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ALPHA1-ANTICHYMOTRYPSIN, HUMAN

Product Name
ALPHA1-ANTICHYMOTRYPSIN, HUMAN
CAS No.
141176-92-3
Chemical Name
ALPHA1-ANTICHYMOTRYPSIN, HUMAN
Synonyms
ACT;ALPHA-1-X;AACT, HUMAN;ANTI-AACT, HUMAN;ALPHA1-1X, HUMAN;ALPHA1-ACHY, HUMAN;α-Antichymotrypsin;ALPHA-1-X-GLYCOPROTEIN;ALPHA1-ANTICHYMOTRYPSIN;ALPHA-1X-GLYCOPROTEIN, HUMAN
CBNumber
CB9738283
Formula Weight
0
MOL File
Mol file
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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Property

storage temp. 
-20°C
form 
lyophilized powder
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Safety

Hazard Codes 
B
WGK Germany 
3
HS Code 
3504009000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P3360
Product name
Prostate Specific Antigen–α1-Antichymotrypsin Complex human
Purity
≥99%(SDS-PAGE),bufferedaqueoussolution
Packaging
10μg
Price
$741
Updated
2024/03/01
Sigma-Aldrich
Product number
178196
Product name
α₁-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem
Purity
Acute-phase protein present at ~45 mg/100 ml in plasma.
Packaging
100μg
Price
$159
Updated
2024/03/01
Sigma-Aldrich
Product number
A9285
Product name
α1-Antichymotrypsin from human plasma
Purity
≥92.5% (SDS-PAGE), lyophilized powder
Packaging
0.1mg
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
178196
Product name
α?-Antichymotrypsin, Human Plasma
Purity
Acute-phase protein present at ~45 mg/100 ml in plasma.
Packaging
1mg
Price
$877
Updated
2024/03/01
Apolloscientific
Product number
BITP1442
Product name
Human Alpha-1 AntiChymotrypsin
Packaging
20μg
Price
$75
Updated
2021/12/16
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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Chemical Properties,Usage,Production

Uses

α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.

General Description

Kallikrein-3 (KLK3) or prostate specific antigen (PSA) is a serine protease. The protein contains a 371-residue N-terminal heavy chain, which is composed of four Apple domains. The PSA gene is localized to human chromosome 4q35. PSA is synthesized in the liver as a proenzyme known as prekallikrein. It is a key component of the kinin-generating pathways (PK system). The protein is involved in important physiological roles, such as blood pressure modulation, complement activation, and control and maintenance of inflammatory responses. KLK3b alleles are found to be associated with end-stage renal disease (ESRD) suggesting that variants in KLK3 gene might be linked with ESRD susceptibility.
SERPINA3 is also known as α-1-antichymotrypsin (ACT or AACT). The gene consists of five exons and is mapped to human chromosome 14q32.13. The protein contains 423 amino acids and belongs to the family of serpin superfamily of protease inhibitors. SERPINA3 inhibits the activity of pancreatic chymotrypsin, leukocyte, cathepsin G, mast cell chymases, human glandular, kallikrein 2 and kallikrein 3. Elevated expression of the protein has been observed in various types of carcinomas including breast carcinoma, hepatocellular carcinoma, prostate carcinoma and adenocarcinoma of the lung.

Biochem/physiol Actions

α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).

ALPHA1-ANTICHYMOTRYPSIN, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Suppliers

ecochem international chemical broker
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export@ecochem.dk
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Europe
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Sales@kemikalieimport.dk
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Europe
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141176-92-3, ALPHA1-ANTICHYMOTRYPSIN, HUMANRelated Search:


  • A1-ANTICHYMOTRYPSIN FROM HUMAN PLASMA
  • Antichymotrypsin from human plasma
  • α1-antichymotrypsin from human plasma
  • Human Alpha-1 AntiChymotrypsin
  • ANTI-ANTICHYMOTRYPSIN, ALPHA-1-, HUMAN
  • ANTI-AACT, HUMAN
  • ANTICHYMOTRYPSIN, ALPHA-1, HUMAN
  • AACT, HUMAN
  • ACT
  • ALPHA-1-X
  • ALPHA-1-X-GLYCOPROTEIN
  • ALPHA-1X-GLYCOPROTEIN, HUMAN
  • ALPHA1-ANTICHYMOTRYPSIN
  • ALPHA1-ANTICHYMOTRYPSIN, HUMAN
  • ALPHA1-ANTICHYMOTRYPSIN, HUMAN PLASMA
  • ALPHA-1 ANTICHYMOTRYPSIN PLASMA
  • ALPHA1-ACHY, HUMAN
  • ALPHA1-1X-GLYCOPROTEIN, HUMAN
  • ALPHA1-1X, HUMAN
  • α?-Antichymotrypsin, Human Plasma
  • α-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem
  • α-Antichymotrypsin
  • α1-Antichymotrypsin, from human plasma
  • 141176-92-3
  • Biochemicals and Reagents
  • BioChemical
  • Cathepsin G
  • A to C
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • proteins