ChemicalBook > Product Catalog > Biochemical Engineering > Chinese Herbs > 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Basic information
- Product Name:
- 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
- Synonyms:
-
- 2-Acetyl-3-methyl-1,8-naphthalenediol
- Musizin
- Nepodin
- Musizine
- NSC 365795
- NEPODIN (MUSIZIN)
- Ethanone,1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-
- 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone USP/EP/BP
- CAS:
- 3785-24-8
- MF:
- C13H12O3
- MW:
- 216.23
- Product Categories:
-
- Miscellaneous Natural Products
- Mol File:
- 3785-24-8.mol
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1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Chemical Properties
- Melting point:
- 165-166℃ (methanol )
- Boiling point:
- 357.9±22.0 °C(Predicted)
- Density
- 1.285±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- 4°C, protect from light
- solubility
- Methanol: soluble
- form
- A solid
- pka
- 5.13±0.50(Predicted)
- color
- White to yellow
- InChI
- InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3
- InChIKey
- DMLHPCALHMPJHS-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=C(C)C=C2C(=C1O)C(O)=CC=C2)C
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1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Usage And Synthesis
Chemical Properties
Pale yellow crystals, soluble in methanol, ethanol, ethyl acetate, insoluble in water, derived from the root of the Polygonaceae plant Rhizoma Cibotii or Rhizoma Nepalensis.
Uses
1-(1,8-Dihydroxy-3-methyl-naphthalen-2-yl)-ethanone is a naphthalene for proteomics research.
Definition
ChEBI: Nepodin is a member of naphthols.
in vivo
Nepodin (Musizin) (orally administration; 2-10 mg/kg; 4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner[2].
| Animal Model: | C57BL/KsJ-db/db mice[2] |
| Dosage: | 2 mg/kg; 10 mg/kg |
| Administration: | Orally administration; 2-10 mg/kg; 4 weeks |
| Result: | Had antihyperglycemic potential and improved insulin resistance. |
IC 50
Plasmodium
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanoneSupplier
Huzhou ZhanShu Biotechnology Co.,Ltd Gold
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Chengdu Herbpurify Co.Ltd.
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