5-Bromo-2-fluoropyridine Chemical Properties

Boiling point:

162-164 °C750 mm Hg(lit.)

Density 

1.71 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.5325(lit.)

Flash point:

165 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

-2.79±0.10(Predicted)

form 

Liquid

color 

Clear colorless yellow

Specific Gravity

1.710

BRN 

1363171

InChIKey

MYUQKYGWKHTRPG-UHFFFAOYSA-N

CAS DataBase Reference

766-11-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36/37-37/39

RIDADR 

UN2810

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29339900

MSDS

• Language:English Provider:5-Bromo-2-fluoropyridine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Bromo-2-fluoropyridine Usage And Synthesis

Description

5-Bromo-2-fluoropyridine is a halogenated pyridine that has been used as a molecular scaffold for many Active Pharmaceutical Ingredients (APIs) such as Neuropeptide Y Receptor Y5 Inhibitors, SARS-CoV-2 Major Protease Inhibitors, and Indoleamine-2,3-Dioxygenase-1 Inhibitors in cancer immunotherapy. 5-Bromo-2-fluoropyridine is also an ideal building block for semiconductors, due to its aromaticity and electron deficiency. A host material of 5-(5-(2,4,6-triiso-propylphenyl)pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole is synthesized from 5-bromo-2-fluoropyridine for OLED applications.

Chemical Properties

5-Bromo-2-fluoropyridine is a colourless or yellowish liquid compound with a density of 1.71 g/cm3 at 25° C; boiling point of 162-164° C (lit.) at 750 mmHg; stored at room temperature.

Uses

5-Bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. Also used in the synthesis of benzofurano[3,2-d]pyrimidin-2-one derived inhbitors.

5-Bromo-2-fluoropyridine(766-11-0)Related Product Information

• 2-Fluoropyridine
• 1-Hexadecylpyridinium bromide
• 3-Bromoanisole
• 2,6-Lutidine
• Ethyl bromodifluoroacetate
• 4-Bromobenzotrifluoride
• 4-BROMO-2-FLUOROPYRIDINE 97%,4-BROMO-2-FLUOROPYRIDINE
• 2-Fluoro-6-methylpyridine
• 5-Chloro-2-fluoropyridine
• 2-Fluoropyridine-6-carboxylic acid
• 2-Fluoro-3-nitropyridine
• 5-Bromo-2-fluoro-4-methyl-pyridine
• 5-Chloro-2-fluoro-3-methylpyridine
• 2-CHLORO-6-FLUOROPYRIDINE
• 3-Bromo-2-fluoro-5-methylpyridine
• 2-Fluoro-3-methylpyridine
• 3-Amino-2-fluoropyridine
• 3-Chloro-2-fluoro-pyridine