2,4-Difluoroaniline Chemical Properties

Melting point:

-7.5 °C (lit.)

Boiling point:

170 °C/753 mmHg (lit.)

Density 

1.268 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.506(lit.)

Flash point:

145 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

Not miscible or difficult to mix.

form 

Liquid

pka

3.26±0.10(Predicted)

Specific Gravity

1.284 (20/4℃)

color 

Clear brown

Water Solubility 

1-5 g/100 mL at 20.55 ºC

Merck 

14,3147

BRN 

2802556

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.

LogP

1.7 at 25℃ and pH5-9

CAS DataBase Reference

367-25-9(CAS DataBase Reference)

NIST Chemistry Reference

2,4-Difluoroaniline(367-25-9)

EPA Substance Registry System

2,4-Difluoroaniline (367-25-9)

Safety Information

Hazard Codes 

Xn,T,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

28-36/37/39-26-36

RIDADR 

UN 2941 6.1/PG 3

WGK Germany 

1

RTECS 

BX3680000

F 

8-9-23

Hazard Note 

Toxic

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29214210

MSDS

• Language:English Provider:1-Amino-2,4-difluorobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4-Difluoroaniline Usage And Synthesis

Description

2,4-difluoroaniline is an important intermediate used in organic synthesis, pharmaceuticals agrochemicals, dyes, and agricultural chemicals.

Reference

R. Garth Pews, J. A. Gall, Process and intermediates for the preparation of 2,6-difluoroaniline, Paten US5041674A

Chemical Properties

dark red liquid

Uses

2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

General Description

Dark reddish-purple liquid.

Air & Water Reactions

2,4-Difluoroaniline may be sensitive to prolonged exposure to air. . Water soluble.

Reactivity Profile

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: 2,4-Difluoroaniline may be irritating to tissues.

Fire Hazard

2,4-Difluoroaniline is combustible.

2,4-Difluoroaniline(367-25-9)Related Product Information

• ALTRENOGEST
• 3,5-Difluoroaniline
• 2-Fluoroaniline
• 4-Fluoroaniline
• 3-Fluoroaniline
• Glycine
• Diphenylamine
• 1,3-Difluorobenzene
• 3-Aminobenzotrifluoride
• 2,4-Difluoronitrobenzene
• Sodium diphenylamine-4-sulfonate
• N,N-Dimethyl-1,4-phenylenediamine
• 4-(Trifluoromethoxy)aniline
• N,N-Dimethylaniline
• 1,2-Difluorobenzene
• Betaine
• Aniline
• flurbiprofen