m-PEG5-Ms
m-PEG5-Ms Basic information
- Product Name:
- m-PEG5-Ms
- Synonyms:
-
- m-PEG5-Ms
- 2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate
- 2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
- PEG4-Oms
- m-PEG4-OMs
- CAS:
- 130955-37-2
- MF:
- C10H22O7S
- MW:
- 286.34
- Mol File:
- 130955-37-2.mol
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m-PEG5-Ms Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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m-PEG5-Ms Usage And Synthesis
Description
m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).
target
| Cleavable
| PEGs
|