Propargyl-PEG3-Ms Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Liquid

color 

Colorless to light yellow

Propargyl-PEG3-Ms Usage And Synthesis

Description

Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.

Uses

Propargyl-PEG2-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Bai S, et al. Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. J Med Chem. 2014 May 22;57(10):4239-51. DOI:10.1021/jm5001453

Propargyl-PEG3-Ms(943726-01-0)Related Product Information

• Propargyl-PEG3-methyl ester
• Propargyl-PEG3-Sulfone-PEG3-Propargyl
• Propargyl-PEG3-phosphonic acid ethyl ester
• Propargyl-PEG3-Bromide
• Propargyl--PEG3-phosphonic acid
• Propargyl-PEG4-5-nitrophenyl carbonate
• Propargyl-PEG3-t-butyl ester
• Propargyl-PEG3-NH2
• Propargyl-PEG4-(CH2)3-acid
• Propargyl-PEG4-(CH2)3-methyl ester