Methyl 3-hydroxypropanoate

Product Name: Methyl 3-hydroxypropanoate
CAS No.: 6149-41-3
Chemical Name: Methyl 3-hydroxypropanoate
Synonyms: propanoic acid, 3-hydroxy-, methyl ester;HOCH2CH2C(O)OCH3;Methyl hydracrylate;Methyl3-hydroxypropionate;METHYL 3-HYDROXYPROPANOATE;Methyl beta-hydroxypropionate;Methyl gamma-hydroxypropionate;Hydracrylic acid, methyl ester;METHYL 3-HYDROXYPROPANOATE 97%;3-hydroxy-propanoicacidmethylester
CBNumber: CB9703300
Molecular Formula: C4H8O3
Formula Weight: 104.1
MOL File: 6149-41-3.mol

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Methyl 3-hydroxypropanoate Property

Melting point:: 147-148 °C(Solv: benzene (71-43-2); cyclohexane (110-82-7))
Boiling point:: 179°C (estimate)
Density: 1.1050
refractive index: 1.4300
storage temp.: 2-8°C
solubility: Chloroform, Methanol
form: Oil
pka: 13.89±0.10(Predicted)
color: Colourless
InChI: InChI=1S/C4H8O3/c1-7-4(6)2-3-5/h5H,2-3H2,1H3
InChIKey: RVGLEPQPVDUSOJ-UHFFFAOYSA-N
SMILES: C(OC)(=O)CCO

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Safety

HazardClass: IRRITANT
HS Code: 2918199890

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M323488
Product name: Methyl3-hydroxypropanoate
Packaging: 100mg
Price: $50
Updated: 2021/12/16

TRC

Product number: M323488
Product name: Methyl3-hydroxypropanoate
Packaging: 500mg
Price: $75
Updated: 2021/12/16

TRC

Product number: M323488
Product name: Methyl3-hydroxypropanoate
Packaging: 1g
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: W7374
Product name: Methyl3-Hydroxypropanoate
Packaging: 10g
Price: $114
Updated: 2021/12/16

Matrix Scientific

Product number: 063393
Product name: Methyl 3-hydroxypropanoate
Packaging: 10g
Price: $124
Updated: 2021/12/16

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Methyl 3-hydroxypropanoate Chemical Properties,Usage,Production

Uses

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Definition

ChEBI: 2-Methyl-3-hydroxypropanoate is a 3-hydroxy carboxylic acid.

General Description

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyl 3-hydroxypropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 3-hydroxypropanoate Suppliers

China 146 India 3 Japan 1 United States 10 Global 160

Nantong Huakang Medicine Technology Co.,Ltd.

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Shanghai Ennopharm Co., Ltd.

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Shanghai Sphchem Co., Ltd.

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View Lastest Price from Methyl 3-hydroxypropanoate manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Methyl 3-hydroxypropanoate 6149-41-3
Price: US $8.80-2.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-27

Wuhan Konberd Biotech Co., Ltd

Product: Methyl 3-Hydroxypropanoate 6149-41-3
Price: US $1.00-1.00/kg
Min. Order: 1kg
Purity: 0.98+
Supply Ability: 20 tons
Release date: 2025-03-14

Career Henan Chemical Co

Product: METHYL 3-HYDROXYPROPANOATE 6149-41-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-23

6149-41-3, Methyl 3-hydroxypropanoateRelated Search:

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3-hydroxy-propanoicacidmethylester

HOCH2CH2C(O)OCH3

Hydracrylic acid, methyl ester

Methyl beta-hydroxypropionate

Methyl gamma-hydroxypropionate

Methyl hydracrylate

Methyl3-hydroxypropionate

METHYL 3-HYDROXYPROPANOATE

3-Hydroxypropionic acid methyl ester

propanoic acid, 3-hydroxy-, methyl ester

methyl 3-hydroxypropanoate(SALTDATA: FREE)

beta-Hydroxypropionic acid methyl ester

METHYL 3-HYDROXYPROPANOATE 97%

6149-41-3

6419-41-3

ADVANCED INT.