METHANTHELINE BROMIDE
METHANTHELINE BROMIDE Basic information
- Product Name:
- METHANTHELINE BROMIDE
- Synonyms:
-
- ammonium,diethyl(2-hydroxyethyl)methyl-,bromide,xanthene-9-carboxylate
- asabaine
- METHANETHELINIUMBROMIDE
- Bantosal
- frenogastrico
- gastrosedan
- mantheline
- metantyl
- CAS:
- 53-46-3
- MF:
- CH3-
- MW:
- 15.03452
- EINECS:
- 2001760
- Mol File:
- 53-46-3.mol
METHANTHELINE BROMIDE Chemical Properties
- Melting point:
- 175-176°
- Density
- 1.3380 (rough estimate)
- refractive index
- 1.6200 (estimate)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Dark Orange to Very Dark Orange
METHANTHELINE BROMIDE Usage And Synthesis
Uses
Ulcine is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.
Uses
METHANTHELINE BROMIDE is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.
Definition
ChEBI: Methantheline bromide is a member of xanthenes.
General Description
Methanthelinebromide, diethyl(2-hydroxyethyl)methylammonium bromidexanthene-9-carboxylate (Banthine Bromide), is awhite, slightly hygroscopic, crystalline salt that is solublein water to produce solutions with a pH of about 5.Aqueous solutions are not stable and hydrolyze in a fewdays. The bromide form is preferable to the very hygroscopicchloride.
Among the conditions for which methantheline bromideis indicated are gastritis, intestinal hypermotility, bladderirritability, cholinergic spasm, pancreatitis, hyperhidrosis,and peptic ulcer, all of which are manifestations ofparasympathotonia.
Clinical Use
Methantheline bromide, introduced in 1950, is a potent anticholinergicagent and acts at the nicotinic cholinergic receptors of thesympathetic and parasympathetic systems, as well as at themyoneural junction of the postganglionic cholinergic fibers.Like other quaternary ammonium drugs, methantheline bromideis absorbed incompletely from the GI tract.
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METHANTHELINE BROMIDE(53-46-3)Related Product Information
- (2-HYDROXY-PHENYL)-ACETIC ACID METHYL ESTER
- ETHYL 2-PHENYLPROPIONATE
- Triethylmethylammonium bromide
- 2-Propylpiperidine
- Adiphenine hydrochloride
- TRIETHYLAMINE HYDROBROMIDE
- 2,2-Diphenylacetic acid
- METHYL 9H-XANTHENE-9-CARBOXYLATE
- 2-METHOXYPHENYLACETIC ACID METHYL ESTER
- Propantheline bromide
- ACETYLCHOLINE BROMIDE
- CHOLINE BROMIDE
- METHANTHELINE BROMIDE
- XANTHENE-9-CARBOXYLIC ACID
- Ethyl 9H-xanthene-9-carboxylate
- METHYL DIPHENYLACETATE
- 2-Hydroxyphenylacetic acid
- DIPHENYL-ACETIC ACID ETHYL ESTER