TDZD-8

Product Name
TDZD-8
Chemical Name
TDZD-8
Synonyms
TDZD-8;GSK-3BETA INHIBITOR I;4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE
CBNumber
CB9702181
Molecular Formula
C10H10N2O2S
Formula Weight
222.26
MOL File
Mol file
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TDZD-8 Property

Melting point:
63-64.4 °C
storage temp. 
2-8°C
solubility 
DMSO: 18 mg/mL
form 
needles
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J64048
Product name
GSK-3beta Inhibitor I
Packaging
5mg
Price
$108
Updated
2021/12/16
Usbiological
Product number
B1078-01E
Product name
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Packaging
10mg
Price
$333
Updated
2021/12/16
Biorbyt Ltd
Product number
orb146107
Product name
TDZD-8
Purity
>98%
Packaging
100mg
Price
$615.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb146107
Product name
TDZD-8
Purity
>98%
Packaging
1g
Price
$1949.9
Updated
2021/12/16
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TDZD-8 Chemical Properties,Usage,Production

Uses

A thiadiazolidinone (TDZD) analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3

Uses

Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).

TDZD-8 Preparation Products And Raw materials

Raw materials

Preparation Products

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TDZD-8 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
861
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5738
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
3501
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1836
Advantage
55
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4880
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10523
Advantage
58
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View Lastest Price from TDZD-8 manufacturers

Career Henan Chemical Co
Product
TDZD-8 7036-89-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23