2,2-Diphenylacetic acid Chemical Properties

Melting point:

147-149 °C(lit.)

Boiling point:

195°C 25mm

Density 

1,257 g/cm³

vapor pressure 

0.001Pa at 25℃

refractive index 

1.6000 (estimate)

Flash point:

195°C/25mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

0.13g/l

form 

Crystalline Powder

pka

3.94(at 25℃)

color 

White to creamy-white

PH

3.8 (H2O, 20℃)(saturated solution)

Water Solubility 

Slightly soluble in water(0.13g/L).

Merck 

14,3316

BRN 

1910978

InChIKey

PYHXGXCGESYPCW-UHFFFAOYSA-N

LogP

3.17 at 25℃

CAS DataBase Reference

117-34-0(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetic acid, «alpha»-phenyl-(117-34-0)

EPA Substance Registry System

Benzeneacetic acid, .alpha.-phenyl- (117-34-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/38-36/37/38

Safety Statements 

24/25-36/37-26

WGK Germany 

2

RTECS 

AH2515000

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29163900

Toxicity

mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Farmaco, Edizione Scientifica. Vol. 13, Pg. 286, 1958.

MSDS

• Language:English Provider:2,2-Diphenylacetic acid
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2,2-Diphenylacetic acid Usage And Synthesis

Chemical Properties

white to creamy-white crystalline powder

Uses

Kinetic resolution of racemic 1-heteroarylalkanols by asymmetric esterification using diphenylacetic acid with pivalic anhydride and a chiral acyl-transfer catalyst is described. Molecular crystal of acridine and diphenylacetic acid and its absolute asymmetric photodecarboxylating condensation generates chirality in a two-component. The activation parameters for the racemization of a series of ortho-alkyl-substituted diphenylacetic acids are determined.

Definition

ChEBI: A monocarboxylic acid that is acetic acid where the methyl hydrogens have been replaced by two phenyl groups respectively.

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2325, 1947 DOI: 10.1021/ja01202a023
Synthetic Communications, 17, p. 1919, 1987 DOI: 10.1080/00397918708057804

Purification Methods

Crystallise the acid from *benzene, H2O or aqueous 50% EtOH. [Beilstein 9 H 673, 9 IV 2492.]

2,2-Diphenylacetic acid(117-34-0)Related Product Information

• Phenylacetic acid
• Phenyl sulfoxide
• 2-Phenylacetophenone
• Triphenylacetic acid
• 2,2-Diphenylglycine
• Propantheline bromide
• 2,2'-DICHLOROBENZILIC ACID
• Adiphenine hydrochloride
• Benzilic acid
• 9-Carboxyfluorene
• Methyl benzilate
• METHANTHELINE BROMIDE
• XANTHENE-9-CARBOXYLIC ACID
• METHYL DIPHENYLACETATE
• BENACTYZINE HYDROCHLORIDE
• ETHYL BENZILATE
• BIS(2,4-DINITROPHENYL)ACETIC ACID ETHYL ESTER
• 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID