Lercanidipine hydrochloride
Lercanidipine hydrochloride Basic information
- Product Name:
- Lercanidipine hydrochloride
- Synonyms:
-
- 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride
- LERCANIDIPINE HCL
- LERCANIDIPINE HYDROCHLORIDE
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylicAcid2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimeth
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
- 3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl] 5-Methyl ester,hydrochloride (1:1)
- Lercanidipine Impurity 1
- CAS:
- 132866-11-6
- MF:
- C36H42ClN3O6
- MW:
- 648.19
- EINECS:
- 603-682-3
- Product Categories:
-
- API
- Cardiovascular APIs
- Miscellaneous Natural Products
- Aromatics
- Dihydropyridine
- Heterocycles
- Dihydropyridine Class Chemicals
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Calcium Channel Modulators
- Inhibitors and Activators
- Voltage-gated Ion Channels
- Mol File:
- 132866-11-6.mol
Lercanidipine hydrochloride Chemical Properties
- Melting point:
- 175-177°C
- storage temp.
- 2-8°C
- solubility
- soluble in Methanol
- form
- powder
- color
- yellow
- Merck
- 14,5446
- InChIKey
- WMFYOYKPJLRMJI-UHFFFAOYSA-N
- CAS DataBase Reference
- 132866-11-6(CAS DataBase Reference)
Lercanidipine hydrochloride Usage And Synthesis
Chemical Properties
Pale-Yellow Powder
Uses
long-acting dihydropyridine calcium channel blocker, antihypertensive
Uses
A dihydropyridine calcium channel blocker. Antihypertensive.
Definition
ChEBI: Lercanidipine hydrochloride is a diarylmethane.
brand name
Cardiovasc (Recor dati, Italy); Carmen (Recordati, Italy); Corifeo (Recordati, Italy); Lercadip (Recordati, Italy); Lercan (Recordati, Italy); Lercapin (Recordati, Italy); Lercaton (Recordati, Italy); Lerkamen (Recordati, Italy); Lerzam (Recordati, Italy); Renovia (Recordati, Italy); Vasodip (Recordati, Italy); Zandip (Recordati, Italy); Zanicor (Recordati, Italy).
Biological Activity
L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.
Biochem/physiol Actions
Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.
Lercanidipine hydrochlorideSupplier
- Tel
- 19556085883
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- 821-50328103-801 18930552037
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- 400-0066400 13621662912
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- 021-20908456
- sales@BioChemBest.com
Lercanidipine hydrochloride(132866-11-6)Related Product Information
- Dimethyl carbonate
- Lercanidipine
- Quinolinic acid
- Dimethyl phthalate
- ETHANE
- Dacthal
- 2,6-Lutidine
- 2,5-PYRIDINEDICARBOXYLIC ACID
- Dimethyl fumarate
- Dimethyl disulfide
- N,N-Dimethylallylamine
- Topotecan hydrochloride
- 2,5-Dimethylpyridine
- Chromium picolinate
- Dimethyl sulfate
- DIMETHYLAMINOPYRIDINE, POLYMER-BOUND
- Dimethyl sulfoxide
- 1-AdaMantanethylaMine