D(+)-Phenylalaninol

Detected method

Product Name: D(+)-Phenylalaninol
CAS No.: 5267-64-1
Chemical Name: D(+)-Phenylalaninol
Synonyms: D-PHENYLALANINOL;H-D-PHE-OL;D-Phenylalanino;(R)-2-AMINO-3-PHENYL-1-PROPANOL;(2R)-2-amino-3-phenylpropan-1-ol;(R)-2-AMINO-3-PHENYL-PROPAN-1-OL;H-D-Phen-ol;R-228060-001;D-PHENYLANINOL;D-PHEYLALANINOL
CBNumber: CB9741308
Molecular Formula: C9H13NO
Formula Weight: 151.21
MOL File: 5267-64-1.mol

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D(+)-Phenylalaninol Property

Melting point:: 93-95 °C(lit.)
Boiling point:: 122 °C / 4mmHg
alpha: 23 º (c=1.2, 1 N HCl 22 ºC)
Density: 1.0406 (rough estimate)
refractive index: 23.5 ° (C=1.2, 1mol/L HCl)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in Dichloromethane, Ethyl Acetate, Methanol.
form: Crystalline Powder and Chunks
pka: 12.85±0.10(Predicted)
color: White to yellow
optical activity: [α]/D +22.8°, c = 1.2 in 1 M HCl
Sensitive: Air Sensitive
BRN: 4665408
InChI: InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3
InChIKey: STVVMTBJNDTZBF-DJEYLCQNNA-N
SMILES: C(C1C=CC=CC=1)[C@@H](N)CO |&1:7,r|
CAS DataBase Reference: 5267-64-1(CAS DataBase Reference)

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Safety

Hazard Codes: C,Xi
Risk Statements: 34
Safety Statements: 26-36/37/39-45-27
RIDADR: UN 3259 8/PG 3
WGK Germany: 3
F: 10-23
HazardClass: IRRITANT
HazardClass: 8
PackingGroup: III
HS Code: 29221990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 284491
Product name: (R)-(+)-2-Amino-3-phenyl-1-propanol
Purity: 98%
Packaging: 5g
Price: $142
Updated: 2023/01/07

TCI Chemical

Product number: P1289
Product name: D-Phenylalaninol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $72
Updated: 2024/03/01

TCI Chemical

Product number: P1289
Product name: D-Phenylalaninol
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $218
Updated: 2024/03/01

Alfa Aesar

Product number: L09697
Product name: D-Phenylalaninol, 98%
Packaging: 1g
Price: $40.65
Updated: 2024/03/01

Usbiological

Product number: 019430
Product name: D-Phenylalaninol
Packaging: 5g
Price: $403
Updated: 2021/12/16

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D(+)-Phenylalaninol Chemical Properties,Usage,Production

Detected method

Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.

Description

D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution.

Chemical Properties

white to light yellow crystal powde

Uses

D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.

Purification Methods

It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]

D(+)-Phenylalaninol Preparation Products And Raw materials

Raw materials

Preparation Products

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D(+)-Phenylalaninol Suppliers

Americas 1 Austria 1 Belgium 3 Canada 3 China 362 Europe 6 France 2 Germany 10 India 24 Italy 1 Japan 7 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 67 Global 515

Hunan Caiya Biological Technology Co., Ltd

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INTATRADE GmbH

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ITIC MEDCHEM(SUZHOU) CO.,LTD.

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Alfa Aesar

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View Lastest Price from D(+)-Phenylalaninol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: D(+)-Phenylalaninol 5267-64-1
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-08-28

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: d-phe-ol 5267-64-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-01-20

Hebei Chuanghai Biotechnology Co,.LTD

Product: D(+)-Phenylalaninol 5267-64-1
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-23

5267-64-1, D(+)-PhenylalaninolRelated Search:

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(R)-2-AMINO-3-PHENYL-PROPAN-1-OL

(R)-(+)-PHENYLALANINOL

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PHENYLALANINOL-D

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D(+)-Phenylalaninol USP/EP/BP

D-(+)-2-Amino-3-phenyl-1-proanol

(+)-D-Phenylalaninol

(2S)-2-amino-1-phenylpropan-1-ol

5267-64-1

15267-64-1

Amino Alcohols (Chiral)

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Asymmetric Synthesis

Amino Acid Derivatives