XPhos Pd G1
XPhos Pd G1 Basic information
- Product Name:
- XPhos Pd G1
- Synonyms:
-
- XPhos Palladacycle
- XPhos precatalyst
- [2-(2-AMinoethyl)phenyl](chloro)palladiuM-dicyclohexyl(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1)
- Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II)
- XPhos Pd G1
- Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct
- XPhos Pd
- Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl] palladium(II) methyl-t-butylether adduct, min. 98% [XPhos Palladacycle Gen. 1]
- CAS:
- 1028206-56-5
- MF:
- C41H59ClNPPd
- MW:
- 738.77
- EINECS:
- 633-034-5
- Product Categories:
-
- Buchwald Ligands&Precatalysts
- Buchwald Precatalysts Series
- Pd
- Mol File:
- 1028206-56-5.mol
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XPhos Pd G1 Chemical Properties
- Melting point:
- 205-210°C
- form
- Powder
- color
- white
- CAS DataBase Reference
- 1028206-56-5
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-52/53
- Safety Statements
- 26-61
- WGK Germany
- 3
- HS Code
- 2843909000
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XPhos Pd G1 Usage And Synthesis
Reaction
- Catalyst for cross-coupling reactions of electron-deficient anilines with aryl chlorides.
- Catalyst for rapid C-N bond-forming process at low catalyst loading.
- Catalyst for C-N cross-coupling reactions, at or below room temperature.
- Catalyst for the synthesis of tetracyclic indoles via intermolecular α-arylation of ketones.
- Catalyst for the cross-coupling of benzyl chlorides with cyclopropanol-derived ketone homoenolates
Uses
XPhos Pd G1 is used as androgen receptor modulator for treatment of disorders including prostate cancer.
Uses
Application Guide for Palladium Catalyzed Cross-Coupling Reactions
Catalyst used for:
- Amination / cyclization reactions
- C-N bond-forming reactions via packed-bed microreactors
- Boration of aryl chlorides
- Arylation of oxazole
- Cross-coupling reactions
Preparation
XPhos Pd G1 is an insoluble solid that can be prepared by cross-coupling reactions of imidazole derivatives with dioxane.
General Description
Material may contain up to 5% pentane
Physiological effects
XPhos Pd G1 has been shown to have anti-infectious properties against bacteria and viruses including influenza A, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and hepatitis B. It also has metabolic effects on the body by reducing levels of pyridine compounds and increasing pyrazolyl concentrations in the blood stream.
XPhos Pd G1Supplier
Shanghai Incat Chemtech Co.,Ltd. Gold
- Tel
- 021-57603038 13601791340
- 307593986@qq.com
Wu Han Lbpchem Chemical Co., Ltd. Gold
- Tel
- 02763499399 13797220777
- lpbchem@163.com
Wuhan phosphine biologic Pharmaceutical Co., LTD Gold
- Tel
- 15102702255 15102702255
- 35729423@qq.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
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XPhos Pd G1(1028206-56-5)Related Product Information
- Chloro(2-dicyclohexylphosphino-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98% [BrettPhos Palladacycle]
- XPhos Pd G3
- SPhos Palladacycle Gen. 4
- XPhos Pd G4
- Xantphos Pd G3
- BrettPhos Pd G3
- XPhos Pd G2
- RuPhos Pd G1 Methyl t--Butyl Ether Adduct
- SPhos Pd G2
- BrettPhosPalladacycle
- Palladacycle Gen. 3
- t-BuXphos Palladacycle Gen. 4
- RuPhos Palladacycle Gen. 4
- t-BuBrettPhos Palladacycle Gen. 3
- SPhos Pd G3
- SPhos Pd G1, Methyl t-Butyl Ether Adduct
- RuPhos Pd G2
- tBuXPhos Pd G1