2,4-Difluoronitrobenzene Chemical Properties

Melting point:

9-10 °C (lit.)

Boiling point:

203-204 °C (lit.)

Density 

1.451 g/mL at 25 °C (lit.)

vapor density 

>1 (vs air)

refractive index 

n20/D 1.511(lit.)

Flash point:

195 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

color 

Light yellow to Brown

Specific Gravity

1.45

Water Solubility 

Insoluble in water.

BRN 

2048034

Stability:

Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.

InChIKey

RJXOVESYJFXCGI-UHFFFAOYSA-N

CAS DataBase Reference

446-35-5(CAS DataBase Reference)

NIST Chemistry Reference

2,4-Difluoronitrobenzene(446-35-5)

EPA Substance Registry System

2,4-Difluoronitrobenzene (446-35-5)

Safety Information

Hazard Codes 

T,Xi,Xn

Risk Statements 

25-36/37/38-23/24/25-20/21/22

Safety Statements 

26-45-36/37/39-23

RIDADR 

UN 2810 6.1/PG 1

WGK Germany 

3

RTECS 

CZ5730000

Hazard Note 

Irritant

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29049090

MSDS

• Language:English Provider:2,4-Difluoronitrobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4-Difluoronitrobenzene Usage And Synthesis

Synthesis

KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF.

Chemical Properties

yellow liquid

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles.
2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents.

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction, (±)-horsfiline and resin-bound-2-arylaminobenzimidazoles.

Uses

2,4-Difluoronitrobenzene has been used in the synthesis of:

• 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction
• (±)-horsfiline
• resin-bound 2-arylaminobenzimidazoles

General Description

Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.

2,4-Difluoronitrobenzene(446-35-5)Related Product Information

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