evocarpine Chemical Properties

Melting point:

34-38℃

Boiling point:

456.2±45.0 °C(Predicted)

Density 

0.975±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

2-8°C

form 

Solid

pka

2.52±0.70(Predicted)

color 

White to off-white

CAS DataBase Reference

15266-38-3

evocarpine Usage And Synthesis

Uses

Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity[1][2].

Definition

ChEBI: Evocarpine is a member of quinolines.

References

[1] J Yamahar, et al. The vasorelaxant effect of evocarpine in isolated aortic strips: mode of action. Eur J Pharmacol. 1988 Oct 11;155(1-2):139-43. DOI:10.1016/0014-2999(88)90411-6
[2] C Hochfellner, et al. Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. J Appl Microbiol. 2015 Apr;118(4):864-72. DOI:10.1111/jam.12753
[3] N Y Kim, et al. Cyclic adenosine monophosphate inhibits quinolone alkaloid evocarpine-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells. Pharmacol Toxicol. 2000 Jul;87(1):1-5. DOI:10.1111/j.0901-9928.2000.870101.x

evocarpine(15266-38-3)Related Product Information

• FMOC-ASN(TRT)-OPFP
• Apigenin 7-glucoside
• D-Mannitol
• 3',5-Dihydroxy-7-(β-D-glucopyranosyloxy)-4'-methoxyflavone
• Raubasine
• KAEMPFEROL-3-O-RUTINOSIDE
• Tetrahydroberberine
• Angoroside C
• Huperzine B
• SANTALOL
• ALLOCRYPTOPINE
• L-Aspartic acid
• L-Theanine
• Hematoxylin
• Sodium ferulic
• Oxalic acid
• Rutaecarpine
• Evodiamine