Basic information Safety Supplier Related

H2N-PEG11-CH2CH2COOH

Basic information Safety Supplier Related

H2N-PEG11-CH2CH2COOH Basic information

Product Name:
H2N-PEG11-CH2CH2COOH
Synonyms:
  • H2N-PEG11-CH2CH2COOH
  • Amino-PEG11-propionic acid
  • Amino-PEG11-COOH
  • Amino-PEG11-acid
  • H2N-PEG11-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34-Undecaoxahexatriacontanoic acid, 36 amino-
  • 4,7,10,13,16,19,22,25,28,31,34-Undecaoxahexatriacontanoic acid, 36 amino-
CAS:
1616426-12-0
MF:
C25H51NO13
MW:
573.67
Mol File:
1616426-12-0.mol
More
Less

H2N-PEG11-CH2CH2COOH Chemical Properties

Boiling point:
637.6±55.0 °C(Predicted)
Density 
1.125±0.06 g/cm3(Predicted)
pka
4.28±0.10(Predicted)
More
Less

H2N-PEG11-CH2CH2COOH Usage And Synthesis

Biological Activity

Amino-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

H2N-PEG11-CH2CH2COOHSupplier

T&W GROUP
Tel
021-61551611 13296011611
Email
contact@trustwe.com
Zhengzhou Huiju Chemical Co., Ltd.
Tel
0371-55900031 18137872243
Email
2853979815@qq.com
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Email
info@amateksci.com
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com