3-Pyridineacrylic acid

Product Name: 3-Pyridineacrylic acid
CAS No.: 1126-74-5
Chemical Name: 3-Pyridineacrylic acid
Synonyms: 3-(3-PYRIDYL)ACRYLIC ACID;Pyridine-3-acrylic acid;AKOS AUF2066;RARECHEM BK HC S246;3-Pyridineacrylicaci;3-PYRIDYLACRYLIC ACID;3-PYRIDINEACRYLIC ACID;3-Pyridylpropionic acid;3-PYRIDINYL-ACRYLIC ACID;B-(3-PYRIDYL)ACRYLIC ACID
CBNumber: CB9699461
Molecular Formula: C8H7NO2
Formula Weight: 149.15
MOL File: 1126-74-5.mol

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3-Pyridineacrylic acid Property

Melting point:: 232-235 °C (dec.)(lit.)
Boiling point:: 270.21°C (rough estimate)
Density: 1.2517 (rough estimate)
refractive index: 1.5320 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 3.13±0.10(Predicted)
form: Solid
color: White
InChI: InChI=1S/C8H7NO2/c10-8(11)4-3-7-2-1-5-9-6-7/h1-6H,(H,10,11)
InChIKey: VUVORVXMOLQFMO-UHFFFAOYSA-N
SMILES: C(O)(=O)C=CC1=CC=CN=C1
CAS DataBase Reference: 1126-74-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36-37/39-36/37/39
WGK Germany: 3
F: 10
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P1157
Product name: 3-(3-Pyridyl)acrylic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $32
Updated: 2025/07/31

TCI Chemical

Product number: P1157
Product name: 3-(3-Pyridyl)acrylic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $106
Updated: 2025/07/31

TRC

Product number: P991285
Product name: 3-PyridineacrylicAcid
Packaging: 2.5g
Price: $110
Updated: 2021/12/16

Matrix Scientific

Product number: 038635
Product name: (2E)-3-Pyridin-3-ylacrylic acid
Packaging: 5g
Price: $32
Updated: 2021/12/16

AK Scientific

Product number: CS-0031477
Product name: 3-(3-Pyridinyl)acrylicacid
Packaging: 25g
Price: $76
Updated: 2021/12/16

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3-Pyridineacrylic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

3-Pyridineacrylic Acid is an inhibitor of peptidylglycine amidating monooxygenase.

Synthesis

100390-47-4

19337-97-4

To a solution of butyl 3-(pyridin-3-yl)prop-2-enoate (70 g, 341 mmol, 1.00 equiv) in ethanol (150 mL) was added a solution of potassium hydroxide (40 g, 712.94 mmol, 2.09 equiv) in water (150 mL). The reaction mixture was stirred at room temperature for 20 hours. Upon completion of the reaction, the pH of the solution was adjusted to 6 with 12 M hydrochloric acid.The precipitate was collected by filtration to give 50 g (98% yield) of trans-3-(3-pyridyl)acrylic acid as an off-white solid.LCMS analysis (Method C, electrospray ionization, m/z): retention time = 0.78 min, m/z = 149.9 [M+H]+.

References

[1] Patent: WO2014/74715, 2014, A1. Location in patent: Paragraph 0170
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 3, p. 770 - 792

3-Pyridineacrylic acid Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Toluene Tetrahydrofuran 3-Pyridyl bromide Pyridine n-Butyllithium Malonic acid

Preparation Products

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3-Pyridineacrylic acid Suppliers

Americas 1 CHINA 132 Europe 1 Germany 5 India 9 Japan 1 Switzerland 2 Ukraine 1 United Kingdom 15 United States 32 Global 199

LEWOO PHARMATECH (SHANGHAI) CO.,LTD

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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Beijing Donghualituo Techonlogy Development Co.,Ltd.

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Email: sales@dhltchem.com
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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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View Lastest Price from 3-Pyridineacrylic acid manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 3-Pyridineacrylic acid 1126-74-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-06-11

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Pyridineacrylic acid 1126-74-5
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-07-14

Career Henan Chemical Co

Product: 3-Pyridineacrylic acid 1126-74-5
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

1126-74-5, 3-Pyridineacrylic acidRelated Search:

Acrylic acid Poly(acrylic acid) 3-Aminopyridine Methacrylic acid 2-Chloro-3-cyanopyridine Methyl acrylate Methyl methacrylate 6-Benzylaminopurine Folic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid ETHOXYLATED BISPHENOL A DIACRYLATE 3-(2-Amino-5-bromo-3-pyridyl)acrylic acid 3-(4-AMINO-3-PYRIDYL)ACRYLIC ACID 3-(2-PYRIDYL)ACRYLIC ACID,2-Pyridineacrylic acid,3-(2-PYRIDYL)ACRYLIC ACID 98% Urocanic acid 3-(5-BROMO-2-METHOXY-3-PYRIDYL)ACRYLIC ACID

3-PYRIDINYL-ACRYLIC ACID

3-(3-Pyridinyl)acrylic acid

Pyridine-3-acrylic acid

3-(3-Pyridyl)acrylic acid,99%

RARECHEM BK HC S246

TRANS-3-(3'-PYRIDYL)ACRYLIC ACID

TRANS-3-(3-PYRIDYL)ACRYLIC ACID

3-(pyridin-3-yl)prop-2-enoic acid

B-(3-PYRIDYL)ACRYLIC ACID

3-PYRIDINEACRYLIC ACID

3-PYRIDYLACRYLIC ACID

3-PYRIDIN-3-YL-ACRYLIC ACID

AKOS AUF2066

(2E)-3-PYRIDIN-3-YLACRYLIC ACID

3-(3-PYRIDYL)ACRYLIC ACID

3-(3-Pyridyl)acrylicAcid&gt

2-Propenoic acid, 3-(3-pyridinyl)-

3-Pyridineacrylicaci

3-Pyridylpropionic acid

1126-74-5

C8H7NO2

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