Basic information Safety Supplier Related

Proparyl-PEG5-methane

Basic information Safety Supplier Related

Proparyl-PEG5-methane Basic information

Product Name:
Proparyl-PEG5-methane
Synonyms:
  • m-PEG5-Propargyl
  • ROPARGYL-PEG5-METHANE
  • Proparyl-PEG5-methane
  • 2,5,8,11,14-Pentaoxaheptadec-16-yne
  • mPEG4-Alkyne
  • PROPARYL-PEG4-ME
  • Propargyl-PEG5-methane
  • mPEG4-Propyne
CAS:
1101668-39-6
MF:
C12H22O5
MW:
246.3
Product Categories:
  • peg
Mol File:
1101668-39-6.mol
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Proparyl-PEG5-methane Chemical Properties

Boiling point:
304.2±32.0 °C(Predicted)
Density 
1.016±0.06 g/cm3(Predicted)
storage temp. 
Store at Room Tem.
form 
clear liquid
color 
Colorless to Light yellow
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Safety Information

HS Code 
2909.19.1800
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Proparyl-PEG5-methane Usage And Synthesis

Description

Propargyl-PEG5-methane has a propargyl group which can react with azide compounds via copper catalyzed Click Chemistry reactions. The PEG units increase water-solubility of the molecule.

Uses

m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74

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