Description References
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L-tert-Leucine

Description References
Product Name
L-tert-Leucine
CAS No.
20859-02-3
Chemical Name
L-tert-Leucine
Synonyms
LEUCINE;LEU;H-LEU-OH;Tle;L-tertiary leucine;H-L-LEU-OH;L-Tle-OH;L-tert-Leu-OH;L-A-AMINOISOCAPROIC ACID;(S)-2-Amino-3,3-dimethylbutanoicacid
CBNumber
CB9853319
Molecular Formula
C6H13NO2
Formula Weight
131.17
MOL File
20859-02-3.mol
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L-tert-Leucine Property

Melting point:
≥300 °C (lit.)
alpha 
6.3 º (c=4, 6 N HCl 200 ºC)
Boiling point:
217.7±23.0 °C(Predicted)
Density 
1.1720 (estimate)
refractive index 
-9 ° (C=3, H2O)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
1 M HCl: 50 mg/mL
form 
powder
pka
2.39±0.12(Predicted)
color 
White to almost white
optical activity
[α]20/D 9.5°, c = 3 in H2O
Water Solubility 
125.5 g/L (20 ºC)
BRN 
1721824
InChIKey
NPDBDJFLKKQMCM-SCSAIBSYSA-N
CAS DataBase Reference
20859-02-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
OH2850000
Hazard Note 
Irritant
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
269107
Product name
L-tert-Leucine
Purity
99%
Packaging
5g
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
269107
Product name
L-tert-Leucine
Purity
99%
Packaging
25g
Price
$183
Updated
2024/03/01
TCI Chemical
Product number
L0147
Product name
L-tert-Leucine
Purity
>98.0%(T)
Packaging
1g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
L0147
Product name
L-tert-Leucine
Purity
>98.0%(T)
Packaging
5g
Price
$48
Updated
2024/03/01
Alfa Aesar
Product number
L13707
Product name
L-tert-Leucine, 99%
Packaging
1g
Price
$46.65
Updated
2024/03/01
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L-tert-Leucine Chemical Properties,Usage,Production

Description

L-tert-Leucine is an essential amino acid making up one third of our muscle protein. L-tert-leucine is important in developing chiral pharmaceutically active chemicals. It can be used as a food additive. It is used in the formation of sterols. It can also be used as the catalyst in the production of cobalt oxazoline palladacycles complex. It can also be used for the production of Chiral tridentate Schiff base ligands.

References

Korkmaz, Neslihan, D. Astley, and S. T. Astley. "Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction." Turkish Journal of Chemistry 35.3(2011):1-17.
https://www.alfa.com/en/catalog/L13707/
http://igem.org/abstract_pdf_file.cgi?id=1719

Chemical Properties

White to almost white powder

Uses

L-tert-Leucine is an essential amino acid and makes up one third of our muscle protein. It can be used as a food additive. It is used in the formation of sterols. It is used in the production of cobalt oxazoline palladacycles complex, which acts as a catalyst in the rearrangement of prochiral N-aryl trifluoroacetimidates to allylic amides yielded in significantly higher enantioselectivities with the (S)-(pR)-diasteroisomer.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 523, 1955
Tetrahedron Letters, 19, p. 4625, 1978 DOI: 10.1016/S0040-4039(01)85688-4

L-tert-Leucine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-tert-Leucine manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
L-tert-Leucine 20859-02-3
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98% HPLC
Supply Ability
1000KG
Release date
2023-01-03
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
L-Tle 20859-02-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T+
Release date
2023-09-25
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
L-tert-Leucine 20859-02-3
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99
Supply Ability
20tons
Release date
2024-02-06

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