Tussilagone
Tussilagone Basic information
- Product Name:
- Tussilagone
- Synonyms:
-
- Tussilagone
- L 652469
- Tussilagone, 98%, from Farfarae Flos
- 2-Pentenoic acid, 3-methyl-, (1S,3aR,5R,7S,7aS)-1-[(1R)-1-(acetyloxy)ethyl]octahydro-4-methylene-7-(1-methylethyl)-2-oxo-1H-inden-5-yl ester, (2E)-
- (1R,3aR,5R,7S,7aS)-1-(1-acetyloxyethyl)-4-methylidene-2-oxo-7-propan-2-yl-3,3a,5,6,7,7a-hexahydro-1H-inden-5-yl](E)-3-methylpent-2-enoate
- (1S,3aR,5R,7S,7aS)-1-((R)-1-Acetoxyethyl)-7-isopropyl-4-methylene-2-oxooctahydro-1H-inden-5-yl (E)-3-methylpent-2-enoate
- CAS:
- 104012-37-5
- MF:
- C23H34O5
- MW:
- 390.51
- Mol File:
- 104012-37-5.mol
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Tussilagone Chemical Properties
- Boiling point:
- 471.3±35.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3 (20 ºC 760 Torr)
- form
- Solid
- color
- White to off-white
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Safety Information
- Safety Statements
- 24/25
- HS Code
- 29389090
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Tussilagone Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in ether, chloroform, ethyl acetate, methanol, insoluble in water, derived from the flower bud of Asteraceae Tussilago farfara, Senecio kleinia Less root.
Biological Activity
Tussilagone, the main active ingredient of Tussilago farfara, has anti-inflammatory properties. It ameliorates the inflammatory response of dextran sulfate sodium-induced colitis in mice.
in vivo
Tussilagone administration (1 mg/kg and 10 mg/kg) produced decreased mortality and lung injury in CLP-activated septic mice. Augmented expression of cyclooxygenase (COX)-2 and TNF-α in pulmonary alveolar macrophages of septic mice were attenuated by tussilagone administration.
TussilagoneSupplier
Chengdu Peter-like Biotechnology Co., Ltd. Gold
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- 028-81700200 18108052721
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BioBioPha Co., Ltd.
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- 0871-65217109 13211707573;
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ShangHai YuanYe Biotechnology Co., Ltd.
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- 021-61312847 13636370518
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Chengdu Biopurify Phytochemicals Ltd.
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- +86-028-82633397 18982077548
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Shanghai Winherb Medical Technology Co., Ltd.
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- 400-400-186-5138 13341702378
- winherb@126.com