Detected method
ChemicalBook > CAS DataBase List > D(+)-Phenylalaninol

D(+)-Phenylalaninol

Detected method
Product Name
D(+)-Phenylalaninol
CAS No.
5267-64-1
Chemical Name
D(+)-Phenylalaninol
Synonyms
D-PHENYLALANINOL;H-D-PHE-OL;D-Phenylalanino;(R)-2-AMINO-3-PHENYL-1-PROPANOL;(2R)-2-amino-3-phenylpropan-1-ol;(R)-2-AMINO-3-PHENYL-PROPAN-1-OL;H-D-Phen-ol;R-228060-001;D-PHENYLANINOL;D-PHEYLALANINOL
CBNumber
CB9741308
Molecular Formula
C9H13NO
Formula Weight
151.21
MOL File
5267-64-1.mol
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D(+)-Phenylalaninol Property

Melting point:
93-95 °C(lit.)
Boiling point:
122 °C / 4mmHg
alpha 
23 º (c=1.2, 1 N HCl 22 ºC)
Density 
1.0406 (rough estimate)
refractive index 
23.5 ° (C=1.2, 1mol/L HCl)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in Dichloromethane, Ethyl Acetate, Methanol.
form 
Crystalline Powder and Chunks
pka
12.85±0.10(Predicted)
color 
White to yellow
optical activity
[α]/D +22.8°, c = 1.2 in 1 M HCl
Sensitive 
Air Sensitive
BRN 
4665408
InChI
InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3
InChIKey
STVVMTBJNDTZBF-DJEYLCQNNA-N
SMILES
C(C1C=CC=CC=1)[C@@H](N)CO |&1:7,r|
CAS DataBase Reference
5267-64-1(CAS DataBase Reference)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3259 8/PG 3
WGK Germany 
3
10-23
HazardClass 
IRRITANT
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
284491
Product name
(R)-(+)-2-Amino-3-phenyl-1-propanol
Purity
98%
Packaging
5g
Price
$142
Updated
2023/01/07
TCI Chemical
Product number
P1289
Product name
D-Phenylalaninol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$72
Updated
2024/03/01
TCI Chemical
Product number
P1289
Product name
D-Phenylalaninol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$218
Updated
2024/03/01
Alfa Aesar
Product number
L09697
Product name
D-Phenylalaninol, 98%
Packaging
1g
Price
$40.65
Updated
2024/03/01
Usbiological
Product number
019430
Product name
D-Phenylalaninol
Packaging
5g
Price
$403
Updated
2021/12/16
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D(+)-Phenylalaninol Chemical Properties,Usage,Production

Detected method

Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.

Description

D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution.

Chemical Properties

white to light yellow crystal powde

Uses

D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.

Purification Methods

It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]

D(+)-Phenylalaninol Preparation Products And Raw materials

Raw materials

Preparation Products

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D(+)-Phenylalaninol Suppliers

Hunan Caiya Biological Technology Co., Ltd
Tel
15580017485
Email
2036676503@qq.com
Country
China
ProdList
91
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
13851620508 13851620508
Fax
86-025-58905816
Email
shirly@redwood.com.cn
Country
China
ProdList
218
Advantage
60
Hubei Hengluyuan Technology co.ltd
Tel
027-88188016 18717196322
Email
1764683941@qq.com
Country
China
ProdList
5748
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
430
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from D(+)-Phenylalaninol manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
d-phe-ol 5267-64-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-01-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D(+)-Phenylalaninol 5267-64-1
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-08-28
Hebei Chuanghai Biotechnology Co,.LTD
Product
D(+)-Phenylalaninol 5267-64-1
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23

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