SR27897
SR27897 Basic information
- Product Name:
- SR27897
- Synonyms:
-
- SR27897
- 2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-aceticacid
- 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate
- SR 27897 hydrate
- 1H-Indole-1-acetic acid,2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-
- {2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid
- 2-(2-((4-(2-Chlorophenyl)thiazol-2-yl)carbamoyl)-1H-indol-1-yl)acetic acid
- CAS:
- 136381-85-6
- MF:
- C20H14ClN3O3S
- MW:
- 411.86
- Mol File:
- 136381-85-6.mol
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SR27897 Chemical Properties
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at +4°C
- solubility
- DMSO: ≥10mg/mL at warmed to 60°C
- pka
- 4.00±0.10(Predicted)
- form
- powder
- color
- white to tan
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SR27897 Usage And Synthesis
Uses
SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist.
Definition
ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid.
Biological Activity
Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo .
storage
Store at +4°C
SR27897Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
- Tel
- 13761635123
- 1014988033@qq.com
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