
White to Off-White
LogP
0.36
CAS DataBase Reference
33045-52-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S2192000
Product name
Sulpiride impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
s2192000
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
522279
Product name
Methyl 2-methoxy-5-sulfamoylbenzoate
Purity
98%
Packaging
25g
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
M1942
Product name
Methyl 5-(Aminosulfonyl)-2-methoxybenzoate
Purity
>98.0%(HPLC)
Packaging
25g
Price
$80
Updated
2021/12/16
Apolloscientific
Product number
OR3568
Product name
Methyl5-(aminosulphonyl)-2-methoxybenzoate
Packaging
25g
Price
$19
Updated
2021/12/16
SynQuest Laboratories
Product number
8669-1-Z4
Product name
Methyl 5-(aminosulfonyl)-2-methoxybenzoate
Packaging
25g
Price
$21
Updated
2021/12/16
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Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties,Usage,Production

Uses

Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.

Preparation

Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.

synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate

General Description

Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.

Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-methoxy-5-sulfamoylbenzoate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
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Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
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57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
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View Lastest Price from Methyl 2-methoxy-5-sulfamoylbenzoate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Fengqiang Trading Co., LTD
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-07
Hebei Mojin Biotechnology Co., Ltd
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-28

33045-52-2, Methyl 2-methoxy-5-sulfamoylbenzoateRelated Search:


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